Myleran® Tablets for Chronic Myeloid Leukemia

Myleran® is a prescription cancer medicine used for chronic myeloid leukemia. It helps slow abnormal white blood cell growth. With US delivery from Canada, this page explains access, dosing basics, and what to expect, including typical costs without insurance.

What Myleran Is and How It Works

Myleran® contains busulfan, an alkylating agent. It works by forming crosslinks in DNA, which can slow or stop rapidly dividing blood cancer cells. Clinicians have used this medicine in certain chronic myeloproliferative disorders, most notably chronic myeloid leukemia, under specialist supervision. YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

This treatment is taken by mouth. Your prescriber individualizes the plan based on blood counts, response, and tolerability. Regular lab monitoring guides adjustments. Always follow the instructions on your prescription label and the medication guide supplied with your order.

Who It’s For

This therapy is used in adults diagnosed with Chronic Myeloid Leukemia. It may be considered when targeted therapies are not appropriate, not tolerated, or have lost effectiveness. Some clinicians may use it in other myeloproliferative conditions per approved labeling and local guidelines. Busulfan 2 mg tablets can lower elevated white blood cell counts when managed by an experienced oncology team.

People who are pregnant should not take this medicine. Those planning to conceive should discuss fertility risks and birth control before starting treatment. Avoid use if you have a known allergy to busulfan. Your healthcare professional will weigh benefits and risks if you have significant liver or lung disease, prior intensive chemotherapy, or a history of seizures.

Dosage and Usage

Your dosing schedule is individualized. Many regimens use once-daily dosing, with adjustments based on frequent blood count monitoring. Swallow tablets whole with water. You may take it with or without food, but try to be consistent in your routine to support predictable absorption.

Do not crush, split, or chew the tablets. If you experience nausea, speak with your prescriber about supportive care options. Keep all lab appointments and report signs of low blood cells such as unusual bruising, mouth sores, fever, or infections. If your clinic changes the dose or schedule, use a new pill calendar to avoid errors. When in doubt, refer to the official label or contact your oncology team.

Strengths and Forms

This medication is available as oral tablets. Availability may vary by supplier and market.

• Myleran 2 mg tablets

Some regions may have a generic version with the same active ingredient. Your pharmacist will dispense the brand or an equivalent product based on your prescription and local availability.

Missed Dose and Timing

If you miss a dose, take it as soon as you remember unless it is close to your next scheduled dose. If it is near the time of the next dose, skip the missed dose and resume your regular schedule. Do not take two doses at once. If multiple doses are missed, contact your prescriber for guidance. Keep a written log or set phone reminders to help maintain consistency.

Storage and Travel Basics

Store tablets at room temperature in a dry place, away from excessive heat and humidity. Keep them in the original child-resistant container, tightly closed, and out of reach of children and pets. Do not store in the bathroom. For travel, pack your medicine in your carry-on with a copy of your prescription. Use a daily pill organizer if approved by your prescriber, and carry contact information for your clinic in case plans change while you are away.

Benefits

This treatment offers an oral option for certain patients with chronic myeloid leukemia. It can reduce elevated white blood cell counts under careful monitoring. Taking tablets at home may be more convenient than frequent clinic visits for infusions. Your prescriber may pair it with supportive care to manage blood counts and symptoms over time.

Side Effects and Safety

• Lowered blood counts
• Tiredness
• Nausea or vomiting
• Loss of appetite
• Diarrhea or constipation
• Headache
• Skin darkening

Serious risks can include severe myelosuppression, infections, lung problems, liver injury, seizures (more often with high-dose regimens), infertility, and secondary cancers. Contact a clinician urgently for fever, shortness of breath, persistent cough, yellowing skin or eyes, severe abdominal pain, unusual bleeding, or seizures. Your oncology team will monitor labs and adjust treatment as needed to reduce risks.

Drug Interactions and Cautions

Tell your prescriber about all medicines, vitamins, and herbal products. Some antimicrobials, such as metronidazole or certain azoles, may raise busulfan exposure. Acetaminophen can affect glutathione pathways and may alter busulfan levels if used frequently. Enzyme-inducing anticonvulsants can change drug handling. Combining with other bone marrow–suppressing treatments can increase low blood counts. Avoid live vaccines during therapy. Alcohol can worsen liver strain; ask your prescriber for specific advice.

What to Expect Over Time

Your team will check complete blood counts regularly at the start and then at intervals. White blood cell levels may decline gradually as treatment continues. Plans can change based on response, tolerability, and goals of care. Keep a journal of side effects and questions between visits. Good adherence, safe handling, and prompt reporting of symptoms help your clinician steer dosing and supportive measures.

To learn more about the condition and care journey, see our resources on What Is Leukemia and Symptoms Causes And Treatment. For broader oncology options, browse our Cancer category.

Compare With Alternatives

Targeted therapies are often first-line for chronic myeloid leukemia. Two options we carry include:

• Gleevec® (imatinib), a tyrosine kinase inhibitor for Ph+ CML
• Sprycel® (dasatinib), another TKI used across multiple CML phases

These medicines work differently from alkylating agents. Your prescriber will select therapy based on disease phase, prior response, comorbidities, and treatment goals. For condition background, visit Chronic Myeloid Leukemia and review options in our Cancer Drugs List.

Pricing and Access

We offer Canadian pharmacy value with transparent information to help you plan care. Busulfan cost varies by supplier, quantity, and fulfillment. You can view current pricing on the product page and compare options. We support US delivery from Canada so you can arrange refills through one secure checkout.

Looking to save? Ask your prescriber if a generic is appropriate and consider longer fills when stable. Our team can help you review documentation requirements and verify details with your clinic when needed.

Availability and Substitutions

Stock can change over time. If a particular brand is unavailable, a prescriber may allow an equivalent busulfan product. Generic busulfan tablets may be appropriate when permitted. Prescription required and verified. If substitution is not suitable, your clinician can recommend a different therapy and monitoring plan.

Patient Suitability and Cost-Saving Tips

This medicine may suit adults under oncology care who need an oral cytotoxic option and can complete frequent lab checks. It may not be appropriate for those who are pregnant, planning pregnancy soon, or with uncontrolled liver or lung disease. Discuss fertility preservation before starting if relevant.

To manage therapy and expenses, consider these steps:

• Multi-month fills: Fewer co-pays and fewer shipments when stable
• Generic first: Ask if a non-brand option is allowed
• Clinic alignment: Synchronize lab visits and refill timing
• Clear calendar: Use reminders for dosing and lab days
• Single pharmacy: Keep one profile for safer oversight

Talk with your prescriber and our pharmacists about Busulfan out of pocket cost, documentation, and timing so you can plan ahead without surprises.

Questions to Ask Your Clinician

• What goals are we targeting with this therapy?
• How often will my blood counts be checked at the start?
• Which symptoms should trigger a call or urgent visit?
• Are there medicines or supplements I should avoid?
• How long might I stay on treatment if tolerated?
• What fertility or pregnancy precautions are needed?
• Could a generic be appropriate for me?

Authoritative Sources

• FDA DailyMed
• Health Canada DPD
• US Prescribing Information

Order Myleran tablets with prompt US delivery from Canada. This information is not a substitute for professional medical advice; always follow your prescriber’s directions and the official label.