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Duloxetine

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Duloxetine is a medication that belongs to the class of drugs known as selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). It is primarily used to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), and neuropathic pain associated with diabetic peripheral neuropathy (DPN). Additionally, it may be prescribed for managing pain related to fibromyalgia, chronic low back pain, and osteoarthritis of the knee.

Benefits

Duloxetine works by blocking the reuptake of serotonin and norepinephrine in the brain, which helps alleviate symptoms of depression and anxiety. It also has an effect on the central nervous system that can help control pain.

How to Use

It is recommended to take Duloxetine with food to help prevent nausea. A lower starting dose may be prescribed to allow the body to adjust to the medication. The typical therapeutic dose is reached within one to two weeks, although some patients may notice improvements within the first week, while others may take up to four weeks to see results.

Possible Side Effects

  • Constipation
  • Diarrhea
  • Dizziness
  • Dry mouth
  • Headache
  • Decreased appetite
  • Sleepiness

These may not be all the side effects of Duloxetine.

Warnings and Precautions

Duloxetine is contraindicated for individuals with severe kidney disease, liver disease, or allergies to the medication. It should not be taken with MAOIs, fluvoxamine, or certain antibiotics. Consult your doctor if you have high blood pressure, eye issues, a bleeding disorder, low sodium levels, or difficulty urinating before taking this medication.

Storage

Store Duloxetine capsules in their original packaging at room temperature (15°C to 30°C or 59°F to 86°F), in a dry place away from direct sunlight. Do not use the medication after the expiry date on the box.

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