How does this medicine lower testosterone?

It blocks the pituitary GnRH receptor, which reduces signals to the testes that drive testosterone production. By antagonizing this receptor directly, it avoids the initial testosterone rise seen with some other approaches. Your clinician will confirm that androgen-deprivation is appropriate for your cancer stage and will monitor labs such as testosterone and PSA to assess response over time.

How is the first dose started and then continued?

Treatment typically begins with a higher dose on day one, followed by one tablet daily thereafter. Take it at about the same time each day, with or without food, and swallow tablets whole. If you miss a dose, do not double up. Follow the official label for detailed instructions and ask your healthcare professional if you have questions about timing or coordinating with other therapies.

What common side effects should I expect?

Frequently reported effects include hot flashes, tiredness, bowel changes such as constipation or diarrhea, musculoskeletal pain, decreased libido, and possible changes in liver enzymes. Not everyone experiences side effects. Serious issues like severe allergic reactions, heart rhythm changes, or significant dizziness need urgent care. Tell your prescriber about any persistent or severe symptoms and review medicine guides for full safety details.

Are there important drug interactions?

Yes. This treatment is affected by P-glycoprotein transport. Strong P-gp inhibitors can increase exposure, and combined P-gp with strong inducers can reduce exposure. Your clinician may adjust timing if certain interacting drugs cannot be avoided. Share all prescription and nonprescription products, vitamins, and herbal supplements you use. Avoid starting or stopping medicines without discussing them with your prescriber first.

Can I take it with food or alcohol?

You can take your daily tablet with or without food. Moderate alcohol is not specifically contraindicated, but alcohol may worsen some side effects like dizziness or fatigue. If you drink, do so cautiously and note any symptom changes. People with liver disease or on other hepatotoxic medicines should ask their clinician about alcohol use during therapy.

What lab tests will be monitored?

Your care team may track testosterone and PSA to evaluate treatment effect. They may also review electrolytes, liver function, and glucose or lipids depending on your health profile and concurrent medicines. If you have cardiac risk factors or take QT-prolonging drugs, periodic ECGs may be considered. Monitoring plans are individualized; follow your clinician’s guidance.

How long will I stay on androgen-deprivation therapy?

Duration depends on cancer stage, response, and your overall plan, which may include other treatments. Some individuals remain on therapy long term, while others change regimens as disease status evolves. Your prescriber will outline goals and reassess at regular visits. Keep open communication about side effects, goals of care, and any new medicines or conditions that arise.

Promotion

Orgovyx

Orgovyx® Tablets for Advanced Prostate Cancer

Prostate Cancer

Please note: a valid prescription is required for all prescription medication.

Stock up and Save - Get 20% off when you buy 3 or more of any one product. Use code SAVE20 at checkout.

Coupon code cannot be combined with other offers. Sale applies to all products originating from Canada. Maximum allowable quantity equal to a 90 day supply per single order.

Price:

$566.99

Secure Encrypted Payments

What Orgovyx Is and How It Works

Orgovyx® is a prescription tablet for men with advanced prostate cancer. It lowers testosterone by blocking the pituitary GnRH receptor, which reduces testicular androgen production. We provide US delivery from Canada so you can access pharmacy-filled medication even if paying without insurance. YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

This medicine is a GnRH receptor antagonist. It reduces testosterone without the initial hormone surge that can occur with some other androgen-deprivation approaches. The treatment is taken by mouth, which avoids office injections and may fit daily routines better for many patients.

Who It’s For

This therapy is indicated for adults with advanced or metastatic prostate cancer where androgen-deprivation is appropriate. It is not approved for women or children. People with a history of severe allergic reaction to any component should avoid it.

Discuss your cardiac history with your prescriber. This medicine may prolong the QT interval, and caution is advised in those with risk factors or who take other QT-prolonging drugs. Your clinician may review electrolytes and other medical conditions that could affect safety. See our condition hub for broader context on Prostate Cancer and related care within Oncology.

Dosage and Usage

Therapy begins with a higher first-day dose, followed by one tablet once daily. Take it at about the same time each day, with or without food. Swallow tablets whole with water. Do not crush, split, or chew.

If you are starting or stopping medicines that affect transport or metabolism, your prescriber may adjust timing to reduce interaction risks. Always follow your clinician’s instructions and consult the official product information for detailed directions. Consistent daily dosing supports sustained testosterone suppression.

Strengths and Forms

The product is supplied as film-coated tablets in a single strength of 120 mg. Blister packaging helps protect tablets from moisture until use. Availability can vary by supplier or jurisdiction.

Pack sizes may differ. If you are comparing sources, review strength, pack quantity, and dispensing pharmacy to ensure a like-for-like evaluation.

Missed Dose and Timing

If you miss a dose and it is within a relatively short window, take it when remembered and resume your usual schedule the next day. If it has been a longer gap, skip the missed dose and take the next one at the regular time. Do not double up. If you miss several doses, contact your healthcare professional for guidance. Refer to the official label for exact instructions.

Storage and Travel Basics

Store tablets at room temperature in the original packaging until use. Keep them dry, away from excess heat and moisture, and out of reach of children and pets. Do not use tablets that are damaged or past the labeled expiry date.

For travel, keep the pharmacy-labeled container in your carry-on. Bring a copy of your prescription and a medication list for security checks. If you cross time zones, plan dosing to maintain your daily rhythm. A pill organizer and phone reminders can help reduce missed doses.

Benefits

This therapy provides androgen-deprivation through a once-daily oral tablet. It can avoid the initial testosterone surge associated with certain other options. Many patients appreciate not needing injections. The class may support PSA reductions when used as directed, though individual responses vary.

Your prescriber may combine this medicine with additional prostate cancer treatments when clinically appropriate. Always follow your care plan and keep scheduled lab checks.

Side Effects and Safety

Hot flashes
Fatigue or tiredness
Constipation or diarrhea
Musculoskeletal pain
Headache or dizziness
Elevated liver enzymes
Decreased libido

Serious effects can include significant allergic reactions, cardiovascular concerns including QT prolongation, and metabolic changes such as changes in blood sugar or lipids. Report chest pain, shortness of breath, severe dizziness, fainting, swelling of the face or throat, or severe rash. Those on insulin or sulfonylureas should watch for low blood sugar when therapy is adjusted. Use is prescription required and verified.

Drug Interactions and Cautions

The treatment is a substrate of P-glycoprotein. Strong P-gp inhibitors may raise levels, and combined P-gp with strong inducers may lower levels. Your prescriber may adjust timing when certain interacting medicines cannot be avoided. Examples include some macrolide antibiotics, certain anticonvulsants, rifamycins, and herbal products like St. John’s wort. Review all medicines, including over-the-counter agents and supplements, with your clinician.

Those with a history of heart rhythm issues, electrolyte abnormalities, or taking other QT-prolonging drugs may require closer monitoring. This medicine is not indicated in pregnancy. Patients with partners who could become pregnant should discuss contraception during treatment and for the advised interval after stopping.

What to Expect Over Time

With consistent daily use, testosterone and PSA are expected to decline relative to baseline as part of androgen-deprivation goals. Your clinician will track labs and assess symptoms over time. Some side effects may appear early, while others can develop with longer use. Bone health and cardiovascular risk may be addressed through lifestyle and supportive measures where needed.

Adherence helps sustain suppression. Set phone reminders, align dosing with a daily habit, and arrange timely refills to avoid gaps.

Compare With Alternatives

Oral and injectable androgen-deprivation options exist. Androgen receptor inhibitors may be added in selected cases. If your clinician recommends an oral AR inhibitor, you can review Nubeqa® or Zytiga® for labeled uses and differences. For individuals actively comparing options, tools to Compare Orgovyx prices can help frame budget discussions with your care team.

To understand how antagonist therapy differs from agonist injections, you may find this overview helpful: Zoladex Cost Usage Side Effects. For broader context on systemic therapies, see our Cancer Drugs List.

Pricing and Access

We dispense from licensed Canadian pharmacies with transparent checkout. If you are reviewing Orgovyx price, remember that pack size, dispensing pharmacy, and applicable fees influence totals. We also show Relugolix tablets cost so you can compare options under your prescriber’s guidance. Ships from Canada to US with careful fulfilment. Visit our Promotions page for current offers.

We accept valid prescriptions from your clinician. You can upload your script during checkout or ask us to contact your prescriber. Questions on insurance reimbursement or receipts for submission can be directed to our pharmacy team.

Availability and Substitutions

Supply can vary by manufacturer and pack size. If a specific presentation is temporarily unavailable, your prescriber may recommend an alternative approved therapy that suits your treatment plan. Interest in Relugolix 120 mg price is common; see our Pricing and Access section for the latest details and contact our team for current supply information.

Patient Suitability and Cost-Saving Tips

This medicine may suit adults who prefer an oral approach to androgen-deprivation and who can commit to daily dosing. It may not suit people with significant interaction risks, certain rhythm disorders, or severe hepatic issues without close monitoring. Always review your full medical history with your healthcare professional.

To manage Orgovyx cost, consider multi-month fills when appropriate, which can reduce per-fill fees and help maintain adherence. Set refill reminders before travel or holidays. Keep copies of prescriptions for smooth refills. Ask your clinician if any labs or visits can be coordinated to streamline care.

Questions to Ask Your Clinician

Is an oral GnRH antagonist appropriate for my disease stage?
How will you monitor testosterone, PSA, and safety labs?
Do any of my current medicines raise interaction concerns?
What lifestyle steps support bone and heart health during therapy?
How long might I stay on this treatment within my plan?
What are my options if I experience side effects?

Authoritative Sources

Manufacturer Website FDA DailyMed Prescribing Information Health Canada Drug Product Database

Ready to proceed? Order Orgovyx online with secure checkout and prompt, express shipping for US shipping from Canada. This page is informational and does not replace medical advice from your clinician.

Express Shipping - from $25.00

Shipping with this method takes 3-5 days

Prices:

Dry-Packed Products $25.00
Cold-Packed Products $35.00

Shipping Countries:

United States (all contiguous states**)
Worldwide (excludes some countries***)

Standard Shipping - $15.00

Shipping with this method takes 5-10 days

Prices:

Dry-Packed Products $15.00
Not available for Cold-Packed products

Shipping Countries:

United States (all contiguous states**)
Worldwide (excludes some countries***)

View All FAQs

How does this medicine lower testosterone?
It blocks the pituitary GnRH receptor, which reduces signals to the testes that drive testosterone production. By antagonizing this receptor directly, it avoids the initial testosterone rise seen with some other approaches. Your clinician will confirm that androgen-deprivation is appropriate for your cancer stage and will monitor labs such as testosterone and PSA to assess response over time.
How is the first dose started and then continued?
Treatment typically begins with a higher dose on day one, followed by one tablet daily thereafter. Take it at about the same time each day, with or without food, and swallow tablets whole. If you miss a dose, do not double up. Follow the official label for detailed instructions and ask your healthcare professional if you have questions about timing or coordinating with other therapies.
What common side effects should I expect?
Frequently reported effects include hot flashes, tiredness, bowel changes such as constipation or diarrhea, musculoskeletal pain, decreased libido, and possible changes in liver enzymes. Not everyone experiences side effects. Serious issues like severe allergic reactions, heart rhythm changes, or significant dizziness need urgent care. Tell your prescriber about any persistent or severe symptoms and review medicine guides for full safety details.
Are there important drug interactions?
Yes. This treatment is affected by P-glycoprotein transport. Strong P-gp inhibitors can increase exposure, and combined P-gp with strong inducers can reduce exposure. Your clinician may adjust timing if certain interacting drugs cannot be avoided. Share all prescription and nonprescription products, vitamins, and herbal supplements you use. Avoid starting or stopping medicines without discussing them with your prescriber first.
Can I take it with food or alcohol?
You can take your daily tablet with or without food. Moderate alcohol is not specifically contraindicated, but alcohol may worsen some side effects like dizziness or fatigue. If you drink, do so cautiously and note any symptom changes. People with liver disease or on other hepatotoxic medicines should ask their clinician about alcohol use during therapy.
What lab tests will be monitored?
Your care team may track testosterone and PSA to evaluate treatment effect. They may also review electrolytes, liver function, and glucose or lipids depending on your health profile and concurrent medicines. If you have cardiac risk factors or take QT-prolonging drugs, periodic ECGs may be considered. Monitoring plans are individualized; follow your clinician’s guidance.
How long will I stay on androgen-deprivation therapy?
Duration depends on cancer stage, response, and your overall plan, which may include other treatments. Some individuals remain on therapy long term, while others change regimens as disease status evolves. Your prescriber will outline goals and reassess at regular visits. Keep open communication about side effects, goals of care, and any new medicines or conditions that arise.