Lantus® Vial for Once-Daily Basal Insulin Therapy

What Lantus® Is and How It Works

Lantus Vial contains insulin glargine U-100, a long-acting basal insulin. It helps control fasting and between-meal blood glucose in adults with type 1 or type 2 diabetes, and in pediatric patients with type 1 diabetes. Many people compare the Lantus Vial price when they buy Lantus Vial or order Lantus Vial online, including those seeking Lantus insulin without insurance.

YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba, and licensed pharmacists review prescriptions before dispensing.

Lantus works by releasing small, steady amounts of insulin over 24 hours. It starts working in about 1–2 hours, has no pronounced peak, and typically lasts up to 24 hours. It is given by subcutaneous injection once daily at the same time each day. Lantus is not for intravenous use, not for insulin pumps, and should not be mixed or diluted with other insulins. The vial is 10 mL at 100 units/mL.

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Dosage and Usage

• Use subcutaneously once daily at the same time. Some patients may require twice-daily dosing as directed by a prescriber.
• The total daily dose and titration are individualized. Small adjustments are often made every few days based on glucose logs under medical guidance.
• Typical injection sites: abdomen, thigh, or upper arm. Rotate sites to reduce lipodystrophy.
• Do not mix or dilute Lantus with other insulins. Do not use in an insulin pump.
• Use only U-100 insulin syringes to draw doses from the vial.
• Check the solution before use. It should be clear and colorless with no particles.
• Missed dose: take as soon as remembered the same day. If near the next scheduled dose, follow prescriber guidance to avoid stacking doses.
• Hypoglycemia risk increases if combined with prandial insulin or a sulfonylurea; dose reductions may be needed per clinician direction.

• Store unopened vials in a refrigerator at 2–8°C (36–46°F). Do not freeze. Keep away from the freezer compartment.
• After first puncture, keep the vial at room temperature (up to 25–30°C/77–86°F) or refrigerated. Discard 28 days after first use.
• Protect from direct heat and light. Do not expose to temperatures above 30°C (86°F).
• For travel, keep vials in an insulated pouch with cold packs. Do not place insulin directly against ice packs.
• Carry a backup supply, syringes, and glucose monitoring supplies. Keep insulin in your hand luggage during flights.
• If exposed to extreme temperatures, replace the vial and consult a pharmacist about safe use.

Benefits and Savings

Lantus provides steady basal coverage for 24 hours with once-daily dosing. It supports predictable fasting glucose and smoother day-to-day control. Many patients find fewer nocturnal lows compared with NPH. The vial format offers dosing flexibility at an affordable Lantus Vial cost, and can be paired with rapid-acting insulin for mealtime needs.

Ordering Lantus Vial online from Canadian pharmacies can deliver 60–80% savings versus typical U.S. prices. Those paying out of pocket or comparing the Lantus Vial cash price may see meaningful Lantus Vial savings, even without insurance. Multi-month supplies and bulk promotions may lower the per-month cost.

For extra value, see our Lantus Vial coupon page for current promotions.

Side Effects and Safety

• Hypoglycemia (shakiness, sweating, confusion, headache)
• Injection site reactions (redness, itching, mild swelling)
• Lipodystrophy or skin thickening at injection sites
• Peripheral edema
• Weight gain
• Nausea
• Rash or pruritus
• Nasopharyngitis or mild upper-respiratory symptoms

Serious risks include severe hypoglycemia, hypokalemia, and rare systemic allergic reactions. Fluid retention may occur with thiazolidinediones. Do not use during episodes of hypoglycemia. Lantus is not for diabetic ketoacidosis; IV insulin is required for DKA. The risk of hypoglycemia increases when combined with prandial insulin or a sulfonylurea; dose adjustments may be needed under medical supervision.

Onset Time

Lantus begins lowering glucose about 1–2 hours after injection. Its effect is stable across 24 hours without a clear peak. Fasting glucose may improve within several days, and dose changes typically show full effect within 3–5 days. A1C reduction is usually assessed over 8–12 weeks as the regimen stabilizes.

Compare With Alternatives

Insulin degludec (Tresiba) is an ultra-long-acting basal insulin lasting beyond 24 hours and is usually taken once daily at flexible times. Some patients prefer its dosing window, while others stay with Lantus for familiar performance and access.

Insulin detemir (Levemir) is a long-acting basal that may require twice-daily dosing in some patients. Lantus is often once daily. Switching between long-acting insulins requires prescriber guidance and careful monitoring.

NPH human insulin is more affordable but has a pronounced peak and higher nocturnal hypoglycemia risk. Lantus offers smoother basal coverage with fewer peaks, which many patients find easier to manage.

If a pen format is preferred, consider Lantus® Cartridges for compatible pen devices. For mealtime control, a rapid insulin such as Fiasp® Vial can be paired with Lantus as part of a basal-bolus regimen when prescribed.

Combination Therapy

• With metformin for type 2 diabetes to improve fasting and overall control.
• With rapid-acting insulin at meals for basal-bolus therapy in type 1 or advanced type 2.
• With a GLP-1 receptor agonist to reduce insulin needs and weight gain.
• With an SGLT2 inhibitor in appropriate patients for additional A1C and cardiovascular or renal benefits.
• With a sulfonylurea, monitor closely; a dose reduction of the sulfonylurea or basal insulin may be required to reduce hypoglycemia risk.

Patient Suitability and Cost-Saving Tips

Lantus is indicated for adults with type 1 or type 2 diabetes and for pediatric patients with type 1 diabetes. It is not for patients with diabetic ketoacidosis. Use caution in renal or hepatic impairment and in those with recurrent hypoglycemia. Training on injection technique, dose titration, and hypoglycemia recognition is essential.

Patients who prefer vial-and-syringe dosing, need flexible small dose changes, or want a lower entry cost may choose the vial format over pens. Those who need pen convenience can consider cartridges or prefilled pens. Discuss pregnancy and breastfeeding considerations with a healthcare professional.

To manage the Lantus Vial cost, consider a multi-month supply to reduce shipping frequency, and watch for a Lantus Vial discount during site promotions. Reorder reminders can help prevent gaps in therapy. Some patients compare the Lantus Vial out of pocket expense to biosimilar insulin glargine products when appropriate. A Lantus Vial bulk buy can decrease the per-month price for ongoing therapy. These approaches can help patients paying for Lantus insulin without insurance.

Authoritative Sources

Sanofi Lantus product information

Health Canada Drug Product Database: Lantus entry

FDA Prescribing Information for Lantus (insulin glargine)

Order Lantus® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This content is educational and does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider about your health and medicines.