Nardil® Tablets for Depression

Nardil® is a prescription antidepressant for adults with major depressive disorder. This page explains how it works, key safety points, and practical access steps with US delivery from Canada. It also helps you compare options if you pay without insurance.

What Nardil Is and How It Works

This medicine contains phenelzine, a monoamine oxidase inhibitor. It blocks MAO enzymes that break down serotonin, norepinephrine, and dopamine. By limiting this breakdown, brain levels of these chemicals may rise, which can support mood.

YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

Phenelzine is an irreversible MAOI, so enzyme activity recovers gradually after stopping. Diet and drug interaction guidance are essential to reduce risks.

Who It’s For

This treatment is indicated for major depressive disorder, including patients who have not responded to other therapies or who may benefit from an MAOI. It is not usually first line. People with liver disease, a history of pheochromocytoma, or uncontrolled hypertension should avoid it. Safety in children has not been established; older adults may require closer monitoring.

Those who can follow tyramine food restrictions and interaction precautions may be better candidates. If you have bipolar disorder, tell your prescriber, as antidepressants can sometimes precipitate mania.

Explore related conditions in our Antidepressants and Depression pages for broader context.

Dosage and Usage

Follow your prescription label. Typical adult initiation is multiple daily doses, with gradual increases guided by your prescriber. After adequate response, a lower maintenance schedule may be considered. Take tablets at the same times each day. Swallow with water. Food may be taken if it reduces stomach upset.

Do not start, stop, or change any medicine without clinical guidance. This therapy requires careful coordination with all other drugs and supplements you use.

Strengths and Forms

Tablets are the common form. Many references list Phenelzine 15 mg tablets. Generic presentations may be available; availability can vary by manufacturer and jurisdiction.

Missed Dose and Timing

If you miss a dose, take it when remembered that same day. If it is near the next dose, skip the missed dose and resume your regular schedule. Do not double up. Keeping a medication reminder can help maintain consistency.

Storage and Travel Basics

Store tablets at room temperature in the original container with the lid tightly closed. Keep them dry and away from direct light. Always secure medicines out of reach of children and pets. For travel, carry your prescription details, keep tablets in your hand luggage, and plan for time zone changes to maintain spacing between doses. If questioned during screening, present the pharmacy label.

Benefits

This therapy offers an alternative pathway for depressive symptoms when other classes are unsuitable or have not helped. The mechanism targets multiple neurotransmitters, which may support mood and energy. Once stabilized, a simplified schedule may be possible under medical supervision.

Side Effects and Safety

• Common effects: dizziness, drowsiness, dry mouth
• Sleep changes: insomnia or vivid dreams
• Gastrointestinal: constipation, nausea
• Circulatory: orthostatic lightheadedness
• Weight or appetite changes
• Sexual side effects

Serious risks can include hypertensive crisis with high-tyramine foods, serotonin syndrome with interacting drugs, and rare liver problems. Seek urgent care for severe headache, chest pain, palpitations, stiff neck, confusion, high fever, or yellowing of the skin or eyes. Monitor for mood changes, especially early in treatment or around dose changes.

Drug Interactions and Cautions

Do not combine with other MAO inhibitors. Avoid use with most antidepressants, including SSRIs, SNRIs, tricyclics, mirtazapine, bupropion, and trazodone. Many opioids and pain medicines interact, especially meperidine, tramadol, and methadone. Cough and cold products with dextromethorphan or pseudoephedrine can be dangerous. Other interacting agents include linezolid, methylene blue, triptans, buspirone, stimulants, and St. John’s wort.

Washout periods are critical. Many drugs require at least 14 days before starting or after stopping phenelzine; fluoxetine often needs longer. Discuss all prescriptions, OTC products, and supplements with your healthcare professional before any change.

What to Expect Over Time

Early effects may include dizziness or sleep changes, which often lessen. Mood benefits can take time to build. Keep consistent dosing and follow your diet guidance to avoid high-tyramine foods and beverages. Do not stop abruptly without advice, as symptoms may return and interactions can persist while the enzyme recovers.

For seasonal patterns or motivation support, you may find background education helpful, such as our article on Seasonal Affective Disorder, or mental health awareness topics like Mental Illness Awareness Week.

Compare With Alternatives

Doctors often consider SSRIs or SNRIs before MAOIs. Two well-known options are Sertraline and Effexor Xr. If you and your prescriber are weighing choices or plan changes, always follow recommended washout intervals to avoid dangerous interactions. Some patients also review budgets to Compare Nardil prices with other therapies.

Pricing and Access

We display transparent options so you can review the Nardil price alongside generics when available. Many customers look for Nardil Canadian pricing as part of their budgeting. This helps you understand expected pharmacy charges and review dispensing quantities.

Orders Ships from Canada to US with prescription validation. If you pay without insurance, you can still see current options before checkout. For privacy and security, our site uses encrypted checkout. To explore related conditions and therapies, visit Mental Health.

Availability and Substitutions

Supply can vary by manufacturer. If a specific brand is unavailable, your prescriber may recommend a suitable alternative or a generic. You can Order phenelzine tablets when your prescription allows. We cannot promise restock dates; your prescriber can guide a safe switch if needed.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults who understand interaction rules, can follow diet guidance, and have an established care plan. It may not be appropriate for those with certain medical conditions or those unable to manage food and drug restrictions.

• Multi-month fills: request longer supplies when appropriate
• Refill reminders: set alerts before you run low
• Budget review: compare Phenelzine price with other options
• Medication list: keep an updated list for every appointment
• Diet planning: prepare a low-tyramine plan before starting

Questions to Ask Your Clinician

• Is an MAOI the right class for my symptoms and history?
• Which foods and beverages should I strictly avoid?
• What washout periods apply if I need to change medicines?
• How will you monitor side effects and liver health?
• When should I contact the clinic about headaches or blood pressure concerns?
• Can we plan a maintenance schedule once I respond?

Authoritative Sources

• FDA DailyMed: Phenelzine Tablets
• Health Canada Drug Product Database

Ready when you are. Buy phenelzine online with prompt US shipping from Canada. Prescription required. This information is not a substitute for professional medical advice; always follow your prescriber’s directions.