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Sprycel® Tablets for Chronic Myeloid Leukemia
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Price range: $840.99 through $1,848.99
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What Sprycel Is and How It Works
Dasatinib is a tyrosine kinase inhibitor used for chronic myeloid leukemia and some cases of Philadelphia chromosome–positive acute lymphoblastic leukemia. It targets BCR-ABL and other kinases to help slow or stop the growth of abnormal white blood cells. YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing. With US shipping from Canada, you can streamline refills while keeping records in one place. Many people review Dasatinib cost without insurance to plan their therapy budgets. Sprycel® is the original brand; generic options may support affordability. Treatment decisions should follow your prescriber’s guidance and the official label.
This medicine works inside cancer cells by blocking signals that drive uncontrolled division. It can reduce disease activity when taken as directed. Results and tolerability vary by individual, disease phase, and prior therapies. Always follow your oncology team’s instructions for lab monitoring and follow-up.
Learn more about the condition in our guide to Leukemia Symptoms and explore the condition overview for Chronic Myeloid Leukemia.
Who It’s For
This treatment is indicated for adults and some children with chronic, accelerated, or blast phase CML that is Philadelphia chromosome positive. It is also used in Ph+ ALL for certain patients under specialist care. People with significant heart rhythm problems, uncontrolled low potassium or magnesium, or active bleeding disorders may need a different approach. Those on strong CYP3A4 inhibitors or inducers require careful review for safety. If you are pregnant, planning pregnancy, or breastfeeding, your prescriber will discuss risks and alternatives.
For additional background on related therapies, you can read our article on Nilotinib Guide.
Dosage and Usage
Tablets are taken by mouth, once daily, as directed. The label allows use with or without food. Swallow tablets whole with water. Do not crush, chew, or split. Your prescriber chooses a starting dose based on the condition and phase, then may adjust by response and tolerability. Take doses at the same time each day to support steady exposure. If stomach upset occurs, ask whether taking it with a light meal is appropriate.
Avoid grapefruit or grapefruit juice because it can raise medicine levels. Provide your clinician a full list of medicines, vitamins, and herbal supplements. Lab monitoring often includes blood counts, liver function tests, and ECG when indicated. If you experience severe side effects, contact your care team for advice. Do not change your dose unless your prescriber tells you to.
For an overview of mechanism and clinical use, see our explainer Dasatinib Guide.
Strengths and Forms
Film-coated tablets are available in several strengths commonly used in practice, including 50 mg and 100 mg options. Not all strengths are stocked at all times. Tablet colors and imprint codes differ by strength to help identification. Your exact dose, quantity, and refill interval depend on your prescription and treatment plan.
Missed Dose and Timing
If you miss a dose and it is close to the time for your next one, skip the missed dose and resume your regular schedule. Do not double up to make up for a missed tablet. If you vomit after taking a dose, do not take an extra tablet. Keep a simple reminder system, such as a phone alarm or calendar, to help maintain consistency.
Storage and Travel Basics
Store tablets at room temperature in the original bottle, tightly closed. Keep away from moisture and direct light. Do not store in a bathroom. Always keep out of reach of children and pets. When traveling, carry your medication in hand luggage along with a copy of your prescription. Use a travel pill case only if it preserves labeling and safety information. If you cross time zones, take the next dose according to your home schedule until your clinician advises otherwise. A brief travel letter from your prescriber may help during security checks.
Maintain a clean, dry area for storage at home. Discard tablets that are damaged, discolored, or past the labeled beyond-use date. Ask your pharmacist about local take-back programs for any unused medicine.
Benefits
This therapy offers targeted inhibition of BCR-ABL, which may help control disease activity with once-daily oral dosing. Many patients value the convenience of tablets compared with clinic-based infusions. Discuss any expected Sprycel cost per month with your care team when planning your treatment and monitoring schedule. The treatment can be adjusted by your prescriber if labs or tolerance require changes. Ongoing follow-up helps track response and manage side effects.
Side Effects and Safety
- Common effects: headache, nausea, diarrhea, fatigue, skin rash
- Fluid-related changes: swelling, pleural effusion, shortness of breath
- Blood count changes: low platelets, low neutrophils, anemia
- GI symptoms: abdominal discomfort, decreased appetite
- Musculoskeletal: muscle or joint pain
Serious but less common risks can include severe fluid accumulation, pulmonary arterial hypertension, bleeding events, infections, and heart rhythm changes such as QT prolongation. Seek urgent care for chest pain, fainting, trouble breathing, signs of severe infection, or unusual bleeding. Your clinician will monitor labs and may order imaging or ECG if indicated. Report all medicines you use, including over-the-counter products and supplements.
Drug Interactions and Cautions
Strong CYP3A4 inhibitors like certain azole antifungals and macrolide antibiotics may increase levels of this medicine. Strong CYP3A4 inducers such as rifampin or certain anticonvulsants may reduce effectiveness. Acid-reducing agents can affect absorption; follow label guidance for antacids and H2 blockers. Avoid St. John’s wort. People with heart rhythm issues, liver impairment, or a history of significant fluid retention need careful monitoring. Alcohol may worsen dizziness or stomach upset; ask your prescriber about safe use.
For background on another TKI, see our overview Bosulif Role.
What to Expect Over Time
Response to therapy is assessed with scheduled bloodwork and, when needed, bone marrow or molecular tests. Your clinician may discuss milestones and what they mean for your plan. Some side effects tend to appear early and improve with supportive measures. Others may require dose adjustments or a change in therapy. Staying consistent with daily dosing and appointments supports the best chance of disease control. If you face adherence challenges, talk with your team about practical supports.
Compare With Alternatives
Other approved TKIs for CML include Tasigna and Bosulif. Selection depends on phase of disease, prior therapy, comorbidities, and tolerability. Your oncology team will consider interactions, side effect profiles, and monitoring needs when recommending an option.
Pricing and Access
We provide transparent options so you can review Dasatinib price alongside brand alternatives. Our pharmacists can clarify prescription requirements and available pack sizes. You can also discuss savings before checkout and compare choices by refill interval. We continue to support access that Ships from Canada to US for eligible prescriptions under our cross-border model. While considering options, some patients ask about Sprycel Canadian pricing to understand differences from local quotes. Final charges depend on strength, quantity, and your prescriber’s directions.
For broader oncology choices, visit our category for Cancer. If your care plan involves switching therapies, review Gleevec or newer options like Scemblix and discuss clinical fit with your prescriber.
Availability and Substitutions
Supply can vary by strength and manufacturer. If a particular strength is out of stock, your prescriber may recommend an alternative strength or a different TKI. We cannot guarantee restock dates. Patients sometimes search for Dasatinib buy online when comparing availability between pharmacies. Your order will be filled according to your valid prescription and local regulations.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults diagnosed with Ph+ CML or specific cases of Ph+ ALL who can adhere to daily oral dosing and monitoring. It may not suit those with uncontrolled heart rhythm issues, severe liver disease, or high bleeding risk. Ask your clinician about supportive measures for side effects and how to coordinate lab schedules.
- Multi-month fills: reduce trips and help maintain continuity
- Refill reminders: set calendar alerts before you run low
- Budget planning: consider Dasatinib cost per pill vs pack sizes
- Interaction review: share full medication and supplement lists
- Documentation: keep copies of labs, ECGs, and clinic notes
Some patients prefer generic options for affordability while keeping follow-up unchanged. If your plan requires brand, your prescriber will note it on the prescription. We support encrypted checkout for order security.
Questions to Ask Your Clinician
- Is this the right TKI for my disease phase and history?
- Which lab tests do I need and how often?
- What are the most important side effects to watch for?
- How should I handle interactions with antacids or antibiotics?
- If I need to switch, what alternatives fit my situation?
Authoritative Sources
Manufacturer Prescribing Information
Health Canada Drug Product Database
Storage and Travel Basics
Before you place an order, review condition resources for Ph+ ALL and compare therapy guides such as Scemblix Uses. This helps align questions for your next appointment.
Ready when your prescription is? US delivery from Canada is available with prompt, express shipping with temperature-controlled handling when required. Disclaimer: Content is educational and not a substitute for professional medical advice. Your clinician’s instructions and the official label should guide your care.
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How is dasatinib different from imatinib or nilotinib?
These medicines are all tyrosine kinase inhibitors but differ in selectivity, dosing, and side effect profiles. Dasatinib inhibits BCR-ABL and additional kinases, which can influence tolerability and fluid-related effects. Imatinib is often used earlier in therapy, while nilotinib has specific fasting requirements and QT considerations. Your oncology team chooses based on disease phase, prior response, comorbidities, and interaction risks. Never switch without consulting your prescriber.
Can I take antacids or acid reducers with this medicine?
Acid-reducing agents can affect how dasatinib is absorbed. The label provides timing guidance for antacids and cautions with H2 blockers and proton pump inhibitors. Do not change or add acid reducers without asking your clinician. If you need heartburn relief, your prescriber may recommend a specific product and timing plan that fits your regimen.
What monitoring will I need while on treatment?
Monitoring often includes complete blood counts, liver enzymes, and assessments for fluid retention. Your clinician may request ECGs to watch for QT changes if you have risk factors or are on interacting medicines. Visit schedules vary by disease phase and response. Report new symptoms promptly. Keep copies of test results for your records and share them at each appointment.
Should I avoid any foods or drinks?
Avoid grapefruit and grapefruit juice because they can increase dasatinib levels and the risk of side effects. Alcohol can worsen dizziness or stomach irritation, so discuss safe intake with your prescriber. Maintain a balanced diet and adequate hydration unless your care team advises otherwise.
What if I become pregnant while taking dasatinib?
Tell your clinician right away. This medicine may cause fetal harm. Your prescriber will discuss stopping therapy and alternative options. Effective contraception is recommended during treatment and for a period after the last dose as advised by the label. Do not breastfeed while on therapy and for the timeframe in the official guidance.
Can I split or crush the tablets?
No. Tablets should be swallowed whole with water. Do not split, crush, or chew them. Altering tablet integrity can change exposure and increase the risk of side effects. If you have trouble swallowing tablets, speak with your clinician about options and supports.
How quickly will I know if it’s working?
Your care team will review lab results over time to assess response. Some changes are checked within weeks to months, such as blood counts and molecular markers, but timing varies by individual and disease phase. Keep all appointments and take your dose consistently. Your prescriber will explain what each result means for your plan.
