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Naltrexone HCL 

Naltrexone HCL Tablets for Alcohol Use Disorder

Alcohol Use Disorder, Opioid Use Disorder

Please note: a valid prescription is required for all prescription medication.

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Naltrexone HCL is a prescription tablet for alcohol or opioid dependence. YouDrugstore offers US delivery from Canada so you can access licensed pharmacy care. Many people compare options when paying without insurance, and this page explains the basics clearly.

What Naltrexone HCL Is and How It Works

YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing. ReVia® is a branded form of this opioid receptor antagonist. It blocks mu-opioid receptors and reduces the rewarding effects of opioids and alcohol. With counseling, naltrexone hcl 50mg tablets can help reduce cravings and support abstinence. The medicine is not an opioid and is not habit-forming. This treatment does not treat withdrawal and must not be started while opioids are still in the body.

For alcohol use disorder, the drug can reduce heavy drinking days when used with support. For opioid use disorder, it helps maintain abstinence in patients who are already opioid-free. It can increase sensitivity to opioids after stopping, so accidental exposure later may carry higher risk.

Who It’s For

Naltrexone hydrochloride 50 mg tablets are indicated as part of a complete program including psychosocial support. It is for adults who have stopped alcohol or opioids and want to prevent relapse. People currently using opioids, or those in acute opioid withdrawal, must not start this medicine. Those with acute hepatitis or liver failure should not use it. Tell a healthcare professional if you have liver disease, are pregnant or breastfeeding, or need planned surgery with opioid pain control. Learn more about conditions on our Alcohol Use Disorder and Opioid Use Disorder pages.

Dosage and Usage

The usual starting approach uses an assessment to confirm absence of opioids. Some prescribers may begin with a small test dose before the typical daily schedule. A common regimen for the naltrexone 50 mg oral tablet is once daily with water, with or without food. Take it at the same time each day to create a routine. Do not crush or split unless your prescriber directs you. If there is any chance of recent opioid use, clinicians may delay initiation and repeat checks. Always follow the official label and your prescriber’s guidance.

For alcohol dependence, the drug is begun once the patient has stopped drinking. For opioid dependence, a sufficient opioid-free interval is needed before starting therapy. Keep naloxone available if you have loved ones at risk; education and safety planning matter. Read more topic overviews in our Mental Health category.

Strengths and Forms

This medicine is supplied as film-coated tablets. The most common strength is the naltrexone HCl 50 mg tab. Packaging and brands may vary by manufacturer and market availability.

Missed Dose and Timing

If you miss a dose of naltrexone 50 mg pills, take it when remembered the same day. If it is close to the next dose, skip the missed dose. Do not double up. Aim for consistent daily timing to support adherence. If repeated doses are missed, contact your prescriber for advice rather than restarting on your own.

Storage and Travel Basics

Store the tablets at room temperature in a dry place, away from light. Keep them in the original container with the label attached. Use child-resistant closures and store out of reach of children and pets. When traveling, carry your prescription and medicine in your hand luggage. A copy of your prescription or a pharmacy receipt can help with security checks. Do not store in a car glovebox or hot environments for extended periods.

Benefits

As an opioid antagonist, this therapy can reduce the rewarding effects of alcohol and opioids. It may help decrease cravings and support abstinence goals within a structured program. It is non-addictive and does not produce euphoria. Tablets are straightforward to take and can fit into routine counseling schedules. Many patients appreciate having a daily, oral option as part of comprehensive care.

Side Effects and Safety

  • Nausea or stomach discomfort
  • Headache or dizziness
  • Tiredness or trouble sleeping
  • Anxiety or nervousness
  • Joint or muscle pain
  • Loss of appetite

Serious risks can include liver-related problems, allergic reactions, and increased opioid sensitivity after treatment stops. Seek urgent care if you develop signs of liver injury, severe abdominal pain, yellowing skin or eyes, or swelling of the face or throat. If you need emergency pain control, inform medical staff that you take an opioid antagonist. Carry a medical alert card or bracelet if advised.

Drug Interactions and Cautions

Avoid all opioid-containing products, including certain cough syrups, antidiarrheals, and pain medicines. Using opioids while on this treatment can trigger withdrawal, reduce effectiveness, or lead to overdose after the drug is stopped. Tell your clinician about all medicines, vitamins, and supplements. Liver enzyme–affecting drugs may need review. This therapy is not used with methadone or buprenorphine maintenance. Alcohol use can increase certain side effects; your prescriber may recommend abstinence plans and monitoring.

What to Expect Over Time

With consistent dosing and counseling support, cravings may lessen and daily structure can improve. Some side effects appear early and may settle with ongoing use. Regular follow-up helps check liver health and overall progress. Keep therapy appointments, and use reminders to stay on track. If treatment goals change, collaborate with your prescriber before making any adjustments.

Compare With Alternatives

For alcohol dependence support, Campral (acamprosate) is another non-addictive option used with counseling. For opioid dependence, Suboxone (buprenorphine/naloxone) is a partial-agonist therapy used in medication-assisted treatment programs. The right choice depends on history, goals, and medical considerations.

Pricing and Access

See our current naltrexone 50 mg tablet price and compare options by manufacturer. Canadian pharmacy pricing can help patients manage therapy costs, with US delivery from Canada for eligible orders. Checkout is encrypted, and our team can clarify dispensing details. If you are looking for seasonal offers, visit our Promotions page. For education around related conditions and treatments, explore articles like Abilify And Alcohol, Trifluoperazine Uses, and Nucynta Uses Benefits.

Availability and Substitutions

Supply varies by manufacturer. If a specific brand is unavailable, your prescriber may allow a therapeutically equivalent generic. In some cases, a clinician may recommend an alternative therapy, such as acamprosate for alcohol dependence or a different approach for opioid-use recovery. We cannot promise restock dates but will show current options on the product page.

Patient Suitability and Cost-Saving Tips

This therapy suits adults who are abstinent from opioids and seeking support for alcohol or opioid dependence alongside counseling. It is not for people who need ongoing opioid pain medicine or who have active opioid use. Those with significant liver disease need careful evaluation. Ask about multi-month fills where appropriate. Setting refill reminders can help prevent gaps. Discuss generic options and manufacturer sources with your prescriber to balance continuity and costs.

Questions to Ask Your Clinician

  • Is this antagonist appropriate for my treatment goals?
  • How long should I stay on therapy if I respond well?
  • What liver tests and follow-up schedule do you recommend?
  • How should I prepare if I may need surgery or pain control?
  • What signs mean I should contact you promptly?
  • How will this interact with my other medicines or supplements?
  • What counseling or support programs should I add?

Authoritative Sources

DailyMed Naltrexone TabletsHealth Canada DPD: NaltrexoneFDA Prescribing Information

Ready to start? You can order naltrexone 50 mg tablets from YouDrugstore with prompt, express shipping to your address, with temperature-controlled handling when required. This information is educational and not a substitute for professional medical advice.

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