Cosopt® Ophthalmic Solution for Open-Angle Glaucoma

What Cosopt Is and How It Works

This prescription eye drop reduces elevated eye pressure in glaucoma and ocular hypertension. It combines a carbonic anhydrase inhibitor with a beta blocker to lower intraocular pressure. You can order with US delivery from Canada, and we explain options to save without insurance.

YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

Cosopt® contains dorzolamide and timolol. Dorzolamide decreases aqueous humor production by inhibiting carbonic anhydrase in the ciliary body. Timolol is a nonselective beta blocker that also reduces aqueous humor formation. Together, they may lower eye pressure more than either agent alone. Many people use this combination when single-agent therapy is insufficient or not well-tolerated.

If your prescriber has directed a fixed-combination drop, Dorzolamide 2% / Timolol 0.5% Ophthalmic Solution is a commonly used option. Use as prescribed and attend follow-up eye pressure checks. Do not change or stop therapy without guidance from your eye care professional.

Who It’s For

This medicine is prescribed to reduce intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It may be selected when pressure is not controlled on a single agent, or when simplifying to a single bottle is preferred.

Avoid use if you have a known hypersensitivity to dorzolamide, timolol, sulfonamides, or any component. Because the beta blocker is systemically absorbed, patients with asthma, severe chronic obstructive pulmonary disease, bradycardia, second or third-degree heart block, overt cardiac failure, or cardiogenic shock should not use it unless their prescriber determines benefit outweighs risk. Tell your clinician if you have kidney or liver problems, corneal disease, or are pregnant or breastfeeding.

Contact lens wearers should discuss preservative exposure and proper lens handling with a clinician. Some bottles contain benzalkonium chloride, which can interact with soft lenses.

Dosage and Usage

The usual schedule is one drop in the affected eye or eyes twice daily, morning and evening. Follow the exact directions on your prescription label.

How to apply:

• Hand hygiene first: wash and dry your hands.
• Prepare the bottle: avoid touching the dropper tip.
• Instill the drop: tilt your head back, pull down the lower eyelid, and place one drop in the pocket.
• Reduce drainage: gently press the inner corner of your eye for 1–2 minutes.
• Wait between products: separate other eye drops by at least 5–10 minutes.
• Ointments last: apply any eye ointment after drops.

Contact lens steps: remove soft lenses before instillation and wait at least 15 minutes before reinserting unless your prescriber advises otherwise.

If you experience irritation or vision changes after dosing, avoid driving until your sight clears.

Strengths and Forms

Common presentations include multi-dose bottles with preservative and single-use units that are preservative-free. Availability may vary by country and manufacturer.

• Fixed-combination solution: dorzolamide 2% with timolol 0.5%.
• Multi-dose bottle: typically contains benzalkonium chloride.
• Preservative-free unit doses: single-use containers; discard after one use.

People sensitive to preservatives may prefer single-use presentations. Ask your prescriber which format fits your eyes and dosing schedule. Some patients inquire about Cosopt PF price; preservative-free options can differ in cost and pack size compared with bottles.

Missed Dose and Timing

If you miss a dose, use it when you remember. If it is close to the next time, skip the missed dose and resume the regular schedule. Do not instill extra drops to make up for a missed dose. Consistent timing helps maintain steady pressure control.

Storage and Travel Basics

Store at room temperature as directed on the label, and keep the bottle tightly closed. Protect from contamination by not touching the tip to your eye, fingers, or any surface. Do not freeze and avoid excessive heat. Discard the bottle or unit doses by the labeled discard date or the period after opening shown on the package.

For travel, keep the bottle in a clean case within your hand luggage. Carry your prescription, especially when flying. If you use single-use containers, bring a few extra in case of delays. Keep all eye medicines away from children and pets. For preservatives and packaging, follow specific manufacturer instructions. When uncertain, refer to the official label.

Benefits

This combination therapy can help reduce intraocular pressure through two mechanisms at once. Using one bottle instead of two may simplify routines and reduce preservative exposure compared with separate agents. Many patients appreciate the twice-daily schedule when a prostaglandin alone is not enough.

Side Effects and Safety

Common effects may include burning or stinging on instillation, blurred vision, dry eye, tearing, foreign body sensation, eye redness, bitter or unusual taste, and mild eyelid irritation. These are usually transient.

Serious or rare risks can include allergic reactions, corneal changes, severe eye irritation, shortness of breath or wheezing, slow heart rate, low blood pressure, fatigue, depression, or masking signs of low blood sugar in diabetics. Stop the drops and seek medical help right away if you notice symptoms of a serious reaction such as breathing difficulty, swelling, rash, or chest pain.

Beta blockers can interact with existing heart or lung conditions. Discuss your full medical history and all medicines with your prescriber.

Drug Interactions and Cautions

Tell your clinician about all medicines and supplements. Interactions may occur with oral beta blockers, calcium channel blockers, digoxin, clonidine, antiarrhythmics, and other eye drops containing beta blockers. Combining with oral carbonic anhydrase inhibitors may raise the risk of systemic effects. Using other sulfonamide-containing drugs requires caution if you have a history of sulfonamide reactions.

Remove soft contact lenses before dosing when using a benzalkonium chloride–preserved bottle. Wait at least 15 minutes before reinsertion.

What to Expect Over Time

With regular use, eye pressure may decrease as directed therapy continues. Your clinician will assess pressure, optic nerve health, and visual fields over time. Some people need adjustments to their regimen or additional agents.

To support consistent use: pair doses with daily routines, set reminders, and bring your drops to appointments. Report new symptoms promptly to your eye care professional.

Compare With Alternatives

Other options include a prostaglandin analog or a different fixed combination. For a beta blocker plus alpha agonist alternative, see Combigan. If your prescriber suggests a prostaglandin, review Latanoprost Ophthalmic Solution. Choice depends on your eye pressure targets, tolerability, and medical history.

Pricing and Access

We display transparent options with Canadian pricing to help you compare formats and pack sizes. You may also review Dorzolamide Timolol cash price details on each product page. Savings vary by manufacturer and quantity.

For occasional offers, see our Promotions. If you are looking for a Dorzolamide Timolol ophthalmic solution coupon, check that page for current terms. We provide Ships from Canada to US, and our encrypted checkout helps protect your details.

Availability and Substitutions

Supply can vary by format and manufacturer. If a specific presentation is unavailable, your prescriber may recommend separate agents or a preservative-free alternative. Stock status on our site reflects current inventory and may change. Ask your clinician before substituting any eye medicine.

Patient Suitability and Cost-Saving Tips

This treatment may be considered for adults with open-angle glaucoma or ocular hypertension who require more than one mechanism to reach target pressure. It may not be suitable if you have reactive airway disease, certain heart rhythm issues, severe heart failure, or sulfonamide sensitivity. Share your full history so your prescriber can decide safely.

Ways to manage costs and convenience:

• Multi-month fills: fewer refills and potential per-unit savings.
• Refill reminders: set calendar alerts for timely reorders.
• Right size: choose unit-dose or multi-dose based on daily use.
• Lens planning: coordinate lens-free windows around dosing.
• Follow-up: bring your drop to visits for technique checks.

If you prefer to pay directly, some customers review Dorzolamide Timolol pay cash options during checkout. Your clinician can also discuss whether a different class could meet your goals with fewer drops.

Questions to Ask Your Clinician

• Is this combination appropriate for my type of glaucoma?
• How should I space this with other eye medicines?
• Would a preservative-free unit-dose be better for my eyes?
• Should I avoid it due to asthma, COPD, or heart conditions?
• What signs mean I should contact the clinic right away?
• How long after starting should I return for pressure checks?
• Could separate components offer similar control for me?

Authoritative Sources

Health Canada Product Monograph

DailyMed: COSOPT (dorzolamide hydrochloride and timolol maleate)

DailyMed: dorzolamide and timolol ophthalmic solution (generic)

Storage and Travel Basics

Key reminders: keep out of reach of children, protect the dropper tip, and discard according to the labeled period after opening. For longer trips, pack extra supply and a copy of your prescription. Use a protective case to prevent leaks or damage in transit.

Explore related items and conditions on our site: learn more about Open Angle Glaucoma, find therapies for Ocular Hypertension, browse Ophthalmology, and review related products such as Timolol, Timolol Maleate, and Azopt. For general allergy education, see Claritin Allergy Medicine.

Ready to proceed? Add to cart and check out for prompt, express shipping with US shipping from Canada. Always follow your prescription. This information is not a substitute for professional medical advice.