Novomix® Penfill Cartridge for Premixed Insulin Aspart 30/70

What Novomix® Is and How It Works

Novomix Penfill Cartridge contains biphasic insulin aspart 30/70 for diabetes management. It combines 30% rapid-acting insulin aspart with 70% protamine-crystallized insulin aspart. The rapid part limits post-meal spikes, and the protamine part covers basal needs between meals. Typical use is once or twice daily with main meals. Many patients search for Novomix Penfill Cartridge online or need a Novomix cartridge price they can afford, including a Novomix cartridge without insurance option.

YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba, and licensed pharmacists review every prescription before dispensing.

We source through licensed, vetted international partner pharmacies to provide authentic brand medications, a wide selection, and fair pricing.

Novomix is a U-100 insulin delivered by subcutaneous injection using compatible reusable pens that accept Penfill cartridges. It is used in adults with type 2 diabetes and, in some cases, type 1 diabetes when a premixed regimen is appropriate. Injections are given under the skin of the abdomen, thigh, upper arm, or buttocks. Rotate injection sites to reduce skin changes. Learn more about the condition in our brief guide to Diabetes.

Insulin aspart starts working about 10–20 minutes after injection. The premixed formulation peaks roughly 1–4 hours after dosing and can last up to 24 hours in some users, though duration varies. Dosing is individualized and guided by blood glucose patterns, meal size, and activity.

Dosage and Usage

• Start and titrate under clinical supervision; common regimens are once or twice daily with main meals.
• Inject subcutaneously immediately before the meal, or shortly after if necessary.
• Use only with compatible reusable pens that accept Penfill cartridges (for example, Novo Nordisk NovoPen devices).
• Prepare the device: wash hands, attach a new needle, and prime the pen as directed.
• Inspect the insulin. The suspension should appear uniformly cloudy after gentle rolling and inversion.
• Choose an injection site in the abdomen, thigh, upper arm, or buttocks, and rotate sites.
• Deliver the prescribed dose, keep the needle in place for 6–10 seconds, and dispose of the needle safely.
• Missed dose: monitor glucose and follow the care plan provided by the prescriber. Do not double the next dose.
• Never share pens or needles. Do not inject intravenously or use in insulin pumps.

• Store unopened cartridges in the refrigerator at 2–8°C (36–46°F). Do not freeze.
• Keep away from heat and light. If frozen, discard.
• After first use, keep the cartridge in the pen at room temperature below 30°C (86°F) and use within the in-use period on the label.
• Do not refrigerate the pen with a cartridge in use.
• When traveling, carry spares in an insulated pouch with cool packs; keep a backup in a separate bag.
• Never place insulin in checked luggage. Carry a copy of the prescription for security checks.
• Inspect before each use. If clumps, particles, or color changes appear, do not use.

Benefits and Savings

Novomix provides mealtime and between-meal coverage in one injection. This can reduce daily injections compared with basal-bolus regimens. The Penfill format supports accurate dosing with compatible pens and can simplify daily routines for people with busy schedules.

Ordering from Canada often offers meaningful savings. Typical customers save 60–80% versus common US retail prices, which helps those comparing the Novomix 30 cartridge price or tracking the Novomix cartridge cost month to month. If paying without insurance, multi-month supplies can further lower the per-month cost.

Sign up for reorder reminders so future supplies arrive on time and glucose control stays consistent. Bulk options may reduce the Novomix cartridge out of pocket spend when prescribed for long-term therapy, and periodic site promotions can make a Novomix cartridge sale even more affordable.

To check offers, see our novomix penfill cartridge coupon page.

For background on Canadian pharmacy value and safety, you can review Why Choose A Canadian Pharmacy Store For Safe Medications.

Side Effects and Safety

• Hypoglycemia (shakiness, sweating, hunger, headache, fast heartbeat)
• Injection site redness, swelling, or itching
• Weight gain or peripheral edema
• Lipodystrophy or cutaneous amyloidosis at injection sites
• Rash or hypersensitivity reactions
• Blurred vision during early glucose improvement
• Low potassium (hypokalemia), especially with higher doses

Serious hypoglycemia can be dangerous. Adjustments are often needed when switching insulins, changing meal patterns, or during illness. Severe allergy is rare but requires urgent care. Hypoglycemia risk rises when Novomix is combined with insulin secretagogues such as sulfonylureas or when alcohol intake is high. Monitor potassium in patients at risk of hypokalemia.

Onset Time

Post-meal glucose often improves with the first doses because of the rapid-acting aspart component. The basal component supports fasting and between-meal control within the first few injections. Most people see steadier daily readings after 1–2 weeks as doses are adjusted. A1C changes are typically assessed after 8–12 weeks of stable dosing and monitoring.

Compare With Alternatives

Human NPH insulin is a basal option that can be paired with separate mealtime insulin. For those who prefer a human insulin approach, Novolin® Ge Nph Penfill Cartridge offers intermediate-acting coverage but requires additional prandial insulin for meals.

Mealtime-only insulins such as Humalog® Kwikpen (insulin lispro) are rapid-acting and are often used in a basal-bolus plan with a separate basal insulin. This offers fine-tuned control but usually means more injections than a premix like Novomix.

Regular insulin (short-acting) in vials, such as Novolin® Ge Toronto Vial, has a slower onset and longer tail than analog rapid insulins. Some patients use it based on cost or familiarity, but timing to meals is less flexible compared with insulin aspart.

Combination Therapy

• With metformin for type 2 diabetes, a common and complementary pairing.
• With SGLT2 inhibitors or DPP-4 inhibitors when additional control is needed.
• With sulfonylureas; consider dose adjustments to reduce hypoglycemia risk.
• With antihypertensives or statins as part of comprehensive cardiovascular risk management.

Patient Suitability and Cost-Saving Tips

Novomix 30 Penfill Cartridge suits adults who need both mealtime and intermediate coverage in one product. It is not for intravenous use, not for insulin pumps, and not for people with ongoing hypoglycemia or hypersensitivity to insulin aspart. Use with caution in renal or hepatic impairment and in older adults. Discuss dosing in pregnancy or breastfeeding with the prescriber.

Those comparing the Novomix 30 cartridge price or looking for a Novomix price without insurance can consider larger fills when appropriate, since multi-pack orders sometimes lower the per-cartridge price. Use the account dashboard to set simple reorder reminders so therapy is not interrupted.

Authoritative Sources

NovoMix 30 overview from Novo Nordisk (manufacturer)

Health Canada Drug Product Database: NovoMix 30 product listing

FDA label for insulin aspart (US reference information)

Order Novomix® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This page is educational and does not replace advice from a licensed healthcare professional. Always follow the treatment plan and product instructions provided with the prescription.