Lisdexamfetamine for ADHD and Binge-Eating Disorder – Vyvanse® Equivalent

What Lisdexamfetamine Is and How It Works

Lisdexamfetamine is a central nervous system stimulant used for attention-deficit/hyperactivity disorder (ADHD) in patients 6 years and older and for moderate to severe binge-eating disorder (BED) in adults. It contains lisdexamfetamine dimesylate, a prodrug converted to dextroamphetamine after absorption. This conversion supports steady lisdexamfetamine effects during the day. Many people look for lisdexamfetamine without insurance, and Canadian pricing can help reduce costs.

YouDrugstore is a licensed Canadian pharmacy in Manitoba, and every prescription is reviewed by a licensed pharmacist before dispensing.

We also work with vetted international partner pharmacies when needed, offering authentic brand medications, broad availability, and affordable pricing.

Formulations include oral capsules and chewable tablets taken once daily in the morning. The lisdexamfetamine drug class is amphetamine stimulants. In ADHD, lisdexamfetamine uses include improving attention and reducing impulsivity and hyperactivity. In BED, it helps reduce the number of binge-eating days. Lisdexamfetamine Vyvanse comparisons are direct, as Vyvanse is the original brand of lisdexamfetamine dimesylate.

Dosage and Usage

• Typical starting dose: 30 mg once daily in the morning. Increase by 10–20 mg at weekly intervals to the lowest effective dose.
• Usual effective dose range: 30–70 mg once daily. Maximum recommended daily dose: 70 mg.
• For binge-eating disorder: start 30 mg daily; titrate to 50–70 mg daily based on response and tolerability.
• Available strengths often include lisdexamfetamine 30mg, lisdexamfetamine 40mg, and lisdexamfetamine 50mg, among others up to 70 mg.
• Capsules: swallow whole, or open and mix the entire contents with yogurt, water, or orange juice. Consume right away without storing the mixture. Do not divide the dose.
• Chewable tablets: chew completely before swallowing. Do not swallow chewables whole.
• Take with or without food. Avoid afternoon or evening dosing because of insomnia risk.
• Missed dose: take in the morning when remembered. If it is later in the day, skip the missed dose and resume the next morning. Do not double the dose.
• Avoid taking with strong acidifying agents (may lower exposure) or alkalinizing agents (may increase exposure) unless advised by your prescriber.
• Lisdexamfetamine is a controlled prescription medicine. Store securely and never share.

• Store at 20–25 °C (68–77 °F); short excursions 15–30 °C (59–86 °F). Keep dry and protect from light.
• Keep in the original, child-resistant container. Do not repackage into pill bags for travel.
• For travel, carry your labeled container and prescription in your carry-on. Check local regulations for controlled medicines.
• Do not leave medicine in a hot car or in freezing conditions.
• If mixing capsule contents with food or liquid, take immediately and discard any unused portion.
• Set reminders for morning dosing to support a steady routine.

Benefits and Savings

Lisdexamfetamine provides once-daily dosing that covers school or work hours. In ADHD, patients often report better attention and task follow-through. In BED, many see fewer binge episodes per week. Chewable and capsule options offer flexibility. While some notice weight change, lisdexamfetamine weight loss is not an approved use and should not be the treatment goal.

You can expect significant savings at Canadian prices. Many orders see 60–80% lower costs versus typical US prices. Choosing lisdexamfetamine generic often reduces the lisdexamfetamine price further. We also carry brand alternatives when preferred. Ask about lisdexamfetamine dimesylate cost differences across strengths. Savings can help those comparing lisdexamfetamine cost without insurance.

For limited-time offers, see our lisdexamfetamine coupon page.

Multi-month supplies may lower the effective per-month cost, and we can send gentle reorder reminders before you run low.

Side Effects and Safety

• Common lisdexamfetamine side effects: decreased appetite, dry mouth, insomnia, headache, irritability, and anxiety.
• Other effects: nausea, stomach pain, dizziness, weight loss, increased heart rate, and blood pressure.
• Chewables may have a taste change or mouth discomfort in some users.
• In children, monitor appetite, weight, and growth over time.
• Rare effects: skin color changes in fingers or toes (Raynaud’s phenomenon) or circulation issues.
• Sexual side effects and sweating can occur.
• Lisdexamfetamine dimesylate side effects can interact with other medicines, including serotonergic drugs.

Serious risks include abuse and dependence, cardiac events, new or worsening psychosis or mania, priapism, seizures, and serotonin syndrome when combined with certain antidepressants. Do not use with monoamine oxidase inhibitors (MAOIs) or within 14 days of MAOI therapy. Stimulants may be contraindicated with certain heart conditions, hyperthyroidism, glaucoma, or severe agitation. Report chest pain, fainting, shortness of breath, hallucinations, or severe mood changes promptly.

Onset Time

Many feel initial ADHD symptom control within a few hours of the first dose. Consistent daytime coverage is expected after the first week at a stable dose. Full benefit often emerges after titration over 2–4 weeks. In BED, reductions in binge days often appear within 1–2 weeks, with continued improvement through 12 weeks as the dose is optimized.

Response varies by individual. Some adjust sooner, while others may need additional dose changes. If sleep disturbance occurs, earlier morning dosing and good sleep hygiene can help. For broader sleep tips, see our article How To Treat The Most Common Sleep Disorders.

Compare With Alternatives

Other stimulants include methylphenidate-based medicines (such as long-acting formulations) and mixed amphetamine salts. These differ in duration, titration steps, and side-effect profiles. Some people respond better to one stimulant class than another.

Non-stimulant options include atomoxetine and alpha-2 agonists like guanfacine extended-release. These can help when stimulants are not suitable. Bupropion is another option used off-label in some adults; see Wellbutrin® Xl for details.

For condition-specific guidance, explore Attention Deficit Hyperactivity Disorder Adhd and Binge Eating Disorder.

Combination Therapy

• Behavioral therapy and skills training alongside medication for ADHD.
• Cognitive behavioral therapy for binge-eating disorder to reduce triggers and relapse.
• Adjunct non-stimulants (e.g., guanfacine ER) in select cases under prescriber oversight.
• Antidepressants may be combined cautiously; monitor for serotonin syndrome and blood pressure changes.
• Avoid MAOIs and avoid combining with other stimulants.
• Manage dosing time and sleep hygiene to reduce insomnia risks.

Patient Suitability and Cost-Saving Tips

Lisdexamfetamine may suit patients who need once-daily control for ADHD or BED. Those with significant anxiety, uncontrolled hypertension, symptomatic cardiovascular disease, glaucoma, hyperthyroidism, or a history of certain psychiatric conditions may require alternatives. A thorough assessment is important in patients with substance use history, as stimulants carry dependence risks.

Pregnant or breastfeeding patients should discuss benefits and risks with their clinician. Children and adolescents should have growth and appetite monitored regularly. Any new chest pain, palpitations, fainting, or marked mood changes needs prompt evaluation. Keep this controlled medicine secure at home.

To reduce the lisdexamfetamine cost, consider the lisdexamfetamine generic, compare lisdexamfetamine price across strengths, and ask about multi-month fills when appropriate. Bulk promotions may lower per-month costs. Reorder reminders can help you stay on schedule. These steps may be especially helpful for lisdexamfetamine cost without insurance. We carry lisdexamfetamine for sale at Canadian pricing for US customers with valid prescriptions.

Authoritative Sources

FDA Prescribing Information for Vyvanse (lisdexamfetamine)

FDA Medication Guide: Vyvanse

Health Canada Drug Product Database: Lisdexamfetamine

Order Lisdexamfetamine from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This information is educational and does not replace medical advice from your healthcare professional. Always follow your prescriber’s directions and the supplied patient information.