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Kivexa® Tablets for HIV-1
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What Kivexa Is and How It Works
Kivexa is a fixed-dose tablet for HIV-1 combination therapy. It contains abacavir and lamivudine, and this page helps you compare options and check Kivexa price without insurance. Information on access supports US delivery from Canada.
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
This medicine combines two nucleoside reverse transcriptase inhibitors (NRTIs). It helps lower viral replication when used with other antiretrovirals. The treatment is typically part of a complete regimen selected by your prescriber. When used consistently, it can support viral suppression goals alongside adherence and regular lab monitoring. For broader context on condition care, see our Hiv category.
Who It’s For
This therapy is indicated, in combination with other antiretrovirals, for adults and adolescents who meet weight and clinical criteria per the official label. It is not appropriate for people with known hypersensitivity to abacavir, including those who test positive for HLA‑B*5701. Those with moderate to severe hepatic impairment should avoid it. The fixed-dose tablet is not recommended when dose adjustments are needed for significant renal impairment. If you have chronic hepatitis B, discuss careful management because lamivudine withdrawal can lead to flares. For public health context, you can also review Hiv Testing Day.
Dosage and Usage
Standard labeling supports one tablet taken once daily, used with other antiretrovirals chosen by your clinician. Take it with or without food. Do not restart if you ever had a suspected abacavir hypersensitivity reaction. Screening for HLA‑B*5701 is recommended before first use. Keep a consistent daily schedule and coordinate dosing with other agents in your regimen.
Swallow the tablet whole with water. If your care team adjusts the other components of your regimen, continue this tablet as instructed unless they advise a change. Do not split or crush unless your prescriber confirms it is acceptable. When uncertain about administration questions, defer to the official product information and your healthcare professional’s guidance. For background on regimen-building basics, see this overview on Medication Uses.
Strengths and Forms
The tablet is supplied as a film‑coated dose that combines abacavir 600 mg and lamivudine 300 mg in a single daily tablet. Pack sizes commonly include 30 tablets. Availability can vary by market and manufacturer packaging.
Missed Dose and Timing
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your usual schedule. Do not double up. If vomiting occurs shortly after a dose and you are unsure whether to take another, check the official label or contact your prescriber or pharmacist.
Storage and Travel Basics
Store tablets at room temperature in a dry place, away from excess heat and moisture. Keep them in the original, child‑resistant container with the label intact. Do not use tablets that are damaged, expired, or show unusual appearance. Keep all medicines out of reach of children and pets.
When traveling, carry your medicines in your hand luggage with the original labeled container. Bring a copy of your prescription and a medication list. If crossing borders, allow extra time for security checks and keep documentation accessible. Use a travel pill organizer only if it will not compromise identification of the tablets. If your prescriber changes your regimen, update your travel supply plan accordingly.
Benefits
This NRTI backbone offers once‑daily dosing in a single tablet, which can simplify multi‑drug regimens. It can be taken with or without food, allowing flexible scheduling. The long history of use with other antiretrovirals supports well‑established place‑in‑therapy under label guidance. Tablets are familiar to most people and convenient for storage and travel.
Side Effects and Safety
- Common effects: nausea, headache, fatigue
- Sometimes reported: diarrhea, insomnia, cough
- Skin: rash may occur; stop and seek help if severe
Serious risks can include a hypersensitivity reaction to abacavir, which may be life‑threatening. Stop the medicine and seek urgent care if symptoms such as fever, rash, fatigue, shortness of breath, cough, sore throat, gastrointestinal upset, or general malaise occur together. Do not restart after a suspected hypersensitivity reaction. Lactic acidosis and hepatomegaly with steatosis have been reported with nucleoside analogues. Immune reconstitution syndrome may occur after starting combination therapy. People with chronic hepatitis B can experience disease exacerbations after stopping lamivudine; close monitoring is recommended.
Drug Interactions and Cautions
Do not take this fixed‑dose tablet with other products containing abacavir or lamivudine. Avoid coadministration with dofetilide. Alcohol may increase abacavir exposure; discuss use with your clinician. Sorbitol‑containing solutions can reduce lamivudine levels. Methadone maintenance may require monitoring for withdrawal symptoms. Combining with emtricitabine is generally not recommended due to therapeutic duplication. Always provide a complete medication list, including OTC and herbal products. For a broader overview, see Drug Interactions.
What to Expect Over Time
With consistent dosing and a complete regimen, viral load may decline toward suppression, as assessed by periodic lab tests. CD4 counts may improve over time. You may not feel different day to day, so lab follow‑up remains essential. Adherence tools such as reminders, weekly pill checks, and travel planning can help maintain continuity. Report new symptoms, especially rash or multi‑system reactions, promptly to your prescriber.
Compare With Alternatives
Depending on your regimen goals and prior history, your prescriber may consider other combinations. For a three‑drug single‑tablet option that includes the same NRTI backbone plus an integrase inhibitor, ask about Triumeq®. For a two‑drug single‑tablet option that uses lamivudine with an integrase inhibitor, some adults may be candidates for Dovato®. Your clinician will select therapy based on resistance testing, comorbidities, and treatment goals.
Pricing and Access
We use transparent Canadian pricing to support affordability. If you are comparing options, you can review abacavir lamivudine price on our product pages. You may also Promotions for current offers, when available. For patients coordinating refills, Order abacavir lamivudine online through our secure checkout, and track your order easily. We provide clear invoices to help with reimbursement claims.
For cross‑border fulfillment, this product Ships from Canada to US after prescription verification. Our site uses encrypted checkout to help protect your information. If your prescriber changes your regimen, update your order details before placing a refill to avoid delays.
Availability and Substitutions
Supply can vary by lot and packaging. If the tablet is temporarily unavailable, your prescriber may recommend a therapeutically appropriate alternative. In many cases, abacavir lamivudine from Canada remains accessible through equivalent presentations, subject to prescription review. Do not change therapy without guidance from your healthcare professional.
Patient Suitability and Cost-Saving Tips
Not everyone is a candidate. People with a prior abacavir hypersensitivity reaction or positive HLA‑B*5701 test must not use this medicine. Those with severe liver disease, significant renal impairment requiring lamivudine dose adjustment, or overlapping components in other products should avoid the fixed‑dose tablet. Discuss pregnancy, breastfeeding, and all comorbid conditions with your prescriber.
For budgeting, consider multi‑month quantities when appropriate, as fewer shipments can reduce overall fees. Set refill reminders for at least a week before you will run out. Ask your prescriber whether generic or alternative regimens fit your history and resistance profile. If eligible, you may find a Kivexa discount through periodic site offers; availability varies.
Questions to Ask Your Clinician
- Is HLA‑B*5701 testing on file before I start?
- How does this backbone fit with my other antiretrovirals?
- What labs and follow‑up schedule should I expect?
- What signs of hypersensitivity should prompt urgent care?
- Are any of my current medicines likely to interact?
- If I have hepatitis B, how will stopping lamivudine be managed?
- What adherence strategies should I use when traveling?
Authoritative Sources
Health Canada DPD: KivexaFDA DailyMed: Abacavir/Lamivudine (Epzicom)ViiV Healthcare
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How does Kivexa work with other HIV medicines?
Kivexa contains two nucleoside reverse transcriptase inhibitors, abacavir and lamivudine. These agents help block reverse transcriptase, a viral enzyme HIV uses to replicate. Most people take this tablet as part of a complete regimen that includes medicines from other classes, such as integrase inhibitors or NNRTIs. Your prescriber selects the full combination based on your health history, resistance testing, and treatment goals. Regular labs help confirm effectiveness.
Who should not take Kivexa?
Do not use Kivexa if you had a previous hypersensitivity reaction to abacavir or if you test positive for HLA‑B*5701. Avoid it in severe hepatic impairment and when significant renal impairment requires lamivudine dose changes. Do not combine it with other products that contain abacavir or lamivudine. Always discuss pregnancy, breastfeeding, liver disease, and hepatitis B status with your healthcare professional.
Can I take Kivexa with food or alcohol?
You may take Kivexa with or without food. Alcohol can increase abacavir exposure, so ask your clinician about safe use based on your health and regimen. If you drink, keep intake moderate and consistent, and report any new symptoms. Never use the tablet with dofetilide, and share a full list of medicines, vitamins, and herbal products with your prescriber and pharmacist.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue your regular schedule. Do not take two doses at once. If you vomit soon after dosing or miss multiple doses, consult the official label or your healthcare professional for advice. Maintaining a daily routine and reminders can help prevent missed doses.
Are there serious side effects I should watch for?
Seek urgent care if you develop symptoms suggestive of abacavir hypersensitivity, such as fever, rash, fatigue, shortness of breath, cough, sore throat, or gastrointestinal upset occurring together. Other serious risks include lactic acidosis, hepatomegaly with steatosis, and immune reconstitution syndrome. People with chronic hepatitis B may have flares after stopping lamivudine-containing regimens. Review the product information for full safety details.
How is Kivexa stored at home and during travel?
Store tablets at room temperature in the original container, away from heat and moisture. Keep out of reach of children and pets. When traveling, carry your medicines in hand luggage with the labeled container and a medication list. Bring your prescription for security checks. Use a pill organizer only if it will not cause confusion or remove essential labeling needed for identification.
What interactions are important with Kivexa?
Avoid combining Kivexa with other products that contain abacavir or lamivudine. Do not take it with dofetilide. Alcohol can raise abacavir levels, and sorbitol can reduce lamivudine exposure. Methadone maintenance may require monitoring. Always provide your prescriber with a complete list of medicines, vitamins, and herbal products to help identify potential interactions early.
