Hemangiol® Propranolol Oral Solution for Infantile Hemangioma

What Hemangiol® Is and How It Works

Hemangiol® is a propranolol oral solution used to treat proliferating infantile hemangiomas that need systemic therapy. It contains propranolol at 3.75 mg/mL. The medicine narrows small blood vessels, slows abnormal vessel growth, and encourages regression of the lesion. Families often compare Hemangiol price options when planning therapy, including hemangiol price without insurance for out-of-pocket budgeting. For full prescribing details, refer to the hemangiol spc or official monograph.

YouDrugstore is a licensed Canadian pharmacy based in Manitoba, where licensed pharmacists review prescriptions before dispensing. We offer brand and generic medicines at Canadian prices, plus OTC health products, with online ordering and customer-service chat during posted hours.

Propranolol is a non-selective beta-blocker. It blocks β1 and β2 receptors, which reduces blood flow within the hemangioma and influences growth signals such as VEGF and bFGF. Treatment is oral and given twice daily during or right after feeding. Many courses last about six months, and some continue longer based on clinical progress.

Dosage and Usage

• Initiation: typical starting dose is 1 mg/kg/day divided into two doses. After one week, increase to 2 mg/kg/day. After another week, increase to 3 mg/kg/day if tolerated. The solution is 3.75 mg/mL (also written as hemangiol 3.75 mg ml or hemangiol 3 75 mg ml).
• Give each dose during or immediately after a feeding. This lowers the risk of low blood sugar.
• Measure doses with the supplied oral syringe. Do not use kitchen spoons.
• Shake the bottle gently before measuring. Administer the solution (hemangiol sirup) slowly into the child’s cheek.
• If the child is not feeding well, vomiting, or ill with poor intake, hold doses and contact the prescriber for advice.
• Missed dose: if remembered within a few hours, give with feeding. If close to the next dose, skip the missed dose. Do not double up.
• Do not stop the medicine suddenly unless told by the prescriber. Follow the tapering plan if one is provided.

• Storage: keep at 20–25°C (68–77°F). Short excursions 15–30°C (59–86°F) are usually acceptable. Do not freeze.
• Keep the bottle tightly closed and in the original carton to protect from light.
• Record the opening date. Discard any remaining solution two months after first opening.
• Travel: pack in carry-on baggage. Keep upright and out of heat. Do not leave in a parked car.
• Use the cap and oral syringe supplied with the bottle. Rinse and air-dry the syringe after use.

Benefits and Savings

Propranolol therapy improves size, color, and thickness of infantile hemangiomas. Ulcerated lesions often heal faster, which can reduce pain and bleeding. Early control may lower the need for surgery or lengthy dressings. Oral solution dosing is weight-based and adjusted as the child grows, which helps keep treatment consistent.

Ordering hemangiol online from a licensed Canadian pharmacy can lower total costs. Many patients see 60–80% savings compared with typical U.S. retail pricing. Pricing is transparent for those paying hemangiol cost out of pocket, including patients purchasing hemangiol without insurance. Multi-month supplies and bulk promotions can reduce per-month costs.

We work with licensed, vetted international partner pharmacies when needed to maintain supply of authentic brand medicines, broad choice, and affordable pricing.

Looking for added value? Check our promotions page for a hemangiol coupon at https://youdrugstore.com/promotions.

Side Effects and Safety

• Common: sleep changes, irritability, cool hands or feet, diarrhea, constipation, vomiting, reduced appetite.
• Cardiovascular: low heart rate, low blood pressure, fatigue.
• Respiratory: nasal congestion or wheeze in sensitive children.
• Metabolic: low blood sugar, especially with poor feeding or prolonged fasting.
• Skin: mild rash or flushing.

Serious risks are uncommon but include severe hypoglycemia (which may cause seizures), bronchospasm, significant bradycardia, hypotension, and heart block. Beta-blockers can mask signs of low blood sugar. Risk of hypoglycemia increases if combined with insulin or sulfonylureas. Use is contraindicated in asthma or active bronchospasm, uncompensated heart failure, second- or third-degree AV block, severe bradycardia, and known hypersensitivity. Children with PHACE syndrome or cerebrovascular anomalies need careful specialist evaluation before starting propranolol.

Onset Time

Many lesions begin to soften or fade within 1–2 weeks after starting propranolol. Ulcer pain and drainage may improve within 2–4 weeks. Visible color change and flattening often continue over the first 4–8 weeks as dosing stabilizes. The full response evolves over months; typical treatment lasts about six months, with some courses extended based on clinical need.

Compare With Alternatives

Topical timolol may help small, superficial hemangiomas. It is not a substitute for systemic therapy in larger, deeper, or function-threatening lesions. Propranolol oral solution remains the preferred option when systemic treatment is indicated.

Atenolol is used off-label in select cases, particularly when bronchospasm risk is a concern. Evidence is growing, but propranolol has the most robust data and a licensed pediatric formulation.

Compounded propranolol solutions are an alternative where licensed products are unavailable. Hemangiol® provides a standardized concentration, pediatric-friendly flavoring, and stability data supported by the manufacturer and regulators.

Combination Therapy

• Oral propranolol plus topical timolol for mixed lesions with a superficial component.
• Propranolol with wound care for ulcerated areas; add antibiotics if infection is confirmed.
• Propranolol followed by laser or surgery for residual telangiectasia or fibrofatty tissue after involution.
• When combined with agents that lower glucose, prescribers may adjust doses to reduce hypoglycemia risk.

Patient Suitability and Cost-Saving Tips

Candidates include infants with hemangiomas that impair function (vision, breathing, feeding), ulcerate, or risk scarring or disfigurement. Therapy is usually started in early infancy. Supervision by clinicians experienced in infantile hemangioma is essential. Baseline heart rate and blood pressure are assessed, and some children require monitored initiation.

Propranolol is not appropriate in asthma, active bronchospasm, severe bradycardia, second- or third-degree heart block, decompensated heart failure, or in children with known hypersensitivity. Caution is needed with PHACE syndrome or cerebrovascular anomalies. Dose changes follow weight changes or tolerability.

To manage costs, consider larger fills when clinically appropriate, because multi-month supplies may reduce monthly spend. Set reorder reminders so therapy is not interrupted. Pricing is clear for those paying hemangiol cash price, and many families choose hemangiol cost without insurance when comparing international pharmacy options.

Authoritative Sources

European Medicines Agency: Hemangiol overview and SmPC

FDA Prescribing Information: Hemangeol (propranolol oral solution)

Manufacturer Product Page: Hemangiol (propranolol) oral solution

Order Hemangiol® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express shipping.

This page is educational and does not replace advice from your child’s healthcare professional. Always follow your prescriber’s instructions for dosing, monitoring, and follow-up.