Dificid® (fidaxomicin) 200 mg Tablets for C. difficile Infection

What Dificid® Is and How It Works

Dificid® (fidaxomicin) is an oral antibiotic for treating Clostridioides difficile infection (CDI), also called C. difficile-associated diarrhea. The usual strength is 200 mg tablets taken twice daily for 10 days. Many patients compare Dificid® options by searching for Dificid price and ways to buy Dificid online. If cost is a concern, some patients also look for Dificid without insurance to understand out-of-pocket options.

Fidaxomicin belongs to a macrolide-like antibacterial class. It targets C. difficile in the gut and has minimal systemic absorption. It works by inhibiting bacterial RNA polymerase, which limits C. difficile growth while sparing many normal gut bacteria. Lower disruption of gut flora may help reduce recurrence compared with some alternatives.

YouDrugstore is a licensed Canadian pharmacy based in Manitoba and meeting Canadian pharmacy standards. Licensed pharmacists review prescriptions before dispensing. We offer brand and generic medicines at Canadian prices and also carry OTC health products, with online ordering and friendly customer-service chat during posted office hours. When we source products, we work with licensed, vetted international partner pharmacies to supply authentic brands across a broad selection at affordable prices.

Dosage and Usage

Dosing for adults is usually 200 mg by mouth twice daily for 10 days. Pediatric dosing differs and follows a prescriber’s direction. Take with or without food. Swallow tablets whole with water.

• Start: Use Dificid® exactly as prescribed for the full course.
• Usual adult dose: 200 mg twice daily for 10 days.
• If you miss a dose: Take it when remembered unless it is almost time for the next dose. Do not double doses.
• Do not use for infections outside the gut. It is not effective for systemic infections.
• If symptoms worsen or severe dehydration occurs, contact your prescriber.

Storage and travel tips:

• Store at 20–25°C (68–77°F). Short excursions 15–30°C are acceptable.
• Keep tablets in the original bottle with the cap tightly closed.
• Protect from moisture and excess heat. Do not freeze.
• When you travel, pack enough tablets for the full 10-day course in your carry-on.
• Keep out of reach of children and pets.

If you have questions about how to use Dificid®, a pharmacist can help. Our team can also guide you on how to upload a prescription and place an order. You can review pack options any time on the Dificid® product page.

Benefits and Savings

Dificid® treats CDI with targeted activity in the intestines. Clinical studies show similar cure rates to oral vancomycin, with lower recurrence in many patient groups. Less disruption of normal gut flora may support recovery. The 10-day course and oral tablets keep treatment simple.

Ordering through YouDrugstore offers access to Canadian pricing. Many customers report 60–80% savings versus typical U.S. pharmacy prices. This can help if you are managing Dificid cost or comparing the Dificid 200 mg price. We also support patients paying without insurance to understand options and reduce out-of-pocket costs.

Our customer-service chat is available during posted office hours to help with ordering steps and shipment questions. Pharmacists can address medication questions before your order ships.

Side Effects and Safety

Most people tolerate Dificid® well due to low systemic absorption. Common effects are usually mild and related to the gut.

• Common: nausea, vomiting, abdominal pain, constipation, flatulence.
• Less common: anemia, neutropenia, headache.
• Serious: hypersensitivity reactions including rash, angioedema, or dyspnea. Seek emergency care if signs of severe allergy occur.
• CDI complications: severe diarrhea, dehydration, blood in stool, or abdominal swelling need medical attention.

Drug interactions are uncommon, but fidaxomicin is a P-glycoprotein (P-gp) substrate. Strong P-gp inhibitors (for example, cyclosporine) can increase exposure. Prescribers may use caution in such cases. Tell your prescriber about all medicines and supplements.

Use during pregnancy or breastfeeding only if the potential benefit justifies potential risk. Systemic exposure is low, but data are limited. Dificid® is approved for adults and for pediatric patients 6 months and older. Pediatric dosing and formulations may differ.

Onset Time

Many patients see symptom improvement within 2–3 days. Hydration and supportive care remain important. Complete the 10-day course even if symptoms improve earlier. Finishing the full course helps reduce the risk of recurrence.

Compare With Alternatives

Oral vancomycin is a standard alternative for CDI. Cure rates are comparable in many studies, but Dificid® often shows lower recurrence in subgroups such as older adults or those with prior episodes. Vancomycin is widely used and may be less expensive, depending on local pricing and coverage.

Metronidazole was used in the past for mild CDI but is no longer preferred for initial therapy in most guidelines due to lower efficacy. It may be considered when other options are unavailable and under prescriber guidance.

Bezlotoxumab is not an antibiotic. It is a monoclonal antibody given once by infusion alongside standard antibiotics to reduce the risk of recurrence in high-risk patients. It is considered for those with prior recurrences or other risk factors.

Choice of therapy depends on severity, prior episodes, comorbidities, and access. Prescribers may weigh recurrence risk, cost, and local availability when selecting treatment.

Combination Therapy

Dificid® is usually used alone to treat CDI. In patients with high recurrence risk, clinicians may add bezlotoxumab during the antibiotic course to lower recurrence. Probiotics are sometimes considered, but evidence is mixed, and some patients may be at risk, especially if immunocompromised. Do not start other antibiotics unless a prescriber advises they are necessary for another condition.

Patient Suitability and Cost-Saving Tips

Dificid® can be considered for adults and children 6 months and older with CDI. It is not used for non-C. difficile diarrhea or infections outside the intestines. It should not be used in patients with known hypersensitivity to fidaxomicin or any ingredient in the formulation. Discuss recent antibiotic exposure, inflammatory bowel disease, and recurrence history with your prescriber.

You can manage costs by comparing the Dificid 200 mg price across pack sizes and pharmacies. Ordering a complete course at once helps avoid interruptions. Ask customer service about current Dificid discount opportunities. We offer reorder reminders on request, which can help you prepare if your prescriber plans a future course. Multi-pack or bulk promotions may be available when appropriate and prescribed.

For current promotions, see our Dificid coupon page for offers and bulk options. This can help lower the Dificid cash price while keeping access to the original brand.

If you pay out of pocket, our team can outline ways to reduce the Dificid no insurance price without compromising quality. We aim to make Dificid® for sale at fair Canadian pricing with clear checkout and helpful support.

Authoritative Sources

For detailed prescribing information, see the official Dificid patient website. U.S. label materials are available on the FDA Drugs@FDA Dificid page. Canadian drug listings can be found via the Health Canada Drug Product Database.

We are ready to help you order Dificid® online at Canadian prices. Our licensed pharmacists review each prescription, and our team supports you from checkout to delivery. We offer prompt, express, cold-chain shipping and careful packaging to protect your order in transit.

Content on this page is for general information and does not replace advice from your prescriber. Always follow your prescriber’s directions and the patient information provided with your medicine. Seek medical help right away for severe or worsening symptoms.