Nurtec® Orally Disintegrating Tablets for Migraine

Nurtec® ODT is a prescription medicine for the acute treatment and prevention of migraine in adults. This page explains what it is, how to use it, and important safety notes. You can compare the Nurtec ODT price without insurance and see how US shipping from Canada works for your order.

What Nurtec Is and How It Works

YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

This medicine contains rimegepant, a calcitonin gene-related peptide (CGRP) receptor antagonist. It helps block CGRP activity, which is involved in migraine attacks. The tablet dissolves on the tongue and can be taken without water. The Rimegepant brand name is well known for treating acute attacks and for episodic prevention. It is not an opioid and does not cause vasoconstriction like triptans.

For acute treatment, it may help relieve headache and associated symptoms such as nausea or sensitivity to light and sound. For prevention, it is taken on a schedule to reduce the number of monthly attacks. Always follow your prescriber’s directions and the official Patient Information.

Who It’s For

This treatment is for adults with migraine, with or without aura. It is used both to treat attacks when they occur and to help prevent episodic migraine.

People with a history of severe liver disease or end-stage kidney disease should not use it. If you have moderate liver problems or reduced kidney function, discuss risks with your clinician. It has not been established in children or in pregnancy or breastfeeding. Tell your healthcare professional about all medical conditions and all medicines, including over-the-counter products and supplements.

Dosage and Usage

Use as directed by your prescriber and the label. For acute treatment, the standard adult dose is one tablet taken when a migraine begins. Do not take more than one dose in 24 hours. For prevention of episodic migraine, the usual schedule is one tablet every other day.

How to take: with dry hands, peel back the blister foil (do not push the tablet through), place the orally disintegrating tablet on or under the tongue, and allow it to dissolve. It can be taken without water and with or without food. If you use this therapy with other medicines for migraine, ask your clinician about timing and spacing. Rimegepant 75 mg is the typical strength used for both acute and preventive regimens.

Avoid taking another dose within the same day. If your headaches are frequent, speak with your prescriber about a preventive plan and how often you can safely use acute doses.

Strengths and Forms

This product is available as orally disintegrating tablets in unit-dose blister packs. Availability can vary by supplier and country.

• Rimegepant 75 mg ODT

Packaging helps protect tablets from moisture. Do not remove a dose until you are ready to take it.

Missed Dose and Timing

If you are taking it for prevention and miss a scheduled every-other-day dose, take it when you remember unless it is almost time for the next planned dose. Then skip the missed dose and resume your usual schedule. Do not double up. For acute treatment, if your symptoms improve and return later the same day, do not repeat a dose that day. Ask your prescriber what to do if attacks occur on consecutive days.

Storage and Travel Basics

Store at room temperature in the original blister to protect from moisture. Keep dry and handle with clean, dry hands. Keep out of reach of children and pets. Do not use tablets that are cracked, discolored, or stuck to the foil.

Travel tips: keep doses in carry-on luggage with a copy of your prescription. Use a small pill case for the day of travel, but leave most tablets sealed in their blisters. Check local regulations when crossing borders and allow extra time for security screening.

Benefits

As a CGRP receptor antagonist, this therapy may reduce headache pain and other migraine symptoms without the vasoconstriction seen with triptans. The orally disintegrating format is convenient if you have nausea or cannot take water easily. A single 75 mg tablet per attack is straightforward, and an every-other-day schedule can support prevention in episodic migraine. Many people like having one medicine that can address both immediate relief and ongoing prevention.

Side Effects and Safety

• Nausea
• Stomach pain or indigestion
• Upset stomach or burping
• Dizziness
• Fatigue
• Mild rash

Serious allergic reactions can occur, sometimes delayed, with symptoms like swelling of the face, lips, tongue, or throat; trouble breathing; and widespread rash. Stop the medicine and get urgent care if these occur. Liver-related issues have been reported rarely; contact your healthcare professional if you notice unusual fatigue, dark urine, or yellowing of skin or eyes. Side effects of Nurtec vary; read the Medication Guide for full information.

Drug Interactions and Cautions

This therapy is metabolized by CYP3A4 and transported by P-gp/BCRP. Strong CYP3A4 inhibitors (such as certain antifungals or macrolide antibiotics) and strong CYP3A4 inducers (such as some seizure medicines or rifampin) may change levels. Potent P-gp or BCRP inhibitors can increase exposure. Alcohol may worsen dizziness or stomach upset. Do not combine with another dose within 24 hours. Tell your prescriber about all medicines, vitamins, and herbal products you take so they can assess interaction risk.

What to Expect Over Time

For acute use, many patients report relief the same day. Preventive use on an every-other-day schedule may help reduce the number of monthly migraine days over time. Your experience can vary. Keep a headache diary to track triggers, doses, and response. Share your notes at follow-up visits to refine your plan. If attacks remain frequent or severe, your clinician may adjust your broader regimen or explore other options.

Compare With Alternatives

Other options are available. A fellow CGRP receptor antagonist, Ubrelvy, is taken as needed for acute attacks and may suit people who prefer a swallowable tablet. A triptan such as Zolmitriptan can be effective for many, though triptans cause vasoconstriction and are not suitable for some cardiovascular conditions. Your prescriber can help you weigh class differences, prior response, and comorbidities.

Pricing and Access

We offer Canadian pricing for US patients with a valid prescription. You can review availability, compare the Nurtec ODT price, and decide on the best quantity for your needs. If you’re looking for additional ways to save, check our current offers on the Promotions page.

Ships from Canada to US with pharmacy fulfillment. For migraine education, visit our Migraine condition hub and browse the Neurology category for related therapies.

Availability and Substitutions

Supply can vary. If stock is limited, your prescriber may recommend another CGRP antagonist or a triptan. There is currently no Nurtec ODT generic approved in the US. Ask your clinician before switching classes, especially if you have cardiovascular risk factors or multiple preventive medicines.

Patient Suitability and Cost-Saving Tips

You may be a candidate if you have episodic migraine and need either acute relief, prevention, or both. It may not be appropriate if you have severe liver impairment or end-stage kidney disease. Share your full medication list so your clinician can check for interactions. If you are pregnant, planning pregnancy, or breastfeeding, discuss potential risks and alternatives.

Cost tips: consider multi-month quantities if appropriate, which can reduce per-tablet costs and help avoid gaps. Set refill reminders tied to your every-other-day schedule. If nausea is common for you, keep an antiemetic on hand so you can take your dose promptly. For related support medicines, see Ondansetron for nausea and Propranolol as a preventive option in suitable patients, per your prescriber’s advice.

Questions to Ask Your Clinician

• Acute vs preventive plan: how should I use this for both?
• Dosing limits: how many days per month are appropriate?
• Interactions: do any of my current medicines conflict?
• Response tracking: what goals should I set for relief and prevention?
• Switching options: if this is not effective, what classes come next?
• Safety: what symptoms should prompt a call or urgent care?
• Travel: how many tablets should I carry and how should I pack them?

Authoritative Sources

• Manufacturer Product Page
• FDA DailyMed Prescribing Information
• Health Canada Drug Product Database

Ready to get started? Place your order with prompt shipping and US delivery from Canada. Prescription required; encrypted checkout. This content is for general information and does not replace your clinician’s advice.