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Mekinist

Cancer

Please note: a valid prescription is required for all prescription medication.

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$12,599.99

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Mekinist is a kinase inhibitor approved to treat certain cancers with BRAF V600 mutations. It can be used alone to treat people with inoperable or metastatic melanoma. It is approved in combination with the companion drug Tafinlar for treatment of inoperable or metastatic melanoma and for prevention of melanoma recurrence after surgery. The combination is also approved for metastatic non-small-cell lung cancer (NSCLC) and advanced thyroid cancer.

Benefits

Helps slow or stop the growth of cancers with BRAF mutations.
Often used with other medications like dabrafenib for better results.
Can reduce the size of tumors and help relieve symptoms.
Taken orally, so it’s easy to use at home.

Dosage

The usual dose is 2 mg once daily.
Should be taken at the same time each day.
Must be taken on an empty stomach, either 1 hour before or 2 hours after food.
Tablets should be swallowed whole with water — do not crush or chew.

Warnings and Precautions

Only for cancers with a confirmed BRAF V600 mutation.
May cause heart problems, including changes in heart function — regular check-ups are needed.
Can affect lungs, eyes, and skin — report any new symptoms right away.
Not safe during pregnancy or breastfeeding — use effective birth control.
Can interact with other medications — always tell your doctor what you’re taking.

Usage Instructions

Take once a day at the same time.
Always take on an empty stomach.
If you miss a dose and it’s less than 12 hours late, take it. If more than 12 hours, skip it and take the next dose as scheduled.
Do not take two doses at once.
Continue taking as prescribed, even if you feel better.

Storage Information

Store in a refrigerator between 2°C and 8°C.
Keep the tablets in the original bottle with the cap tightly closed.
Protect from moisture and light.
Keep out of reach of children.

Common Side Effects

Mild to moderate effects: rash, diarrhea, tiredness, swelling, nausea, fever, or dry skin.
Serious (seek medical attention): shortness of breath, vision changes, signs of heart problems (such as dizziness or swelling), bleeding, or severe skin reactions.

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