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Kivexa is a medication used in combination with other antiretroviral drugs to treat adults infected with HIV-1. It contains two active ingredients, abacavir and lamivudine, which work together to prevent the virus from multiplying and progressing to AIDS.
Benefits
Kivexa helps manage HIV-1 infection by reducing the viral load in the body, improving immune function, and slowing the progression of the disease. This can lead to a better quality of life for those living with HIV.
How to Use
Kivexa is typically taken as one pill daily, in combination with other antiretroviral medications. It can be taken with or without food. It is important to follow your healthcare provider’s instructions regarding dosage and administration.
Possible Side Effects
- Migraine
- Rash
- Nausea
- Fatigue
- Vomiting
- Diarrhea
- Gastritis
- Abnormal dreams
- Vertigo
- Headache
- Fever
- Anxiety
- Depression
- Insomnia
In rare cases, hypersensitive reactions to abacavir, a component of Kivexa, can occur and may be severe. Contact your doctor immediately if you experience any unusual symptoms.
Warnings and Precautions
Kivexa should not be taken by individuals with hepatic impairment or those who have had a hypersensitive reaction to abacavir or any other ingredients in the medication. Patients with the HLA-B*5701 allele are at increased risk for hypersensitivity reactions and should be tested before starting treatment. Discontinue use if symptoms of hepatotoxicity or lactic acidosis occur. Regular monitoring is recommended for patients also taking interferon alfa. Kivexa is not recommended for patients with a creatinine clearance of less than 50 ml/min.
Storage
Store Kivexa at room temperature, away from moisture and heat. Keep it out of reach of children and pets.
Additional Information
Alcohol may affect the elimination of abacavir from the body. Kivexa should not be taken with zalcitabine, as these drugs can inhibit each other’s effectiveness. Pregnant women should only use Kivexa if the benefits outweigh the risks, and breastfeeding is not recommended for HIV-positive mothers due to the risk of transmission.
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