Humira® (adalimumab) Prefilled Pen and Syringe for Autoimmune Conditions

What Humira® Is and How It Works

Humira® (adalimumab) is a prescription biologic that targets tumor necrosis factor-alpha (TNF-α). It treats several autoimmune conditions, including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, plaque psoriasis, Crohn’s disease, ulcerative colitis, juvenile idiopathic arthritis, and hidradenitis suppurativa. It is given as a subcutaneous injection using a prefilled pen or syringe. Dosing schedules vary by condition, with maintenance dosing often every other week. Many people compare humira cost per month without insurance when planning long-term therapy and budgeting.

YouDrugstore is a licensed Canadian pharmacy based in Manitoba. Our pharmacists review prescriptions before dispensing and support safe use. We offer brand and generic medicines at Canadian prices, and you can order online with friendly customer-service chat during posted office hours. We also carry OTC health products for everyday care.

We work with licensed, vetted partner pharmacies internationally to source authentic brand medications, keeping a wide selection available at affordable pricing.

Dosage and Usage

Dosing depends on the condition and patient factors. Follow your prescriber’s regimen and the product instructions. Common adult maintenance dosing for arthritis is 40 mg every other week. Crohn’s disease and ulcerative colitis often start with higher induction doses, then step down to maintenance dosing. Hidradenitis suppurativa and plaque psoriasis may use different loading and maintenance schedules.

• Initiation: Many indications start with a loading dose (for example, 160 mg, then 80 mg two weeks later), then move to 40 mg every other week. Some patients need weekly dosing.
• Administration: Inject subcutaneously in the thigh or abdomen. Rotate sites and avoid red, bruised, or tender skin.
• Missed dose: If a dose is missed, take it when remembered and resume the original schedule. Do not double up.
• Storage: Store pens and syringes in the refrigerator at 2–8°C (36–46°F). Do not freeze.
• Room temperature window: If needed, keep at room temperature (up to 25°C/77°F) for a single period up to 14 days. Do not return to the fridge. Discard if unused after that window.
• Travel: Keep in the original carton. Use a cool pack during travel. Protect from light and heat.

Benefits and Savings

Humira® reduces inflammation by blocking TNF-α. Patients often see less joint pain and swelling in rheumatoid arthritis and psoriatic arthritis. It can improve skin clearance in plaque psoriasis. In Crohn’s disease and ulcerative colitis, it can induce and maintain remission. Many patients report better function and quality of life with steady use.

Buying from a Canadian pharmacy can lower costs. Typical savings are 60–80% compared with many US retail prices. We support budgeting with multi-month options and transparent pricing. If paying out of pocket, the cost can still compare favorably without insurance when ordered through our pharmacy model. Customer-service chat can help with ordering questions during posted hours.

Side Effects and Safety

All biologics carry risks and benefits. Review safety information with your prescriber and read the package materials before use.

• Common: Injection site redness or pain, headache, nausea, mild rash, sinusitis, and upper respiratory infections.
• Less common: Elevated liver enzymes, dizziness, abdominal pain, and fatigue.
• Serious: Severe infections (including TB or opportunistic infections), reactivation of hepatitis B, malignancy, demyelinating disease, new or worsening heart failure, severe allergic reactions, blood disorders, and lupus-like syndrome.

Screening for latent tuberculosis is standard before starting therapy. Live vaccines are generally avoided during treatment. Tell your health provider about current infections, planned surgery, or if pregnant or breastfeeding.

Onset Time

Onset varies by condition. Some patients with arthritis feel improvement in 1–2 weeks. Skin symptoms may improve over several weeks. Inflammatory bowel disease responses can take 2–8 weeks. A full assessment often occurs by 12 weeks, and treatment is adjusted based on response and tolerability.

Compare With Alternatives

Several biologics and biosimilars treat similar conditions. Adalimumab biosimilars offer comparable efficacy and safety to Humira® in most indications. A relevant option available here is Rymti® Pre Filled Injection, which contains adalimumab.

Etanercept is another anti-TNF agent used for arthritis and psoriasis. It has a different structure and dosing schedule. You can compare features and formats with Enbrel® Pre Filled Syringe or the Enbrel® Pre Filled Sureclick Auto Injector. Your prescriber can help match the medicine to your diagnosis and goals.

Other options in certain cases include infliximab, ustekinumab, secukinumab, or vedolizumab. They differ in mechanism, route, and dosing frequency. Prior response, comorbidities, and lab results often guide selection.

Combination Therapy

Many patients use adalimumab alone. Some rheumatoid arthritis patients take it with methotrexate to improve durability and reduce antibody formation. Folic acid is often paired with methotrexate. Use with other biologics or targeted synthetic DMARDs is generally avoided due to overlapping immunosuppression. Live vaccines are not recommended during treatment. Coordinate vaccines, lab monitoring, and any surgery planning with your care team.

Patient Suitability and Cost-Saving Tips

People with active serious infections, untreated latent TB, or moderate to severe heart failure may not be good candidates. Use caution with demyelinating disease, prior malignancy, chronic hepatitis B, or significant cytopenias. Pediatric dosing and safety need specialist oversight. Discuss pregnancy and breastfeeding plans with your prescriber.

To reduce costs, consider a multi-month supply when feasible, which can lower the per-month expense. Sign up for reorder reminders so refills arrive before you run out. If paying out of pocket, comparing humira cost per month without insurance across sources can help you plan your budget and avoid gaps in therapy.

For patients with Rheumatoid Arthritis or Crohn’s Disease, steady access matters for control of flares. You can learn about medicine classes in our article Arthritis Drugs and discuss options with your prescriber.

For current savings and bulk options, see promotions, including humira manufacturer coupon, on our promotions page.

Authoritative Sources

Review official prescribing information for complete details. See the manufacturer’s Humira resources on the Humira website. In Canada, consult the Health Canada Drug Product Database entry for HUMIRA. US clinicians can review the FDA Prescribing Information for Humira.

You can order Humira® from YouDrugstore with pharmacist-reviewed prescriptions and support from our team. We ship with prompt, express, cold-chain shipping to protect product quality from our Manitoba pharmacy to the US.

Disclaimer: This page provides general information and is not a substitute for medical advice. Always follow your prescriber’s directions and the product’s labeling. Seek medical help right away if you experience signs of a severe reaction or infection.