Hyzaar® (losartan/hydrochlorothiazide) tablets for high blood pressure

What Hyzaar Is and How It Works

Hyzaar® is a prescription combination of losartan and hydrochlorothiazide (HCTZ) used to treat high blood pressure. It joins an angiotensin II receptor blocker with a thiazide diuretic to lower blood pressure through two pathways. Tablets are taken by mouth once daily. Common strengths include 50/12.5 mg, 100/12.5 mg, and hyzaar 100 25 mg. You can order hyzaar online from YouDrugstore, a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing, and customer-service chat is available during posted office hours.

Losartan relaxes blood vessels by blocking angiotensin II. HCTZ helps the body remove extra salt and water. Using both agents in one tablet can improve control when one medicine alone is not enough. We work with licensed, vetted partner pharmacies internationally to expand supply while keeping authentic brand options available at competitive prices.

Hyzaar® is indicated for adults with hypertension. Lowering blood pressure reduces the risk of stroke and other cardiovascular events. Your order may include brand or generic hyzaar tablets at Canadian prices, and we also carry OTC health products for heart health.

Dosage and Usage

Follow your prescriber’s directions and label instructions.

• Typical starting dose: 50/12.5 mg once daily.
• If needed after 2–4 weeks, the dose may increase to 100/12.5 mg once daily.
• If further control is needed, 100/25 mg once daily may be used. This is the usual maximum dose.
• Take at the same time each day, with or without food.
• Do not split tablets unless scored and your prescriber says it is appropriate.
• Missed dose: take it when remembered the same day. Skip if it is close to the next dose. Do not double doses.

Monitoring may include blood pressure, kidney function, and electrolytes such as potassium and sodium. Dose adjustments may be needed for those with liver or kidney impairment. Older adults may start at the lower strength. Water loss can increase urination; take the dose earlier in the day if night-time bathroom trips are a concern.

• Storage: store at 20–25°C (68–77°F) in a dry place. Keep tablets in the original container with the label.
• Avoid heat, moisture, and direct sunlight. Do not store in the bathroom.
• Travel: carry your medication in your hand luggage in the original labeled container.
• Use a pill organizer or set reminders to help keep a steady schedule.

Benefits and Savings

Hyzaar® combines two medicines in one daily tablet. This can simplify therapy and improve adherence. The ARB and thiazide work together to lower blood pressure more than either agent alone. Better control can help reduce stroke and heart complications linked to hypertension. Many patients appreciate the once-daily routine and the availability of multiple strengths.

Ordering from YouDrugstore gives you access to Canadian pricing and support from licensed pharmacists. You may see 60–80% savings versus typical US prices. You can track your hyzaar cost per month and choose multi-month quantities to lower per-unit pricing.

Side Effects and Safety

• Common: dizziness, headache, lightheadedness, fatigue, increased urination, muscle cramps, nausea.
• Electrolyte changes: low sodium or potassium changes may occur. Your prescriber may check blood tests.
• Metabolic effects: HCTZ may raise uric acid (gout risk) or blood sugar in some patients.
• Photosensitivity: skin may burn more easily in the sun; use sun protection.
• Serious: fainting, very slow or fast heartbeat, severe dehydration, eye pain or vision changes (rare angle-closure glaucoma), kidney problems, or signs of an allergic reaction (swelling of face, lips, tongue, or throat). Seek urgent care if these occur.
• Pregnancy: do not use during pregnancy. ARBs can harm or end a pregnancy. Tell your prescriber if you become pregnant.
• Breastfeeding: discuss risks and benefits with your healthcare provider.
• Drug interactions: NSAIDs may reduce effect on blood pressure and kidney function. Lithium levels may rise. Other blood pressure medicines, diuretics, or alcohol can increase dizziness. Ask your pharmacist to review your medication list.

Onset Time

Many patients see a drop in blood pressure within one week. The full effect often appears after two to four weeks at a stable dose. Your prescriber may adjust the dose based on home or clinic readings over time.

Compare With Alternatives

Losartan alone may suit patients needing a single agent, especially if diuretics are not appropriate. Adding HCTZ in a fixed-dose combination like Hyzaar® can improve convenience compared to taking two separate tablets.

Other ARB/thiazide combinations include valsartan/HCTZ and olmesartan/HCTZ. ACE inhibitor combinations, such as lisinopril/HCTZ, are alternatives when ARBs are not selected. Patients sensitive to cough from ACE inhibitors often prefer ARBs.

For those needing the higher diuretic strength, you can review Hyzaar® Ds on our site, which corresponds to 100/25 mg. Remember that your prescriber chooses the strength based on response and lab results.

Combination Therapy

Hypertension control often requires more than one class. Hyzaar® may be used with calcium channel blockers, beta blockers, or other agents when needed. Cardiovascular risk reduction also includes lipid management, diet, and exercise. If cholesterol is elevated, your prescriber may choose a statin. You can compare options like Crestor® if a statin is prescribed for you.

Patient Suitability and Cost-Saving Tips

Hyzaar® suits adults who need two agents to control blood pressure or who are already taking losartan and HCTZ separately. It is not for use during pregnancy. Caution is necessary with severe kidney disease, significant liver impairment, gout, or a history of thiazide sensitivity. Review all medical conditions with your prescriber.

To manage costs, consider the generic for hyzaar when appropriate. Ordering a 90-day supply can reduce the per-month price, and our reorder reminders help you stay on schedule. See current hyzaar discount opportunities and bulk options on our Promotions page. You can also explore our condition pages for High Blood Pressure and Stroke Prevention to learn more about treatment goals. For general heart health reading, see 10 Interesting Facts About Your Heart.

Authoritative Sources

For detailed prescribing information, review the FDA label for losartan/hydrochlorothiazide HYZAAR Prescribing Information (FDA) and the Health Canada Drug Product Database entry for this combination Health Canada Drug Product Database. You may also consult the manufacturer’s professional resources if available in your region.

YouDrugstore is a licensed Canadian pharmacy that meets Canadian pharmacy standards. Our pharmacists review every prescription before dispensing. If you have order or shipping questions, our customer-service chat is available during posted office hours. We offer prompt, express, cold-chain shipping to the US when needed.

This content is for general information. It does not replace advice from your own healthcare provider. Always follow your prescriber’s directions and your medication label. Keep medicines out of children’s reach.