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Delstrigo® Tablets for HIV-1
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Delstrigo is a once-daily prescription tablet used to treat HIV-1 in adults and certain adolescents. You can arrange US shipping from Canada and follow your prescriber’s guidance. If you pay without insurance, this page explains strengths, safety, and access clearly.
What Delstrigo Is and How It Works
Buy Delstrigo tablets after your clinician prescribes this complete HIV-1 regimen. Delstrigo® combines three medicines: doravirine (an NNRTI), lamivudine (an NRTI), and tenofovir disoproxil fumarate, another NRTI. Together, they help lower the amount of virus in the blood when taken exactly as directed. This medicine is designed to be a full regimen, so additional antiretrovirals are usually not added.
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing. Learn more about HIV care in our condition hub Hiv and see our focused article Delstrigo Medication For Hiv for a concise overview.
Who It’s For
This treatment is indicated for adults and adolescents who meet label criteria, often those weighing at least 35 kg. It may be started in people new to therapy, or used to replace a stable regimen when certain resistance and tolerance conditions are met. People with significant kidney disease or underlying bone issues may need a different option. Those with hepatitis B require careful evaluation because stopping therapy can lead to serious HBV flares.
Dosage and Usage
Take one tablet by mouth once daily, with or without food. Swallow whole with water. Try to take it at the same time each day. Do not combine it with other complete regimens or products containing lamivudine, tenofovir, or other doravirine-class agents. Your prescriber may order baseline labs, including kidney function and hepatitis B testing, before you begin.
General administration tips:
- Daily routine: choose a consistent time that fits your schedule.
- Food: may be taken with meals or on an empty stomach.
- Do not split or crush: keep the tablet intact unless your prescriber says otherwise.
- Alcohol and substances: discuss use that may affect adherence or organ health.
When uncertain, follow the official label and your prescriber’s instructions. For broader context on therapy classes, see our category Antivirals.
Strengths and Forms
Delstrigo 100/300/300 mg tablets are film-coated oral tablets. Bottles commonly contain a 30-day supply. Availability can vary by market. Your prescribed bottle may include a desiccant; keep tablets dry and in the original container.
Missed Dose and Timing
If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular schedule. Do not double up. If vomiting occurs shortly after a dose, consult the official label or your prescriber for guidance on whether to take another tablet.
Storage and Travel Basics
Store at room temperature in a dry place, away from excess heat and moisture. Keep in the original bottle with the lid tightly closed and out of reach of children and pets. When you travel, carry your medication in your hand luggage with a copy of your prescription. Use a daily reminder or travel checklist to keep your routine steady across time zones. If you need help with packing or timing, your pharmacist can support you.
Pen Handling and Sharps Disposal
This product is an oral tablet, so no pen or sharps handling is required.
Benefits
This complete regimen simplifies therapy to one tablet once daily. It can be taken with or without food, which helps fit many schedules. The combination targets viral replication with two nucleoside analogs and an NNRTI, offering a balanced approach for eligible patients. Many people appreciate the single-bottle convenience and straightforward daily timing that can support adherence.
Side Effects and Safety
Common effects can include:
- Nausea or stomach discomfort
- Headache or tiredness
- Diarrhea
- Trouble sleeping or abnormal dreams
Serious or rare risks may include kidney problems or reduced bone mineral density, especially due to the tenofovir component. Lactic acidosis and severe liver problems, including hepatomegaly with steatosis, can occur with NRTIs. Stopping therapy in people with chronic hepatitis B may cause serious HBV flares. Allergic reactions, mood changes, or immune reconstitution syndrome can also occur. Seek urgent care for severe symptoms such as trouble breathing, swelling, chest pain, or persistent vomiting.
Drug Interactions and Cautions
Strong CYP3A inducers can lower doravirine levels and may reduce effectiveness. Examples include rifampin, carbamazepine, oxcarbazepine, phenobarbital, phenytoin, and St. John’s wort. Avoid combining with other complete HIV regimens or products that duplicate lamivudine or tenofovir. Use caution with medicines that affect kidneys or bone health. Always tell your clinician and pharmacist about all prescription drugs, OTC products, and herbal supplements you use. For a helpful refresher, visit our guide Drug Interactions.
What to Expect Over Time
With steady daily use, your prescriber will monitor viral load, CD4 count, kidney function, and overall tolerance at regular visits. Some side effects may appear early and improve with time. Keep a simple log if you notice new symptoms. Continue safer-sex practices and follow public health guidance for partners. If you ever plan to stop or switch therapy, do so only under clinical supervision to reduce the risk of viral rebound or HBV flares.
Compare With Alternatives
Several complete regimens may be considered depending on your history. Two options include Dovato, a two-drug regimen for selected adults, and Odefsey, a once-daily combination that contains tenofovir alafenamide instead of TDF. Other choices, such as multi-tablet combinations, may be recommended in special situations. Your prescriber will match therapy to your resistance profile, organ health, and treatment goals.
Pricing and Access
We support transparent access with clear listings and a simple checkout. The Delstrigo cash price can reflect Canadian marketplace dynamics. Many patients compare options by reviewing pack size and refill timing rather than focusing only on a single line item. You can view Canadian pricing details with US delivery from Canada and decide when to place your order.
If you are looking for coupons, see current offers on our Promotions page. For background on HIV treatment choices, our article National Hiv Testing Day covers useful prevention and screening reminders. Our checkout is encrypted to help protect your information.
Two quick actions:
- Savings review: compare Canadian pricing with your current pharmacy.
- Pricing check: confirm your bottle size and refill plan online.
Availability and Substitutions
Supply can change over time. If Generic Delstrigo equivalent options become available in your region, your prescriber can advise whether substitution is appropriate. If this item is temporarily unavailable, your prescriber may recommend an alternative complete regimen that fits your medical history. We keep listings updated, but availability can vary by jurisdiction and manufacturer production.
Patient Suitability and Cost-Saving Tips
Good candidates are those who meet label criteria, can follow a once-daily routine, and have kidney and bone status compatible with tenofovir DF. People with advanced kidney disease, certain drug interactions, or known resistance patterns may need a different regimen.
Ways to manage costs and support adherence:
- Buy doravirine/lamivudine/tenofovir disoproxil fumarate tablets: confirm it is the exact item on your prescription.
- Multi-month fills: fewer refills can reduce overall time and effort.
- Refill reminders: set calendar alerts so you do not run out.
- Medication list: bring it to visits to check for interactions.
- Lab coordination: align refill timing with routine bloodwork when possible.
Questions to Ask Your Clinician
- Is this regimen appropriate for my resistance profile and organ health?
- What baseline labs will you monitor, and how often should I follow up?
- Could any of my current medicines reduce this treatment’s effectiveness?
- What signs suggest I should call your office promptly?
- How would we plan a safe switch if my needs change later?
Authoritative Sources
| Source | Link |
|---|---|
| Manufacturer Product Page | Merck PI |
| FDA Prescribing Information | FDA DailyMed |
| Health Canada Database | DPD Listing |
Closing
You can place your order online and track progress easily. Ships from Canada to US with prompt, express shipping and temperature-controlled handling when required. This content is educational and does not replace your clinician’s advice or the official label.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
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Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
Can I take this tablet with food or on an empty stomach?
Yes. The combination can be taken with or without food. Try to take it at the same time every day to support consistent levels. If you have nausea, taking it with a light meal may help. Avoid missing doses and keep your routine steady during travel. Tell your healthcare professional about all other medicines, vitamins, and supplements you use to help avoid interactions.
What if I have hepatitis B as well as HIV-1?
Your prescriber will screen for hepatitis B before starting therapy. Stopping treatment can cause serious HBV flares, so do not discontinue on your own. If you have HBV, your clinician may plan additional monitoring and follow-up. Discuss vaccines, liver health, and any alcohol use. For cost questions about related components, search for doravirine lamivudine tenofovir disoproxil fumarate price to compare markets and programs.
Which medicines can reduce this regimen’s effectiveness?
Strong enzyme inducers can lower levels of one component. Examples include rifampin, carbamazepine, phenobarbital, phenytoin, oxcarbazepine, and St. John’s wort. Always share your full medication list with your prescriber and pharmacist. Some kidney- or bone-affecting drugs may also require caution. If you need a new prescription, remind your clinician about your HIV therapy during every visit.
How do I store it at home and while traveling?
Keep tablets in the original bottle at room temperature and away from moisture. Close the cap tightly and store out of reach of children and pets. When you travel, keep medication in your carry-on with a copy of your prescription. Use a reminder app or calendar alert to maintain your dosing schedule across time zones and minimize missed doses.
What happens if I miss a dose?
If you forget a dose, take it when you remember. If it’s close to the time for your next dose, skip the missed dose and resume your normal schedule. Do not take two doses at once. If vomiting occurs soon after taking a tablet, ask your prescriber whether to take another dose. Keep consistent daily timing to support effectiveness and ongoing viral suppression.
Can I switch from my current HIV regimen to this one?
Some people may switch if they are already virologically suppressed and meet criteria in the official label, including no history of treatment failure or known resistance to any component. Your clinician will review your labs, prior therapies, and potential interactions before making a decision. Never change or stop antiretroviral therapy without professional guidance.
Are there cost-saving tips if I’m paying out of pocket?
Consider multi-month fills when appropriate, and set refill reminders so you don’t run out. Compare Canadian pricing with local options, and review any promotions from the pharmacy. Pack size and refill cadence often influence overall costs more than a single line item. Ask your prescriber for documentation that helps with reimbursement if you later submit claims.
