Fenofibrate, Generic for Tricor® for High Triglycerides

What Fenofibrate Is and How It Works

Fenofibrate is a lipid‑modifying medicine in the fibrate class. It helps lower high triglycerides and can improve mixed dyslipidemia. Common strengths include fenofibrate 160 mg and fenofibrate 145 mg, most often supplied as oral tablets. This fenofibrate generic activates peroxisome proliferator‑activated receptor alpha (PPAR‑α) to increase triglyceride breakdown and raise HDL cholesterol modestly.

YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba, where licensed pharmacists review prescriptions before dispensing, and we offer brand and generic medicines at Canadian prices along with OTC health products.

By reducing very high triglycerides, this triglyceride medication fenofibrate helps lower the risk of pancreatitis. It may be used alone or with a statin when non‑HDL cholesterol remains above target. Fenofibrate tablets are taken by mouth once daily, with or without food depending on the specific formulation. Some legacy products required dosing with meals, while newer nanocrystal products do not. Choline fenofibrate is an alternative salt with similar clinical effects.

Fenofibrate is used for adults diagnosed with primary hypertriglyceridemia or mixed dyslipidemia when diet and exercise alone are not enough. It is not a weight‑loss medicine and is not approved for primary prevention of cardiovascular disease.

Dosage and Usage

• Usual adult dose: 145 mg once daily or 160 mg once daily, depending on product and country labeling.
• Selected products are taken without regard to meals; others should be taken with food. Follow the specific product directions on the label.
• Swallow the fenofibrate 145 mg tablet or fenofibrate 160 mg tablet whole with water. Do not crush or split unless the product label allows it.
• Lipid panels are typically checked 4–8 weeks after starting or changing dose, then periodically to confirm response.
• Missed dose: take when remembered unless it is close to the next dose. Skip the missed dose if near the next scheduled time. Do not double doses.
• If used with a statin, report new muscle pain, weakness, or dark urine promptly.
• Alcohol: discuss fenofibrate and moderate drinking with a clinician, especially if you have liver concerns.

• Store at 15–25°C (59–77°F) in a dry place away from moisture and direct light.
• Keep tablets in the original container with the desiccant, if provided. Close the cap tightly after each use.
• Do not store in a bathroom. Avoid excess heat in cars or near windows.
• When traveling, keep fenofibrate pills in your carry‑on with a copy of your prescription.
• Do not freeze. No refrigeration is needed.
• Check the expiration date before use. Safely discard expired medicine.

Benefits and Savings

Fenofibrate for high triglycerides can reduce triglyceride levels substantially, often within weeks. It can also raise HDL modestly and improve non‑HDL cholesterol. Flexible once‑daily dosing and availability as fenofibrate tablets support adherence. Compared with typical U.S. retail pricing, many customers see 60–80% savings when ordering from Canada.

You can compare fenofibrate price options across strengths. Many choose a 90‑day supply to lower the per‑month fenofibrate cost. Reorder reminders can help you stay on track, and multi‑pack promotions may further reduce your average fenofibrate 145 mg price or fenofibrate 160 mg price.

We partner with licensed, vetted international pharmacies to source authentic brands alongside generics, giving you broad selection and fair pricing.

For extra value, see our fenofibrate coupon page for current offers.

Side Effects and Safety

• Common: stomach pain, nausea, diarrhea, constipation, headache, back pain.
• Lab changes: increases in liver enzymes or creatinine.
• Respiratory or sinus symptoms.
• Rash or photosensitivity.
• Muscle aches.

Serious but less common risks include myopathy or rhabdomyolysis (higher risk with statins or renal impairment), gallstones, pancreatitis, liver injury, and rare venous thromboembolism. Fenofibrate can enhance the effect of warfarin, so INR may need closer monitoring at initiation. Hypoglycemia risk may increase when combined with a sulfonylurea or insulin; dose adjustments to the diabetes medicine may be required.

Onset Time

Initial triglyceride reductions can be seen within 1–2 weeks. Most patients reach a steady response by 4–8 weeks. HDL improvements may take several weeks. Clinicians often recheck a fasting lipid panel after 4–12 weeks to guide any dose or therapy adjustments.

Compare With Alternatives

Statins remain first‑line for lowering LDL cholesterol and reducing cardiovascular events. For patients with mixed dyslipidemia and persistent high triglycerides, fenofibrate can be added to a statin after weighing muscle‑related risks. Options include Rosuvastatin and Lipidil® Ez depending on goals and tolerance.

Marine‑derived omega‑3 products (prescription EPA/DHA or EPA‑only) can lower triglycerides and are often used when triglycerides are very high. Niacin is used less often today due to flushing and limited outcome benefits, but it remains an option for select patients. Choline fenofibrate is a formulation variant designed for once‑daily dosing with food flexibility.

Combination Therapy

• Fenofibrate plus a statin for mixed dyslipidemia when non‑HDL cholesterol remains above target. Monitor for muscle symptoms; consider lower statin doses if risks are high.
• Fenofibrate plus prescription omega‑3 for severe hypertriglyceridemia. Periodic labs guide response and safety.
• Fenofibrate with ezetimibe or bile‑acid sequestrants may be considered in select cases, guided by lipid targets.
• In patients on sulfonylureas or insulin, clinicians may adjust diabetes medication to reduce hypoglycemia risk.

Patient Suitability and Cost-Saving Tips

Candidates include adults with primary hypertriglyceridemia, mixed dyslipidemia, or those at pancreatitis risk from very high triglycerides. It is not usually used in children. Those with active liver disease, severe renal impairment, or pre‑existing gallbladder disease are typically not candidates. Discuss pregnancy and breastfeeding plans before starting therapy.

Fenofibrate prescription products are not interchangeable one‑for‑one across all brands and strengths. Labels differ on whether to take with meals. Your prescriber and pharmacist will match the product to your needs and lab goals.

To save on ongoing therapy, compare fenofibrate 145 mg tablet and fenofibrate 160 mg tablet options for supply sizes. A 90‑day fill can lower the average fenofibrate price. Bulk promotions, when available, may reduce the cost further. Set a reminder before your last refill so you can reorder on time with prompt, express shipping.

Authoritative Sources

Health Canada Drug Product Database (fenofibrate)

FDA Drugs@FDA Database (fenofibrate)

Order fenofibrate from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express shipping.

This content is educational and does not replace advice from your healthcare professional. Always follow your prescriber’s directions and the product label.