Viacoram® (Perindopril/Amlodipine) Uses, Strengths, and Savings

What Perindopril/Amlodipine Is and How It Works

Perindopril/amlodipine is a once-daily tablet that treats high blood pressure. It combines an ACE inhibitor (perindopril) with a calcium-channel blocker (amlodipine). This dual approach relaxes blood vessels, lowers vascular resistance, and reduces blood pressure. You can order perindopril amlodipine 10 5 without insurance, with choices across common strengths.

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Perindopril blocks angiotensin-converting enzyme, which reduces angiotensin II and aldosterone. This lowers vasoconstriction and fluid retention. Amlodipine blocks L-type calcium channels in vascular smooth muscle, which relaxes arteries and improves blood flow. Combined, perindopril and amlodipine provide complementary blood-pressure control and may reduce dose-limiting side effects seen with higher-dose monotherapy.

Tablets come in multiple strengths. Options vary by salt form (perindopril erbumine vs perindopril arginine). Common pairs include 5/5, 10/5, 10/10, and 7/5 mg. In some markets, perindopril arginine amlodipine 5 5 and 7/5 mg are typical. The perindopril amlodipine brand name you may see is Viacoram, and Acerycal is used in some regions. Apo perindopril amlodipine is a common generic listing.

This medicine is indicated for adults with essential hypertension, especially when blood pressure is not adequately controlled by either perindopril or amlodipine alone. It is taken by mouth once daily, with or without food.

Dosage and Usage

• Take one tablet by mouth once daily, at the same time each day.
• Swallow whole with water. Do not crush or split unless your prescriber advises.
• Starting dose depends on prior therapy. If new to both, prescribers often start at a lower strength and titrate after 2–4 weeks.
• Common strengths include perindopril amlodipine 5 5, perindopril amlodipine 10 5, perindopril amlodipine 10 10, and perindopril amlodipine 7 5mg. The exact pairing depends on the perindopril salt used.
• If switching from monotherapy (perindopril 10mg or amlodipine 5–10 mg), a prescriber may choose the nearest equivalent combination strength.
• Missed dose: take it when remembered the same day. If close to the next dose, skip the missed dose and resume the regular schedule. Do not double up.
• Limit alcohol, which can enhance blood-pressure lowering and dizziness.
• Check blood pressure at home during initiation and titration as directed by your care team.
• Tell your prescriber about potassium supplements, potassium-sparing diuretics, NSAIDs, lithium, or other medicines that may interact.

• Store tablets at 20–25 °C (68–77 °F); brief 15–30 °C (59–86 °F) excursions are usually acceptable.
• Keep in the original container to protect from moisture and light.
• Do not store in a bathroom. Keep out of reach of children and pets.
• For travel, carry in your hand luggage with the pharmacy label attached.
• Avoid heat in cars. Use a small insulated pouch if needed.
• If a tablet looks damaged or discolored, do not use it.

Benefits and Savings

The combination of perindopril and amlodipine lowers blood pressure through two pathways. Many people reach targets with one daily tablet, which improves adherence. Using a fixed-dose combination can reduce pill burden and may limit side effects tied to higher doses of a single agent. Strengths such as perindopril amlodipine 10 5 and 5 5 support flexible titration.

Ordering from Canada often brings meaningful savings. Typical customers save 60–80 % versus usual US retail pricing, whether choosing the brand name Viacoram or a generic equivalent. If you pay out of pocket, you can purchase perindopril/amlodipine without insurance and still benefit from Canadian pricing.

For current promotions, see our perindopril amlodipine discount opportunities. Multi-month supplies can lower the per-month cost, and we offer discreet, prompt, express shipping.

Side Effects and Safety

• Common: cough, dizziness, headache, flushing, fatigue, nausea, diarrhea or constipation.
• Swelling of ankles or feet (peripheral edema) related to amlodipine.
• Low blood pressure symptoms: lightheadedness, faintness, especially on standing.
• Higher potassium on labs (hyperkalemia), especially with potassium supplements or certain diuretics.
• Skin rash or itching.
• Palpitations or fast heartbeat.

Serious but less common risks include angioedema (swelling of face, lips, tongue, or throat), kidney impairment, significant hypotension, liver enzyme changes, and severe allergic reactions. Do not use if you have a history of angioedema with ACE inhibitors, are pregnant, or plan pregnancy. Use caution with renal artery stenosis, severe aortic stenosis, or dehydration. Seek urgent help for swelling or breathing difficulty.

Onset Time

Blood pressure often begins to improve within the first week. The full effect may take 2–4 weeks as the dose stabilizes. If you switch from monotherapy, allow time for the new combination strength to show steady-state results before judging control. Edema from amlodipine, if it occurs, may appear during the first weeks and can guide dose selection.

Compare With Alternatives

Perindopril alone (for example, perindopril 10mg) lowers blood pressure by reducing angiotensin II. It may be enough for mild hypertension. People needing further control often add another class. The combination simplifies this step into a single tablet.

Amlodipine monotherapy (5–10 mg) relaxes arteries and is effective across many populations. It can cause dose-related ankle edema. Pairing with perindopril may reduce that edema and improve overall pressure reduction compared with increasing amlodipine alone.

Perindopril/indapamide is another fixed-dose option when a diuretic is preferred. Some patients respond better to an ACE inhibitor plus thiazide-like diuretic. Others do well on perindopril amlodipine or even triple therapy such as perindopril indapamide amlodipine selected by a prescriber. The best choice depends on your blood pressure pattern, comorbidities, and tolerance.

Combination Therapy

• With a diuretic (hydrochlorothiazide or indapamide) for additional blood-pressure reduction.
• With a statin to address cardiovascular risk in patients with dyslipidemia.
• With beta-blockers for specific indications such as post-MI or angina, if appropriate.
• Monitor blood pressure and electrolytes when adding agents that can affect potassium or renal function.
• If dizziness or hypotension occurs after adding a new drug, prescribers may adjust doses.

Patient Suitability and Cost-Saving Tips

Perindopril/amlodipine suits adults who need two agents to control hypertension or who benefit from a lower pill count. It may not suit those who are pregnant, have prior ACE inhibitor angioedema, severe aortic stenosis, or significant hypotension. Kidney or liver issues may require closer monitoring and careful dose selection.

Interactions can occur with potassium-sparing diuretics, potassium supplements, ARBs, aliskiren (especially in diabetes or kidney disease), NSAIDs, lithium, or strong CYP3A4 modulators that affect amlodipine levels. Limit high-potassium salt substitutes unless advised.

To manage costs, compare brand and generic options such as Viacoram and apo perindopril amlodipine. Ask your prescriber about strength flexibility, including perindopril arginine amlodipine. Consolidating to a multi-month supply can reduce the per-month expense. You can also view the cash price perindopril amlodipine at checkout, and set gentle reorder reminders so you do not run out.

Strengths vary by region and brand. You may see perindopril amlodipine 10 5, perindopril amlodipine 10 10, and perindopril arginine amlodipine brand name listings. If your prescription specifies a salt form or exact strength, select the matching product during checkout.

Authoritative Sources

Servier Canada Viacoram product page

Health Canada Drug Product Database

FDA labeling database (reference class information)

Order Perindopril/Amlodipine from Youdrugstore: add to cart, upload your prescription, and we ship with prompt, express handling.

This content is for educational purposes and does not replace advice from your healthcare professional. Always follow your prescriber’s directions and the medication guide that comes with your medicine.