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Naltrexone HCL Tablets for Alcohol Use Disorder
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Naltrexone HCL is a prescription tablet for alcohol or opioid dependence. YouDrugstore offers US delivery from Canada so you can access licensed pharmacy care. Many people compare options when paying without insurance, and this page explains the basics clearly.
What Naltrexone HCL Is and How It Works
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing. ReVia® is a branded form of this opioid receptor antagonist. It blocks mu-opioid receptors and reduces the rewarding effects of opioids and alcohol. With counseling, naltrexone hcl 50mg tablets can help reduce cravings and support abstinence. The medicine is not an opioid and is not habit-forming. This treatment does not treat withdrawal and must not be started while opioids are still in the body.
For alcohol use disorder, the drug can reduce heavy drinking days when used with support. For opioid use disorder, it helps maintain abstinence in patients who are already opioid-free. It can increase sensitivity to opioids after stopping, so accidental exposure later may carry higher risk.
Who It’s For
Naltrexone hydrochloride 50 mg tablets are indicated as part of a complete program including psychosocial support. It is for adults who have stopped alcohol or opioids and want to prevent relapse. People currently using opioids, or those in acute opioid withdrawal, must not start this medicine. Those with acute hepatitis or liver failure should not use it. Tell a healthcare professional if you have liver disease, are pregnant or breastfeeding, or need planned surgery with opioid pain control. Learn more about conditions on our Alcohol Use Disorder and Opioid Use Disorder pages.
Dosage and Usage
The usual starting approach uses an assessment to confirm absence of opioids. Some prescribers may begin with a small test dose before the typical daily schedule. A common regimen for the naltrexone 50 mg oral tablet is once daily with water, with or without food. Take it at the same time each day to create a routine. Do not crush or split unless your prescriber directs you. If there is any chance of recent opioid use, clinicians may delay initiation and repeat checks. Always follow the official label and your prescriber’s guidance.
For alcohol dependence, the drug is begun once the patient has stopped drinking. For opioid dependence, a sufficient opioid-free interval is needed before starting therapy. Keep naloxone available if you have loved ones at risk; education and safety planning matter. Read more topic overviews in our Mental Health category.
Strengths and Forms
This medicine is supplied as film-coated tablets. The most common strength is the naltrexone HCl 50 mg tab. Packaging and brands may vary by manufacturer and market availability.
Missed Dose and Timing
If you miss a dose of naltrexone 50 mg pills, take it when remembered the same day. If it is close to the next dose, skip the missed dose. Do not double up. Aim for consistent daily timing to support adherence. If repeated doses are missed, contact your prescriber for advice rather than restarting on your own.
Storage and Travel Basics
Store the tablets at room temperature in a dry place, away from light. Keep them in the original container with the label attached. Use child-resistant closures and store out of reach of children and pets. When traveling, carry your prescription and medicine in your hand luggage. A copy of your prescription or a pharmacy receipt can help with security checks. Do not store in a car glovebox or hot environments for extended periods.
Benefits
As an opioid antagonist, this therapy can reduce the rewarding effects of alcohol and opioids. It may help decrease cravings and support abstinence goals within a structured program. It is non-addictive and does not produce euphoria. Tablets are straightforward to take and can fit into routine counseling schedules. Many patients appreciate having a daily, oral option as part of comprehensive care.
Side Effects and Safety
- Nausea or stomach discomfort
- Headache or dizziness
- Tiredness or trouble sleeping
- Anxiety or nervousness
- Joint or muscle pain
- Loss of appetite
Serious risks can include liver-related problems, allergic reactions, and increased opioid sensitivity after treatment stops. Seek urgent care if you develop signs of liver injury, severe abdominal pain, yellowing skin or eyes, or swelling of the face or throat. If you need emergency pain control, inform medical staff that you take an opioid antagonist. Carry a medical alert card or bracelet if advised.
Drug Interactions and Cautions
Avoid all opioid-containing products, including certain cough syrups, antidiarrheals, and pain medicines. Using opioids while on this treatment can trigger withdrawal, reduce effectiveness, or lead to overdose after the drug is stopped. Tell your clinician about all medicines, vitamins, and supplements. Liver enzyme–affecting drugs may need review. This therapy is not used with methadone or buprenorphine maintenance. Alcohol use can increase certain side effects; your prescriber may recommend abstinence plans and monitoring.
What to Expect Over Time
With consistent dosing and counseling support, cravings may lessen and daily structure can improve. Some side effects appear early and may settle with ongoing use. Regular follow-up helps check liver health and overall progress. Keep therapy appointments, and use reminders to stay on track. If treatment goals change, collaborate with your prescriber before making any adjustments.
Compare With Alternatives
For alcohol dependence support, Campral (acamprosate) is another non-addictive option used with counseling. For opioid dependence, Suboxone (buprenorphine/naloxone) is a partial-agonist therapy used in medication-assisted treatment programs. The right choice depends on history, goals, and medical considerations.
Pricing and Access
See our current naltrexone 50 mg tablet price and compare options by manufacturer. Canadian pharmacy pricing can help patients manage therapy costs, with US delivery from Canada for eligible orders. Checkout is encrypted, and our team can clarify dispensing details. If you are looking for seasonal offers, visit our Promotions page. For education around related conditions and treatments, explore articles like Abilify And Alcohol, Trifluoperazine Uses, and Nucynta Uses Benefits.
Availability and Substitutions
Supply varies by manufacturer. If a specific brand is unavailable, your prescriber may allow a therapeutically equivalent generic. In some cases, a clinician may recommend an alternative therapy, such as acamprosate for alcohol dependence or a different approach for opioid-use recovery. We cannot promise restock dates but will show current options on the product page.
Patient Suitability and Cost-Saving Tips
This therapy suits adults who are abstinent from opioids and seeking support for alcohol or opioid dependence alongside counseling. It is not for people who need ongoing opioid pain medicine or who have active opioid use. Those with significant liver disease need careful evaluation. Ask about multi-month fills where appropriate. Setting refill reminders can help prevent gaps. Discuss generic options and manufacturer sources with your prescriber to balance continuity and costs.
Questions to Ask Your Clinician
- Is this antagonist appropriate for my treatment goals?
- How long should I stay on therapy if I respond well?
- What liver tests and follow-up schedule do you recommend?
- How should I prepare if I may need surgery or pain control?
- What signs mean I should contact you promptly?
- How will this interact with my other medicines or supplements?
- What counseling or support programs should I add?
Authoritative Sources
DailyMed Naltrexone TabletsHealth Canada DPD: NaltrexoneFDA Prescribing Information
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How does naltrexone help with alcohol use disorder?
Naltrexone blocks mu-opioid receptors in the brain. By dampening the reward pathway, alcohol can feel less reinforcing. Reduced reinforcement may help curb cravings and heavy drinking days. It works best with counseling and support. It is not a cure and does not treat withdrawal. Your clinician will decide when to start and how long to continue based on your response and safety checks.
Can I take naltrexone if I might need opioid pain medicine?
Tell your prescriber if you expect to need opioid pain control for surgery or injury. Naltrexone can block opioid effects and complicate pain management. Your care team may adjust timing or consider alternatives. Never attempt to override blockade with higher opioid doses, which can be dangerous. Carry documentation so emergency teams know you use an opioid antagonist.
What liver precautions are important with this medicine?
This therapy can affect the liver. Clinicians often check baseline liver function and monitor during treatment, especially if you have a history of liver disease or heavy alcohol use. Report symptoms such as yellowing skin or eyes, dark urine, severe stomach pain, or unusual fatigue. Do not drink alcohol if your clinician advises against it. Follow the label and your prescriber’s instructions.
Is naltrexone addictive or a controlled substance?
Naltrexone is not addictive and is not a controlled substance. It does not produce euphoria or sedation at therapeutic doses. It is used to support recovery goals when combined with counseling and structured care. Store the tablets safely and keep them out of reach of children. Only use it under a licensed prescriber’s supervision.
How long do people usually stay on treatment?
Duration varies. Some people take it for several months, while others continue longer based on risk factors and response. Clinicians reassess benefits and safety at intervals. Do not stop suddenly without discussing next steps, especially if there is an ongoing risk of relapse. Follow-up visits help adjust plans and support progress.
What should I do if I miss a dose?
If you miss a dose, take it when you remember on the same day. If it is close to the next dose, skip the missed one and return to your routine. Do not take two doses at once. If you miss several doses, contact your prescriber for guidance before restarting. Keeping a daily reminder can improve adherence.
Can I drink alcohol while taking naltrexone?
Your prescriber may recommend abstinence plans, as the medicine works best with counseling and a commitment to recovery. While it reduces the rewarding effects of alcohol, it does not prevent impairment or other harms. Drinking can increase certain side effects. Always follow medical guidance and the official label for safe use.
