Omvoh® Injection for Ulcerative Colitis

Omvoh® is a prescription biologic for adults with moderate to severe ulcerative colitis. It targets a key inflammatory pathway to help reduce disease activity. We support US delivery from Canada and provide transparent options for those comparing Omvoh cost without insurance.

What Omvoh Is and How It Works

Omvoh is mirikizumab, a monoclonal antibody that binds the p19 subunit of interleukin-23. By blocking IL‑23 signaling, the treatment may decrease inflammation in the colon. YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

This therapy is started by a prescriber experienced with inflammatory bowel disease. Mirikizumab injection is used after evaluating your condition and medical history. It can be considered when symptoms persist despite other approved options.

Who It’s For

This medicine is indicated for adults with moderately to severely active ulcerative colitis. It may be used after previous treatments such as corticosteroids, immunomodulators, or other biologics have not worked well enough or were not tolerated. People with active serious infections, untreated tuberculosis, or a history of severe hypersensitivity to this product should avoid it.

Your clinician may screen for TB and review your vaccines before starting therapy. Live vaccines are not recommended during treatment. For more on the condition, see our resource on Ulcerative Colitis.

Dosage and Usage

The induction phase typically begins with an intravenous regimen prescribed by your clinician. After induction, ongoing maintenance is given as an Omvoh subcutaneous injection every four weeks. The exact schedule follows the official label and your prescriber’s direction.

Administration basics include rotating injection sites on the abdomen or thigh and allowing the pen to reach room temperature per the instructions. Do not inject into tender, bruised, or scarred skin. If a caregiver assists you, they should review the patient information leaflet and receive training. For general pen technique, our guide on Ozempic Pen Tips covers helpful steps that also apply to many single-use pens.

Never change your dose schedule without your prescriber’s advice. If you are unsure about timing, consult the package insert or speak with a healthcare professional.

Strengths and Forms

Maintenance therapy is supplied as a ready-to-use prefilled device for at-home administration. The commonly available presentation is Mirikizumab 100 mg/mL for the pen or syringe. Induction is given by intravenous infusion under medical supervision.

Devices may vary by market. Some patients prefer a prefilled pen, while others use the prefilled syringe. Availability can change; your prescriber will select the presentation that fits your plan.

Missed Dose and Timing

If a maintenance dose is missed, take it as soon as you remember, then resume the regular schedule as directed by your clinician. Do not double up to make up a missed dose. If you are uncertain, review the patient leaflet and contact your prescriber or pharmacist for guidance. Keep a calendar or reminder system to support consistent use.

Storage and Travel Basics

Store this medicine in the refrigerator in the original carton to protect it from light. Do not freeze, and do not shake. When traveling, keep the pen in an insulated bag with cold packs to maintain the recommended temperature range. Avoid placing it directly on ice. If you need to bring it through airport security, keep it with the pharmacy label and your prescription details.

Allow the device to warm to room temperature only as recommended by the instructions before use. If the solution looks discolored or contains particles, do not inject it. Keep all medicines out of reach of children.

Pen Handling and Sharps Disposal

The Omvoh prefilled pen is designed for single use. Read the Instructions for Use before your first injection. Wash your hands, prepare a clean surface, and choose an appropriate site. After injecting, place the used pen or syringe into an approved sharps container.

Follow local regulations for sharps disposal. Never throw loose needles into household trash or recycling. For a step-by-step overview of single-use devices, see our quick guide Inject Mounjaro for general injection tips. If you ever experience a device malfunction, contact your pharmacist and the manufacturer for next steps.

Benefits

This therapy targets IL‑23, a pathway associated with chronic intestinal inflammation. For suitable adults, the treatment may reduce symptoms and support maintenance of response according to approved labeling. Prefilled devices offer at-home dosing on a regular schedule after induction is complete. A consistent four-week interval can simplify planning compared with more frequent injections.

Side Effects and Safety

• Upper respiratory tract infection
• Headache
• Injection site reactions
• Joint pain
• Rash

Serious risks can include severe hypersensitivity and serious infections. Your prescriber may test for latent tuberculosis before starting therapy and monitor for signs of infection during treatment. If you develop fever, persistent cough, shortness of breath, or severe abdominal pain, seek medical attention. People using insulin or sulfonylureas should discuss hypoglycemia monitoring when other medicines are adjusted, even though this treatment is not a glucose‑lowering drug.

Drug Interactions and Cautions

Tell your clinician about all medicines you take, including immunosuppressants, biologics, and corticosteroids. Combining multiple immunomodulators can raise infection risk. Live vaccines should be avoided during treatment; non-live vaccines may be considered per guidelines. If you are pregnant, planning pregnancy, or breastfeeding, discuss potential risks and benefits.

Report any history of recurrent infections, TB exposure, or prior hypersensitivity to monoclonal antibodies. Keep all scheduled lab tests and clinic follow-ups as advised.

What to Expect Over Time

Induction is managed in a clinical setting, followed by planned at-home maintenance. Your prescriber will assess symptoms and may use endoscopy or biomarkers to evaluate response over time. Adherence to the four‑week dosing interval is important. Keep a written log of injection dates, lot numbers, and any side effects. If expectations are not met, your plan may be reassessed according to the label and clinical judgment.

Compare With Alternatives

Other approved options for ulcerative colitis include ustekinumab and tofacitinib. For patients considering another biologic, Stelara® Prefilled Syring is an IL‑12/23 inhibitor with subcutaneous maintenance dosing. For an oral small‑molecule alternative, Xeljanz® XR is a JAK inhibitor used in adults with moderate to severe disease. Your prescriber can help determine which mechanism aligns with your history and goals.

Pricing and Access

We offer transparent options to help you compare the Omvoh Injection price with Canadian-sourced supply. If you plan to Order Omvoh online, our team will verify your prescription before processing. US shipping from Canada is available with tracking. For general condition listings, you can also browse Other categories to see related therapies and supports.

Looking for seasonal offers or manufacturer savings programs? Visit our Promotions page for current opportunities where applicable. We do not publish dollar amounts here; see the product page for current pricing details and availability.

Availability and Substitutions

Supply can vary. If a specific device is temporarily unavailable, a prescriber may recommend an alternative presentation or a different class with similar goals. We cannot provide restock dates in advance. Your pharmacist can discuss comparable options if your clinician requests a change.

Patient Suitability and Cost-Saving Tips

Candidates include adults with confirmed ulcerative colitis who need a targeted therapy and have been assessed for infections, TB, and vaccine status. Those with active serious infections or prior severe hypersensitivity are generally not candidates. If costs are a concern, ask your prescriber about multi‑month fills to reduce refill frequency. Setting refill reminders can help maintain steady therapy.

Consider coordinating clinic visits for induction and follow-up on the same day to minimize trips. Keep a consistent pharmacy profile to avoid duplication of services. Our checkout uses encrypted processing to protect your information.

Questions to Ask Your Clinician

• Induction plan: What is my infusion schedule and monitoring plan?
• Home dosing: Who will train me for at‑home injections?
• Vaccines: Which vaccines should I get before starting treatment?
• Infections: What symptoms should prompt a call or visit?
• Lab tests: Which labs or stool tests will we track over time?
• Travel: How should I pack and store my device during trips?
• Alternatives: If this does not suit me, what options come next?

Authoritative Sources

US Prescribing Information (Eli Lilly)

FDA DailyMed: Omvoh

Health Canada Drug Product Database

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