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Dovato® (dolutegravir/lamivudine) Tablets for HIV-1 Treatment
$1,606.99
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What Dovato Is and How It Works
Dovato® combines dolutegravir 50 mg and lamivudine 300 mg in one tablet. It is a complete regimen for many adults with HIV‑1. You take one tablet once daily, with or without food. This page helps you review Dovato price and practical details. Many people also ask about Dovato cost without insurance when planning long‑term therapy.
YouDrugstore is a licensed Canadian pharmacy in Manitoba that follows Canadian pharmacy standards. A licensed pharmacist reviews each prescription before dispensing. You can order online, and our customer-service chat is available during posted hours for support. We offer brand and generic medicines at Canadian prices and also stock OTC health products.
We source through licensed, vetted partner pharmacies internationally so you receive authentic brand medication, broad selection, and fair pricing. Dovato® is used for treatment‑naive adults with no known resistance to either component and no hepatitis B co‑infection. It is also used for eligible patients switching from a stable regimen who are virologically suppressed. The fixed strength is Dovato 50 300 mg (often noted as Dovato tab 50 300mg). If you need a Dovato rx, your prescriber will decide if it suits your situation.
Dolutegravir is an integrase inhibitor. It blocks the HIV integrase enzyme to stop viral DNA from entering host DNA. Lamivudine is a nucleoside reverse transcriptase inhibitor (NRTI). It blocks reverse transcriptase to reduce viral replication. The two drugs work together to lower viral load and raise CD4+ counts. This is what Dovato is used for in current care. You can read more under FDA resources if you search for Dovato FDA documents.
Dosage and Usage
The usual dose is one Dovato tablet once daily.
- Take with or without food, at the same time each day.
- If you miss a dose, take it when remembered. If your next dose is soon, skip the missed dose and resume your schedule. Do not double up.
- Avoid taking antacids or iron/calcium supplements at the same time. Take Dovato two hours before or six hours after these products. You may take them together with a meal if advised by your provider.
- Swallow the tablet whole. Do not split or crush unless a clinician tells you to do so.
- Tell your clinician about all medicines you take, including OTC and herbals.
Storage and travel tips:
- Store at 20–25°C (68–77°F); short excursions 15–30°C are allowed.
- Keep the bottle tightly closed. Do not remove the desiccant.
- Protect from moisture and heat. Keep out of reach of children.
- When you travel, keep tablets in your carry‑on in the original bottle.
- Carry a copy of your prescription and a current medication list.
Benefits and Savings
Dovato® offers once‑daily dosing in a single pill. It reduces daily pill burden while maintaining strong viral suppression in appropriate patients. Many people report good tolerability and stable lab results over time. Fewer antiretroviral components may simplify care and may reduce certain drug exposures compared with three‑drug regimens.
Buying from a Canadian pharmacy can lower your monthly spend. Typical savings vs US retail can be 60–80% depending on supply. If you compare price of Dovato against US pharmacy cash prices, the difference may be significant. This can help if you are paying without insurance or if you have a high deductible. You can ask us about multi‑month options to reduce your per‑month cost.
Side Effects and Safety
Common side effects are usually mild to moderate and often improve over time.
- Nausea, diarrhea, or stomach discomfort
- Headache
- Insomnia or vivid dreams
- Dizziness or fatigue
- Weight gain
Serious effects are less common but need urgent care.
- Allergic reaction (rash, fever, swelling, or breathing trouble)
- Liver problems (dark urine, yellowing of skin/eyes, right‑side pain)
- Lactic acidosis signs (deep or rapid breathing, weakness, stomach pain)
- Depression or mood changes
- Immune reconstitution reactions
Drug interactions can occur. Do not use with dofetilide. Rifampin, certain anticonvulsants, and St. John’s wort may lower dolutegravir levels. Metformin dose limits may apply. Mineral supplements and antacids reduce absorption, so separate timing as noted. People with hepatitis B should not rely on lamivudine alone; stopping lamivudine can worsen hepatitis B. Discuss pregnancy and breastfeeding plans with your clinician. Renal impairment may limit use because lamivudine needs dose adjustment. The fixed‑dose tablet does not allow that.
Onset Time
Viral load often falls within the first weeks. Many patients who start Dovato® reach suppression in 8–24 weeks, depending on baseline viral load and adherence. CD4+ counts may rise over months. Routine lab monitoring guides your care team on response and safety.
Compare With Alternatives
Many patients compare Dovato® with other integrase‑based regimens. Triple therapy options like bictegravir/tenofovir alafenamide/emtricitabine (Biktarvy) remain common. Another option is Triumeq®, which contains dolutegravir/abacavir/lamivudine. Triumeq requires HLA‑B*5701 testing and may not suit those with certain cardiac risks. Two‑tablet regimens built around raltegravir are also used; Isentress® must be taken with companion NRTIs.
Dovato® may not be right for people with hepatitis B co‑infection or baseline resistance to either component, or very high baseline viral load. In those cases, a three‑drug regimen may be preferred. Your clinician will match a regimen to your history, labs, and goals. Some patients also ask about long‑acting injectables. Those are different approaches and have distinct dosing schedules and clinic visit needs.
Combination Therapy
Dovato® is a complete regimen. Do not take it with other HIV medicines unless a clinician tells you to do so. If you have hepatitis B co‑infection, your clinician may recommend an HBV‑active backbone. In that case, Dovato® may not be appropriate. Always review any new medication or supplement for interactions before starting it.
Patient Suitability and Cost-Saving Tips
Dovato® can suit adults who are treatment‑naive without known resistance, HBV co‑infection, or severe renal impairment, and for eligible patients switching while suppressed. Adolescents who meet weight thresholds may also qualify. The exact choice depends on your medical history, co‑medications, and lab results.
To manage costs, ask about 90‑day supplies. Multi‑month fills can reduce your effective Dovato cost per month. We can send helpful reorder reminders before you run low. If you are comparing dovato cost with insurance and cash prices, we can provide current quotes for each available supply size.
For current offers and potential bulk options, see our promotions page for any dovato coupon opportunities. We also support education. You can read about HIV testing awareness in our article National Hiv Testing Day 2025 Get Tested Know Your Status. If you want more background on the condition, visit our condition pages for Hiv Infection and Hiv 1 Infection.
You may have seen a Dovato commercial or read patient stories. Real‑world experiences vary. Always base changes on guidance from your care team. If you prefer brand information, we can share details about the Dovato manufacturer and packaging. The Dovato company is ViiV Healthcare.
Authoritative Sources
For full prescribing information, see the FDA prescribing information for Dovato. The manufacturer provides resources at ViiV Healthcare’s Dovato page. European details are available in the EMA product assessment.
YouDrugstore makes it simple to order Dovato® from Canada. Our team supports you from checkout to delivery. We offer prompt, express, cold-chain shipping and careful packaging. Chat with us during posted hours if you have order or account questions. A pharmacist can address medication questions before dispensing.
Disclaimer: This information is not a substitute for professional medical advice, diagnosis, or treatment. Always ask your healthcare provider about your specific situation, dosing, and safety monitoring.
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How much does Dovato cost without insurance?
Pricing varies by supply size and market changes. Many customers see 60–80% savings compared with typical US cash prices. Ask us for a current quote and options for multi‑month fills to lower the Dovato cost per month. We can also explain any available promotions and bulk pricing.
What is included in each Dovato tablet?
Each Dovato tablet contains dolutegravir 50 mg and lamivudine 300 mg. This is often written as Dovato 50 300 mg. It is a complete regimen for many adults with HIV‑1 when criteria are met. Take one tablet daily, with or without food, unless your clinician advises otherwise.
How fast does Dovato work to lower viral load?
Viral load often declines within weeks, and many patients reach suppression by 8–24 weeks. Timing depends on baseline viral load, adherence, and other factors. Regular labs guide your care team and confirm progress. Report side effects promptly so your clinician can support adherence and safety.
Are there key interactions or medicines to avoid with Dovato?
Do not take Dovato with dofetilide. Separate antacids and iron or calcium supplements to avoid lowering absorption. Certain anticonvulsants, rifampin, and St. John’s wort can reduce dolutegravir levels. Metformin dosing may need review. Share all medicines and supplements with your clinician and pharmacist.
What are common side effects of Dovato?
Common effects include nausea, headache, diarrhea, insomnia, dizziness, and fatigue. Weight gain can occur. Serious reactions like severe rash, liver problems, or lactic acidosis are less common but need urgent care. Always contact your care team if you feel unwell or notice new or worsening symptoms.
Where can I see today’s Dovato price and savings?
Contact our team or start a checkout quote to see today’s Dovato price. We can review options for 30‑, 60‑, or 90‑day supplies and discuss how multi‑month fills may reduce the per‑month cost. We also share current promotions and answer ordering or shipping questions.