Jentadueto® Tablets for Type 2 Diabetes

What Jentadueto® Is and How It Works

Jentadueto is a prescription combination tablet that contains linagliptin and metformin. It helps adults with type 2 diabetes manage blood sugar alongside diet and activity. We support US delivery from Canada, and you will also find guidance for paying without insurance.

YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

Linagliptin belongs to a class called DPP-4 inhibitors. It helps raise incretin levels, which can increase insulin release and reduce glucagon after meals. Metformin lowers glucose production in the liver, improves insulin sensitivity, and reduces absorption of sugar in the gut. Together, the two medicines act through complementary pathways to help improve glycemic control in adults with Type 2 Diabetes.

Who It’s For

This medicine is used to improve blood sugar control in adults with type 2 diabetes, alongside diet and exercise. It is not for type 1 diabetes or diabetic ketoacidosis. People with severe kidney impairment should not use metformin-containing products. Those with liver disease, hypoxia, heavy alcohol use, or a history of pancreatitis should discuss risks carefully with a clinician. Safety in children has not been established. If you are pregnant, planning pregnancy, or breastfeeding, ask your prescriber whether another therapy may be more appropriate.

Dosage and Usage

Follow your prescriber’s instructions and the official label. Immediate-release tablets are generally taken twice daily with meals. Extended-release tablets are usually taken once daily with a meal. Swallow tablets whole with water. Do not crush or split extended-release tablets.

Your starting schedule often depends on your current therapy. If you are switching from metformin alone, your clinician may select a dose that matches your existing metformin amount. If you are adding this treatment to insulin or a sulfonylurea, your prescriber may advise closer glucose monitoring to reduce low blood sugar risk. Kidney function is typically assessed before starting and periodically thereafter.

Take doses at the same times each day to support steady control. If stomach upset occurs, taking tablets with food can help. Review how this therapy fits with your meal plan and activity. For background on the metformin component, see our article Metformin And Its Role.

Strengths and Forms

Tablets are available as immediate-release combinations such as 2.5/500 mg, 2.5/850 mg, and 2.5/1000 mg, typically taken twice daily. Extended-release tablets are available in once-daily options, such as 2.5/1000 mg and 5/1000 mg. Availability can vary by manufacturer and market. Your prescriber will select a regimen suited to your glycemic targets and tolerability.

If you prefer fewer daily doses, extended-release options may be considered. Keep in mind that formulations are not interchangeable tablet for tablet. Speak with your healthcare professional before making any changes.

Missed Dose and Timing

If you miss a dose, take it when you remember, unless it is close to the time for your next dose. If it is nearly time for the next dose, skip the missed dose and resume your regular schedule. Do not take two doses at once. For extended-release, take with a meal and do not split the tablet. If you frequently forget, ask about strategies like reminders or aligning dosing with routine meals.

Storage and Travel Basics

Store tablets at room temperature in a dry place, away from heat and moisture. Keep the bottle tightly closed and out of reach of children. Use the original labeled container when possible. When traveling, carry your medicine in your hand luggage with a copy of your prescription. Keep doses with your daily essentials to avoid missed tablets across time zones. Do not store tablets in a bathroom or a hot car. If you are stopped at security, present your labeled container and prescription.

Benefits

This combination targets glucose from two angles. The DPP-4 inhibitor component acts around meals to help increase insulin when glucose is higher. The biguanide component improves insulin sensitivity and reduces liver glucose output, which can benefit fasting and post-meal readings. The once-daily extended-release option can reduce pill burden for some people. When used without insulin or a sulfonylurea, the risk of low blood sugar is generally lower than with some other classes.

Side Effects and Safety

• Digestive changes: diarrhea, nausea, upset stomach
• Upper respiratory symptoms: sore throat, runny nose
• Headache: usually mild and transient
• Back or joint pain: typically mild

Serious effects are uncommon but need urgent care. Lactic acidosis is a rare medical emergency linked to metformin, with symptoms such as unusual muscle pain, severe tiredness, slow heartbeat, and breathing changes. Pancreatitis has been reported with DPP-4 inhibitors; severe abdominal pain that may radiate to the back needs evaluation. Severe allergic reactions, including angioedema and skin blistering, can occur. Very severe joint pain and bullous pemphigoid have been reported. Hypoglycemia can occur when combined with insulin or sulfonylureas. Your clinician can explain the signs and when to seek help.

Drug Interactions and Cautions

Tell your healthcare professional about all medicines, vitamins, and supplements you use. Iodinated contrast procedures may require holding metformin before and after the study per label guidance. Carbonic anhydrase inhibitors like topiramate can increase the risk of lactic acidosis. Alcohol misuse raises risk for lactic acidosis and low blood sugar. Strong inducers such as rifampin may reduce exposure to the DPP-4 inhibitor component. Insulin and sulfonylureas can increase low blood sugar risk when used together with this medicine.

What to Expect Over Time

Many people see steadier fasting and after-meal readings with consistent use. Digestive side effects often lessen after the first days or weeks. Regular meals, hydration, and taking tablets with food can improve comfort. Your prescriber will usually check A1C every few months and kidney function periodically. Over time, you may review dose, formulation, or timing as your care plan evolves. Healthy eating, activity, and adherence remain central to reaching your targets. If you are comparing formulation options, keep in mind that Linagliptin metformin XR price varies by strength and pack size.

Compare With Alternatives

Other approved combinations may fit your plan. Saxagliptin plus metformin is available as Komboglyze®, which pairs a DPP-4 inhibitor with metformin like this medicine does. Canagliflozin plus metformin is available as Invokamet®, combining an SGLT2 inhibitor with metformin. Each option has distinct considerations for kidney function, side effects, and dosing. Your prescriber can help decide which therapy aligns with your goals and medical history.

Pricing and Access

We list current options so you can review Jentadueto price alongside other formats. You can also compare Linagliptin metformin price if you are evaluating class alternatives. To look for seasonal offers, visit our Promotions page. Orders are filled by our Canadian pharmacy and Ships from Canada to US. Your order is processed through encrypted checkout, and your prescription is required and verified before dispensing.

For broader options by condition and supplies, browse Diabetes Care. You can also explore articles and guides to support planning and adherence.

Availability and Substitutions

Inventory may vary by strength, package size, and formulation. If a particular tablet is temporarily unavailable, your prescriber may recommend an equivalent regimen using separate components or a different approved combination. When considering the extended-release form, remember that Jentadueto XR price can differ from immediate-release options because the technology and pack sizes vary. Do not switch between immediate-release and extended-release without your healthcare professional’s guidance.

Patient Suitability and Cost-Saving Tips

This treatment may suit adults who need dual action through complementary mechanisms and prefer either a twice-daily tablet with meals or an extended-release once-daily option. It may not suit those with severe kidney impairment, unstable heart or lung disease, heavy alcohol use, or a history of pancreatitis without careful review. Talk with your clinician about monitoring vitamin B12 if you use metformin long term.

To manage overall spending, consider multi-month refills when appropriate, as fewer refills can reduce per-order fees. Set calendar reminders to request your next fill before running low. Review whether a class alternative or a different strength aligns with your plan and budget. If you are paying cash, you can check Jentadueto cash price against other options listed in our catalog.

Missed Dose and Timing

If you occasionally forget a dose, tie dosing to routine meals or daily tasks. A simple reminder on your phone can help keep your schedule steady. Avoid doubling up after a missed dose. If recurring nausea or stomach upset occurs, ask your clinician about taking doses with your main meal or whether an extended-release option could be appropriate.

Storage and Travel Basics

Keep tablets in a dry, room-temperature setting, away from moisture and heat. Use child-resistant caps and store out of children’s reach. When traveling, keep medicines in your carry-on and bring a copy of your prescription and a medication list. If your trip spans time zones, maintain roughly the same interval between doses. For education and motivation, you may find our features like Reverse Prediabetes Naturally and National Diabetes Month 2025 helpful. For digestion-related questions, see Does Metformin Cause Diarrhea.

Questions to Ask Your Clinician

• Fit with plan: how it complements my current regimen
• Kidney checks: how often to monitor function
• GI comfort: tips to manage stomach symptoms
• Low sugar risk: signs when used with insulin
• Imaging tests: holding metformin for contrast
• B12 levels: whether monitoring is needed

Authoritative Sources

Official Product Site

Boehringer Ingelheim

Health Canada Drug Product Database

Ready to get started? Buy Jentadueto online with US shipping from Canada and enjoy prompt, express shipping with temperature-controlled handling when required. This information is educational and not a substitute for advice from your healthcare professional. Always follow your prescriber’s instructions and the official label.