Inlyta® (axitinib) Tablets for Advanced Kidney Cancer

What Inlyta Is and How It Works

Inlyta® (axitinib) is an oral tyrosine kinase inhibitor used for advanced renal cell carcinoma (kidney cancer). It targets vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3) to slow blood vessel growth that feeds tumors. The usual strength is Inlyta 5 mg, taken twice daily. Many people explore options for inlyta without insurance to manage ongoing treatment costs. YouDrugstore is a licensed Canadian pharmacy based in Manitoba, meeting Canadian pharmacy standards. Our pharmacists review prescriptions before dispensing, and you can order online with friendly customer-service chat during posted office hours.

We work with licensed, vetted partner pharmacies internationally to source authentic brand medicines, offering a broad selection at fair, affordable pricing. Inlyta® is indicated for adults with advanced kidney cancer, either after prior therapy or as part of select combination regimens. Tablets are film-coated and taken by mouth. Dosing is typically continuous, in 12-hour intervals, unless a clinician pauses or adjusts the dose due to side effects or interactions.

Dosage and Usage

The usual starting dose is 5 mg by mouth twice daily, about 12 hours apart. It can be taken with or without food. Swallow tablets whole with water.

• Start at 5 mg twice daily unless told otherwise by your clinician.
• Dose may increase to 7 mg twice daily, then 10 mg twice daily, if tolerated.
• Dose may decrease to 3 mg or 2 mg twice daily for side effects.
• Avoid grapefruit or grapefruit juice.
• If you miss a dose and it is almost time for the next dose, skip the missed dose.
• Do not take extra tablets to make up for a missed dose.
• If you vomit a dose, do not take an extra tablet; resume at the next scheduled time.

Drug interactions are common. Strong CYP3A4 inhibitors (such as clarithromycin or certain azole antifungals) can raise axitinib levels, and strong CYP3A4 inducers (such as rifampin) can lower them. Blood pressure often rises early in therapy, and monitoring is standard.

• Store at 20-25°C (68-77°F) in the original container.
• Keep tablets dry and away from moisture and light.
• When you travel, carry Inlyta® in your hand luggage with a copy of your prescription.
• Use a pill organizer only if it keeps tablets protected and labeled.

Benefits and Savings

In clinical use, axitinib helps slow disease progression and can shrink tumors in some patients with advanced kidney cancer. It offers an oral option with steady, twice-daily dosing. Many treatment plans use it after prior therapy, and quality-of-life measures may improve when disease control is achieved.

YouDrugstore offers Canadian pricing on brand oncology medicines. Typical savings are 60-80% compared with common US retail prices. We support US shipping and make reorders simple with reminders. Multi-month supplies may lower the per-month cost. If you are comparing inlyta cost without insurance, our team can help you review current pricing and supply options.

Side Effects and Safety

Side effects vary. Your care team monitors labs, blood pressure, and symptoms and may adjust dosing. Common effects often appear in the first weeks, and some improve with supportive care.

• Common: diarrhea, fatigue, nausea, decreased appetite, weight loss, vomiting, constipation, abdominal pain.
• Skin: hand-foot syndrome (palmar-plantar erythrodysesthesia), rash, dry skin.
• Blood pressure: hypertension and headache.
• Endocrine: hypothyroidism.
• Voice: hoarseness (dysphonia).

• Serious: severe hypertension or hypertensive crisis.
• Bleeding: hemorrhage, including GI bleeding.
• Cardiovascular: heart failure, arterial or venous thromboembolic events.
• Renal: proteinuria and rare kidney impairment.
• GI: perforation or fistula, and rare pancreatitis.
• Neurologic: reversible posterior leukoencephalopathy syndrome (RPLS/PRES).
• Hepatic: elevated liver enzymes and rare hepatic failure.
• Wound healing complications; stop before major surgery as advised by your clinician.

Use effective contraception during treatment and after stopping as advised. Avoid breastfeeding during therapy. People with uncontrolled blood pressure, recent bleeding, or high cardiovascular risk may need closer monitoring or alternative therapy. Report new or worsening symptoms promptly to your oncology team.

Onset Time

Pharmacologic effects on VEGFR occur quickly, and blood pressure changes can appear within days to weeks. Radiographic tumor response is often assessed after several weeks on therapy. Many patients have the first imaging recheck at 6-12 weeks, though schedules vary by clinic and disease status.

Compare With Alternatives

First-line and later-line kidney cancer regimens include other VEGFR inhibitors and immunotherapy combinations. Sunitinib and pazopanib are earlier-generation VEGFR TKIs used for advanced renal cell carcinoma. Cabozantinib targets multiple kinases and is used across lines of therapy, including post-immunotherapy settings.

Combination immunotherapy has become standard in many cases. Avelumab plus axitinib is one option; you can review Bavencio® to learn more about that checkpoint inhibitor. Pembrolizumab plus axitinib is another widely used combination. Choice depends on risk category, prior treatment, comorbidities, and tolerability considerations discussed with your oncology team.

New regimens continue to evolve. If you have a different cancer type, therapy will differ. You can explore our Cancer category for other oncology medicines available through our pharmacy.

Combination Therapy

Axitinib may be prescribed alone or with an immune checkpoint inhibitor. When combined, side effect profiles can overlap. Blood pressure, liver enzymes, thyroid function, and immune-related adverse events require close monitoring. Your oncology team coordinates scheduling, imaging, and lab checks. Dose modifications of axitinib are common and help keep therapy on track when side effects arise.

Patient Suitability and Cost-Saving Tips

Inlyta® is suited for adults with advanced renal cell carcinoma as directed by an oncologist. Suitability depends on prior therapy, blood pressure control, bleeding risk, liver function, and potential interactions. Those with recent significant bleeding, uncontrolled hypertension, or upcoming major surgery may need alternative timing or options. Always keep your full medication list current with your care team.

You can reduce costs by selecting longer supplies when appropriate, which may lower the per-month price. We offer reorder reminders so you can stay on schedule. For current deals, see our inlyta coupon options and bulk promotions. Our team can explain pricing details and help compare strengths and pack sizes.

To learn practical side effect tips used in oncology care, you may find Common Darzalex Side Effects And Tips To Manage Them useful, and for targeted therapy basics, see Understanding Calquence Medication For Cancer Treatment. These resources discuss general concepts that often apply across cancer treatments.

Authoritative Sources

For full prescribing details, review the Pfizer Inlyta product page, the Health Canada Drug Product Database entry, and the FDA Prescribing Information.

YouDrugstore offers brand oncology medicines at Canadian prices with pharmacist review of prescriptions. Order online or by phone during posted hours, and our team will help with practical questions. We ship to the US with prompt, express, cold-chain shipping as required.

This content is for general information. It does not replace medical advice, diagnosis, or treatment. Use only as directed by your prescriber. Always read the patient information that comes with your medicine and speak with your healthcare professional about your specific situation.