Avalide® Tablets for Hypertension

This combination medicine lowers blood pressure in adults with hypertension. Learn how it works, how to take it, and ways to access Irbesartan HCTZ without insurance, with US delivery from Canada.

What Avalide Is and How It Works

Avalide® contains irbesartan, an angiotensin receptor blocker, and hydrochlorothiazide, a thiazide diuretic. Together, they help relax blood vessels and support the kidneys in removing extra salt and water, which can reduce blood pressure. Irbesartan HCTZ tablets combine these two agents in fixed doses for convenient once-daily use. The treatment may be used when a single medicine does not provide enough control or when a prescriber prefers a fixed-dose option.

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Irbesartan blocks the angiotensin II receptor to lower vascular resistance. Hydrochlorothiazide helps reduce fluid volume while supporting blood pressure control. This combination can be used alongside lifestyle measures like reduced sodium intake and regular physical activity, as directed by your healthcare professional.

Who It’s For

This medicine is indicated for adults with hypertension who may benefit from a fixed-dose combination. Avalide tablets are considered when the individual components are appropriate and a single pill may help adherence. It is not recommended during pregnancy and should be avoided if you have anuria or known hypersensitivity to any component. People with significant kidney or liver problems require careful evaluation by their prescriber. Learn more about the condition at our Hypertension category page.

Dosage and Usage

The treatment is usually taken once daily, at the same time each day. Some adults start with Irbesartan HCT once daily as directed by the prescriber. It can be taken with or without food. Swallow tablets whole with water. Do not change your schedule without medical guidance. If your clinician adjusts therapy, follow the prescription label closely. Home blood pressure checks can help track response between visits.

General administration tips:

• Take at a consistent time each day.
• If dizziness occurs, rise slowly from sitting or lying positions.
• Avoid dehydration; discuss sick-day rules with your clinician.
• Do not stop suddenly without professional advice.

Strengths and Forms

This therapy is supplied as oral tablets. Irbesartan/Hydrochlorothiazide tablets are available in multiple fixed-dose strengths. Common strengths include 150/12.5 mg, 300/12.5 mg, and 300/25 mg. Availability may vary by manufacturer and stock.

Missed Dose and Timing

If you miss a dose, take it when you remember the same day. If it is almost time for the next dose, skip the missed dose and resume your usual schedule. Do not double up to make up for a missed dose. Set reminders or use a pill organizer if timing is challenging.

Storage and Travel Basics

Store tablets at room temperature in a dry place away from moisture. Keep them in the original, labeled container with the child-resistant cap closed. For travel, pack your medicine in your carry-on, along with a copy of your prescription and your prescriber’s details. Avoid storing tablets in hot vehicles or bathrooms with high humidity. For long trips, bring extra doses and a simple schedule card to stay on track.

Benefits

This combination can simplify treatment by pairing two mechanisms in one pill. Once-daily dosing may help routine use. The therapy can be combined with lifestyle measures and other medicines when a prescriber decides more support is needed. Fixed-dose options may reduce the number of separate prescriptions to manage.

Side Effects and Safety

• Dizziness or lightheadedness, especially when starting
• Headache or fatigue
• Increased urination
• Upset stomach or diarrhea
• Muscle cramps
• Skin sensitivity to sunlight

Serious but less common risks can include low blood pressure, changes in kidney function, and electrolyte imbalances such as low sodium or potassium changes. Rare reactions like angioedema require urgent care. This class can raise uric acid; gout may occur in susceptible individuals. If you take insulin or sulfonylureas, discuss low blood sugar precautions with your prescriber. Seek medical attention if you experience facial swelling, breathing difficulty, fainting, or eye pain with vision changes.

Drug Interactions and Cautions

Tell your clinician about all medicines and supplements. Notable interactions may include:

• Lithium, due to risk of increased levels
• NSAIDs, which may lessen blood pressure control and affect kidneys
• Other blood pressure medicines, which can add to effects
• Potassium supplements or potassium-sparing diuretics
• Bile acid resins, which can affect thiazide absorption
• Aliskiren in people with diabetes

Alcohol can enhance dizziness. Because thiazides may increase sun sensitivity, consider protective clothing and sunscreen. Learn more about combination therapies in our article Hyzaar Uses.

What to Expect Over Time

Blood pressure reduction is typically gradual. Many people notice better readings with consistent daily use and lifestyle changes like lower sodium intake and regular movement. Your prescriber may adjust therapy to reach target goals. Keep routine appointments for monitoring and lab checks when recommended. If you track home readings, bring your log to visits for review. For more background on managing the condition, see Treat Hypertension.

Compare With Alternatives

Other options in this space include an angiotensin receptor blocker alone, or an ACE inhibitor with a thiazide. Examples we carry include Losartan and the ACE/thiazide combination Lisinopril HCTZ. Your prescriber will consider kidney function, potassium trends, cough history, and other factors when choosing a regimen.

Pricing and Access

Compare Irbesartan HCTZ Canadian pricing and see current options on this page. We provide transparent listings so you can review available manufacturers and pack sizes before starting checkout. This therapy can be a cost-conscious choice for many people using a prescription. If you’re looking for deals, visit our Promotions page for current offers. Encrypted checkout and clear order status updates support a smooth experience. Ships from Canada to US.

Availability and Substitutions

Supply may vary by strength and manufacturer. If your preferred option is unavailable, your prescriber may recommend an alternative strength or a different class. Pharmacists may reach out if clarification is needed to ensure the correct product is dispensed. Category pages like Cardiovascular can help you explore related therapies.

Patient Suitability and Cost-Saving Tips

This medicine may not be right if you are pregnant or planning pregnancy. Avoid it if you have anuria or a known reaction to sulfonamide-derived diuretics. People with severe liver or kidney disease need careful monitoring. Discuss hydration, sick-day guidance, and lab follow-up. To manage costs, consider multi-month fills when appropriate, set refill reminders, and keep an updated medication list to avoid unnecessary duplication.

Questions to Ask Your Clinician

• Is this combination appropriate for my blood pressure goals?
• How should I monitor at home, and how often?
• What labs will you check and when?
• Could this medicine affect my potassium, sodium, or uric acid?
• What should I do if I feel lightheaded?
• Are there lifestyle steps that would help this treatment work better?
• What alternatives should we consider if targets are not met?

Authoritative Sources

FDA DailyMed official labeling repository

FDA Drugs regulatory information

Health Canada DPD product database

Ready when your prescription is? Place your order with prompt, express shipping and US shipping from Canada. Information here is educational and not a substitute for your clinician’s advice or the official label.