Perindopril/Amlodipine (Viacoram®) Tablets for Hypertension

What Perindopril/Amlodipine Is and How It Works

Perindopril/Amlodipine is a fixed-dose combination tablet for high blood pressure. It pairs an ACE inhibitor (perindopril) with a calcium channel blocker (amlodipine). Doctors use it in adults when one agent alone does not control blood pressure well, or to simplify a two-drug plan into a single pill. People often search for perindopril amlodipine without insurance to compare costs. Typical dosing is once daily.

The perindopril component is often the arginine salt. You may see terms like perindopril arginine amlodipine on labels. Amlodipine relaxes vessel walls, and perindopril lowers angiotensin activity and reduces aldosterone effects. Together, they help reduce vascular resistance and improve blood pressure control.

YouDrugstore is a licensed Canadian pharmacy in Manitoba. We meet Canadian pharmacy standards, and a licensed pharmacist reviews each prescription before dispensing. We offer brand and generic medicines at Canadian prices and also carry OTC health products. Ordering is simple online, and our customer-service chat is available during posted office hours.

We also work with vetted, licensed partner pharmacies abroad to supply authentic brands and a broad selection at fair pricing. The combination is sold under brand names in some markets. Viacoram® is a known brand name, and some regions use Acerycal®. Naming can vary by country and manufacturer.

Dosage and Usage

The exact dose depends on prior therapy and blood pressure goals. Common strengths in many markets include perindopril arginine/amlodipine 3.5/2.5 mg, 3.5/5 mg, 7/5 mg, and 7/10 mg. Some listings reference formats like perindopril amlodipine 10 5, perindopril amlodipine 5 5, or perindopril amlodipine 7 5mg, but available strengths vary by country and manufacturer.

• Start: clinicians may begin with a lower-strength tablet if patients are ACE inhibitor or CCB naive.
• Titration: adjust every 2–4 weeks based on response and tolerance.
• Administration: take once daily at the same time, with or without food. Swallow whole.
• Missed dose: take the next scheduled dose at the usual time. Do not double up.
• Switching: when switching from separate agents, choose the closest matching fixed-dose strength.

• Storage: store at 15–30°C in a dry place, away from heat and moisture.
• Travel: keep tablets in the original labeled container in carry-on bags.
• Refills: allow time for pharmacy review and shipping before running low.

Perindopril 10mg refers to the base strength for single-ingredient tablets; perindopril arginine amounts differ by salt. If unsure about equivalence, a pharmacist can clarify labeling and strengths.

Benefits and Savings

Combining perindopril and amlodipine in one tablet improves adherence and convenience. The regimen supports steady, 24-hour blood pressure control. Many patients who need two agents prefer a single daily tablet to simplify routines.

Buying from Canada can reduce costs significantly. Typical savings are 60–80% versus usual US pricing for the same therapy. This can help those paying cash. People comparing the perindopril amlodipine price or the perindopril amlodipine cost find that Canadian options offer value. Cost relief also matters for those managing treatment without insurance.

YouDrugstore offers both brand and generic options when available, and our team can help with product selection questions during office hours.

Side Effects and Safety

Most people tolerate the medicine well. ACE inhibitors and dihydropyridine calcium channel blockers have known effects.

• Common: ankle swelling, flushing, headache, dizziness, fatigue, cough, and palpitations.
• Gastrointestinal: nausea, abdominal discomfort, or diarrhea.
• Laboratory: mild increases in potassium or creatinine.
• Blood pressure: lightheadedness can occur when standing up quickly.

• Serious: angioedema (swelling of face, lips, tongue), severe hypotension, kidney problems, or liver issues.
• Allergic reactions: rash, severe itching, or breathing trouble need urgent care.
• Drug interactions: potassium salts, potassium-sparing diuretics, NSAIDs, lithium, and strong CYP3A4 inhibitors can affect safety.
• Food interactions: grapefruit or grapefruit juice may increase amlodipine levels.

ACE inhibitors can cause angioedema in rare cases. Risk is higher in those with a past episode. Pregnancy risk is significant in the second and third trimesters, and the combination is not used during those periods. People with bilateral renal artery stenosis, severe hypotension, or known hypersensitivity to either component need alternative therapy. Dose adjustments and closer monitoring may be needed in older adults or in renal impairment.

Onset Time

Blood pressure usually begins to improve within the first week. A fuller effect often appears after 2–4 weeks at a stable dose. If the response is insufficient, clinicians may up-titrate at safe intervals. Edema from amlodipine, if it occurs, can appear early and may be dose related.

Compare With Alternatives

Several combination options exist for hypertension. Viacoram® is one branded version pairing perindopril and amlodipine. In some regions, the viacoram brand name is used widely. Brands like Acerycal® may also be referenced in certain countries. Terminology such as perindopril arginine amlodipine brand name reflects this regional variation.

Other fixed-dose combinations include benazepril/amlodipine (Lotrel) and valsartan/amlodipine (Exforge). Patients who do not tolerate ACE inhibitors might use an ARB plus amlodipine instead. Perindopril/indapamide is another pathway for patients who need a diuretic, but it does not include amlodipine. Terms like indapamide and amlodipine, amlodipine indapamide, or perindopril indapamide amlodipine often arise during comparisons, though they refer to different regimens.

Combination Therapy

This tablet already contains two agents. It is not combined with other ACE inhibitors or other dihydropyridine CCBs. Clinicians may add a thiazide or thiazide-like diuretic when further control is needed. Potassium levels and renal function are monitored when adding agents, particularly if potassium-sparing drugs or supplements are part of the plan.

Some patients previously on separate tablets shift to a matching fixed-dose strength to reduce pill burden. Those exploring perindopril plus amlodipine often value the once-daily schedule.

Patient Suitability and Cost-Saving Tips

This combination suits adults with essential hypertension who need two agents. It may also fit those with stable angina where amlodipine offers symptom relief. It is avoided in pregnancy after the first trimester, in a history of ACE inhibitor–related angioedema, or with known hypersensitivity. People with severe liver disease or advanced renal disease need individualized assessment.

Ways to reduce cost include selecting an available generic, ordering a multi-month supply when appropriate, and using our reorder reminders to avoid last-minute purchases. If you are looking for a perindopril amlodipine discount, see our current offers and bulk options. Many shoppers also compare the perindopril amlodipine cash price across strengths. Terms such as apo perindopril amlodipine can appear on Canadian generic labels, and availability can change by manufacturer.

If you want to buy perindopril amlodipine online, YouDrugstore makes it simple to upload or send your prescription. Our team can assist with brand selection and strength questions during posted hours.

Authoritative Sources

See the manufacturer and regulator information for further details:

• Servier information on cardiometabolic products
• Health Canada Drug Product Database entry for Viacoram
• FDA Amlodipine Prescribing Information

YouDrugstore is here to help you access treatment at Canadian prices. Our licensed Manitoba pharmacy reviews prescriptions carefully and ships to the US with prompt, express, cold-chain shipping as needed.

This content is for general information. It does not replace advice from your own healthcare professional. Always follow your prescriber’s directions and the patient leaflet that comes with your medicine.