Nifedipine XR Extended-Release Tablets for Hypertension and Angina

What Nifedipine XR Is and How It Works

Nifedipine XR is an extended-release form of nifedipine, a calcium channel blocker. It helps manage high blood pressure and chronic stable angina. Tablets release medicine slowly over the day for steady control with once-daily dosing. Many people compare options when shopping for nifedipine xr without insurance, and our team can help you place a safe order.

YouDrugstore is a licensed Canadian pharmacy based in Manitoba. Orders follow Canadian pharmacy standards, and a licensed pharmacist reviews prescriptions before dispensing. We offer brand and generic medicines at Canadian prices, and carry OTC health products. You can order online, and our friendly customer-service chat is available during posted office hours.

We also source through licensed and vetted partner pharmacies abroad to keep authentic brands available, expand selection, and keep pricing affordable.

Nifedipine reduces calcium entry into vascular smooth muscle. Arteries relax and widen. Blood pressure falls, and the heart needs less oxygen. The extended-release (XR) form avoids sharp peaks seen with short-acting tablets. Typical strengths include 30 mg, 60 mg, and 90 mg. Options like Mylan Nifedipine XR 30 mg are common.

Dosage and Usage

Follow the prescribed dose on the label. Clinicians often start with 30 mg once daily and adjust after 7–14 days. Some patients may need 60–90 mg daily. Do not use short-acting nifedipine for routine blood pressure control.

• Swallow extended-release tablets whole with water. Do not crush, split, or chew.
• Take at the same time each day. Take with or without food, but stay consistent.
• If a dose is missed, take it when remembered unless it is near the next dose. Do not double doses.
• Expect the shell of the tablet in the stool. That is normal for some XR designs.

Storage and travel:

• Store at 20–25°C (68–77°F). Keep in a dry place away from moisture and heat.
• Keep in the original bottle or blister until use. Protect from light.
• For travel, carry it in your hand luggage. Bring your prescription label and a small buffer supply.
• Keep out of reach of children and pets.

Benefits and Savings

Nifedipine XR lowers blood pressure and helps prevent angina episodes. Once-daily dosing supports adherence. The XR design offers steady levels through the day. Many patients see fewer peaks and troughs than with immediate-release forms.

Buying through YouDrugstore can cut costs versus typical US retail. Savings often range from 60–80%, especially on generic strengths like nifedipine xr 30 mg. Orders can be placed online, and you can track shipment updates by email. If you buy nifedipine xr online, our team supports you through checkout. We can also help if you pay cash or shop without insurance.

Side Effects and Safety

Most effects are mild and improve after dose adjustment. This is not a complete list.

• Common: headache, flushing, dizziness or lightheadedness, fatigue, nausea, heartburn, ankle or foot swelling, palpitations.
• Less common: constipation, gingival overgrowth, rash.
• Serious: fainting, severe low blood pressure, chest pain that worsens, shortness of breath, irregular heartbeat, signs of allergic reaction (hives, swelling, trouble breathing), severe skin reaction, or liver problems (dark urine, yellowing skin/eyes).

Use caution with strong CYP3A4 inhibitors or inducers. Grapefruit or grapefruit juice can raise levels and increase side effects. Azole antifungals, macrolide antibiotics, protease inhibitors, and some antidepressants may interact. Rifampin can reduce levels and blunt the effect. Combining with other blood pressure medicines can increase hypotension risk. People with severe aortic stenosis, cardiogenic shock, or unstable angina need careful evaluation. Extended-release nifedipine is not for acute hypertensive emergencies.

Onset Time

Blood pressure reduction begins within a few hours of the first XR dose. Peak effect often appears around 6 hours. The full response builds over days as steady-state is reached. Angina control may improve within the first week. Dose changes may need 1–2 weeks to show the final effect.

Compare With Alternatives

Other dihydropyridine calcium channel blockers include amlodipine and felodipine. Amlodipine is once daily and long-acting, with similar blood pressure results and a low risk of heart rate changes. It can cause ankle swelling, as can nifedipine XR. Felodipine ER is another once-daily option with comparable efficacy.

Non-dihydropyridine agents like diltiazem ER help with rate control in certain arrhythmias and angina, and also lower blood pressure. They may reduce heart rate and can interact with beta-blockers.

Brand versions exist, such as Adalat XL® and Procardia XL®. Generic nifedipine XR offers a cost-effective alternative with similar clinical outcomes when taken as prescribed.

Combination Therapy

Many adults need more than one medicine to reach blood pressure targets. Nifedipine XR often combines well with ACE inhibitors, ARBs, or thiazide diuretics. Beta-blockers may be used for angina control in selected patients. Clinicians individualize therapy based on comorbidities, kidney function, heart rate, and tolerance. Always share a full medication list, including supplements, to help avoid interactions.

Patient Suitability and Cost-Saving Tips

Nifedipine XR suits adults who need once-daily control of hypertension or chronic stable angina. It is not meant for sudden chest pain or hypertensive emergencies. People with severe aortic stenosis, recent unstable angina, or advanced heart failure need careful oversight. Those with significant liver disease may require dose adjustments and monitoring.

Practical ways to manage costs are available. Many patients lower the per-month price by choosing a 90-day supply. Bulk buy nifedipine xr options may reduce pharmacy handling fees and shipping costs per dose. You can turn on gentle reorder reminders in your account so you do not run out.

For current deals and bulk options, see our nifedipine xr coupon page. If you compare the nifedipine xr cash price across pharmacies, check tablet strength and pack size to keep the comparison fair.

You can place your order online or by phone where available. Our customer-service chat is available during posted office hours. Pharmacists are available to address medication questions before dispensing.

Authoritative Sources

Learn more from trusted references:

• Bayer product information for Adalat XL
• Health Canada Drug Product Database: Nifedipine entries
• FDA prescribing information for Procardia XL

YouDrugstore makes it simple to get the medicine you need at Canadian prices. Order today for careful pharmacist review, discreet packing, and prompt, express, cold-chain shipping when required.

This information is not a substitute for professional medical advice. Always follow your prescriber’s guidance and the instructions on your prescription label. Seek medical help for severe or unexpected symptoms.