Exemestane (Aromasin®) 25 mg Tablets for Hormone-Positive Breast Cancer

What Exemestane Is and How It Works

Exemestane is a steroidal aromatase inhibitor used for hormone receptor–positive breast cancer in postmenopausal patients. Many shoppers compare exemestane price and exemestane cost when choosing therapy. It lowers estrogen by irreversibly inactivating aromatase, which helps slow or stop estrogen-dependent tumor growth. Exemestane is available as 25 mg oral tablets and is taken once daily after a meal. YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba, and prescriptions are reviewed by licensed pharmacists before dispensing.

Approved uses include adjuvant treatment after 2–3 years of tamoxifen to complete 5 years of endocrine therapy, and treatment of advanced disease after progression on antiestrogen therapy. It is not indicated for premenopausal patients unless part of a regimen that includes ovarian suppression supervised by an oncology team. We work with vetted, licensed international partner pharmacies to supply authentic brands and generics at fair prices and with a wide selection.

Dosage and Usage

• Standard adult dose: 25 mg by mouth once daily after food. Swallow tablets whole with water.
• Adjuvant setting: often started after 2–3 years of tamoxifen to complete a total of 5 years of endocrine therapy as directed by your clinician.
• Advanced or metastatic disease: 25 mg once daily until disease progression or unacceptable toxicity, as directed by your oncology team.
• Missed dose: take when remembered unless it is close to the next dose. Skip the missed dose if near the next scheduled time. Do not double doses.
• Drug interactions: strong CYP3A4 inducers (for example, rifampin, carbamazepine, phenytoin, St. John’s wort) can reduce exemestane levels. Estrogen-containing products may counteract its effect.
• Monitoring often includes bone mineral density, vitamin D status, lipids, and symptom review. Follow your care plan for any imaging and labs.

• Store at 15–30°C (59–86°F) in a dry place. Keep tablets in the original container with the lid closed.
• Protect from moisture and light. Do not store in a bathroom.
• For travel, carry in hand luggage with your prescription label. Keep below 30°C and away from direct sun or heat sources.
• If traveling across time zones, keep the once-daily schedule consistent with local time.
• Keep out of reach of children and pets.

Benefits and Savings

Exemestane reduces estrogen production by more than 80% in postmenopausal patients. This supports disease control in advanced breast cancer and helps lower recurrence risk in early disease after tamoxifen. The once-daily tablet is convenient. Many people value the predictable dosing and the option to use a generic.

Ordering exemestane online at Canadian prices can bring strong value. Typical savings are 60–80% compared with many US retail prices. Multi-month supplies may lower the per-month cost, and bulk promotions sometimes apply to exemestane for sale. You can set simple reorder reminders so you never run short.

If you prefer the brand, you can compare Aromasin price and pfizer aromasin price against the exemestane generic. Both are the same drug substance and strength. We ship with prompt, express handling to the US, and sensitive items use cold-chain shipping when required.

For seasonal offers, see the exemestane coupon page for current promotions. You may also spot an exemestane discount during limited sales.

Side Effects and Safety

• Hot flashes
• Fatigue
• Joint or muscle pain
• Headache
• Nausea or upset stomach
• Increased sweating
• Trouble sleeping
• Dizziness
• Peripheral swelling

Serious or less common risks can include bone loss and fractures, elevated cholesterol, liver enzyme elevations, depression, carpal tunnel syndrome, and allergic reactions. Avoid use in pregnancy; effective contraception is needed for those at risk of pregnancy. Exemestane is not used with estrogen therapy. Strong CYP3A4 inducers may reduce efficacy; your care team may review alternatives.

Onset Time

Estrogen suppression begins within days. Many patients notice hot flashes or other menopausal-type effects within 1–2 weeks. In metastatic disease, clinical responses are usually assessed after 4–8 weeks, then at regular intervals. In early breast cancer, recurrence risk reduction accumulates over years of consistent therapy.

Bone health changes emerge over months to years, so bone density is often checked at baseline and periodically. Symptom stabilization may continue as your dose remains steady.

Compare With Alternatives

Nonsteroidal aromatase inhibitors such as Anastrozole and letrozole also lower estrogen but bind reversibly. Some patients switch between classes if disease progresses or side effects differ. Choice depends on prior therapy, tolerance, and clinical goals.

Fulvestrant is a selective estrogen receptor degrader (SERD) given by intramuscular injection. It can be used in advanced hormone receptor–positive disease, often after aromatase inhibitors. Route, schedule, and side-effect profiles differ from exemestane.

In HER2-positive disease, targeted agents are added based on receptor status. Therapy such as tucatinib combinations is directed by oncology guidelines and differs from endocrine options.

Combination Therapy

• With ovarian suppression (GnRH agonist) in premenopausal patients as part of specialist-managed regimens.
• With everolimus in certain cases of advanced hormone receptor–positive disease after nonsteroidal AI therapy.
• Sequencing after tamoxifen in early disease to complete 5 years of endocrine therapy.
• Supportive measures for bone health, such as calcium, vitamin D, and bone-strengthening agents, when appropriate.

Patient Suitability and Cost-Saving Tips

Exemestane is intended for postmenopausal patients with hormone receptor–positive breast cancer. It may be used in specific premenopausal cases together with ovarian suppression. It is not a general estrogen blocker for healthy individuals and is not approved for bodybuilding, on cycle use, or coming off exemestane protocols outside oncology care.

Those with severe liver disease, uncontrolled osteoporosis, or hypersensitivity to exemestane should be evaluated carefully. Use is avoided in pregnancy and breastfeeding. Patients with low bone density may need monitoring and preventive measures. Concurrent estrogen products can reduce benefit.

To manage expense, compare exemestane 25 mg cost across package sizes. Choosing the exemestane generic typically lowers the price versus brand. Multi-month orders can reduce shipping fees per month. Reorder reminders help keep therapy on track. If you compare online, look for clear exemestane prescription requirements and transparent fees.

We make it simple to purchase exemestane online with a valid prescription. Many patients compare aromasin online listings, then select the generic for value. If brand is desired, check availability and review pfizer aromasin price data on the product page before placing an order.

Authoritative Sources

Pfizer Aromasin (exemestane) product information

Health Canada Drug Product Database: Exemestane

FDA Prescribing Information for Aromasin (exemestane)

Order Exemestane from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This page is educational and does not replace advice from your healthcare professional. Always follow the guidance of your prescriber and pharmacist.