Periostat® Tablets for Periodontitis

What Periostat Is and How It Works

Periostat® is a prescription tablet used as adjunct therapy for adult periodontitis. It contains a low dose of doxycycline designed to reduce collagenase activity in the gums. This helps support scaling and root planing performed by your dental professional. We offer US delivery from Canada, making it easier to manage costs without insurance. YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

Doxycycline hyclate 20 mg tablets work by modulating the host response rather than acting as a conventional antibiotic at this dosage. The treatment helps balance enzymes that break down connective tissue. It does not rely on antibacterial effects at the prescribed dose. Your dental team may use it alongside cleanings and local therapies to maintain periodontal health.

Who It’s For

This medicine is indicated as an adjunct to scaling and root planing in adults with chronic Periodontitis. It is not for acute infections. People with a known allergy to tetracyclines should not take it. Children under 8 years and pregnant individuals should avoid tetracyclines due to risks of tooth discoloration and effects on bone development. Those who are breastfeeding should discuss risks and benefits with a prescriber. If you use systemic retinoids such as isotretinoin, inform your clinician due to the risk of increased intracranial pressure.

Photosensitivity can occur with tetracyclines. Limit sun exposure and use protection. Tell your clinician about any history of esophagitis, liver disease, or severe gastrointestinal issues. If you are being monitored for bleeding risks, share your anticoagulant use before starting therapy.

Dosage and Usage

The standard labeled schedule is a low-dose tablet taken twice daily, about 12 hours apart, as an adjunct to dental procedures. Take each dose with a full glass of water to reduce the risk of esophageal irritation. If possible, take it at least one hour before or two hours after meals. Spacing the doses consistently helps maintain steady exposure.

Avoid taking it at the same time as antacids or supplements containing aluminum, calcium, magnesium, or iron. These can bind the medicine and reduce absorption. Stick with the plan set out by your prescriber and dental professional. When uncertain about timing or duration, defer to the official label and your clinician’s guidance.

Strengths and Forms

The brand is supplied as oral tablets. The commonly used strength is Periostat 20 mg tablets. Generic doxycycline low-dose tablets may be available depending on the market.

Availability can vary by region and manufacturer. Your order may be filled by an equivalent strength if your prescription allows substitution. Check the label on your bottle for the exact product dispensed.

Missed Dose and Timing

If you miss a dose, take it when you remember unless it is close to the next dose. If it is almost time for the next dose, skip the missed dose. Do not double up to make up for a missed tablet. Keeping a simple schedule or reminder can reduce missed doses over a long course.

Take the tablet with enough water to avoid throat or esophageal discomfort. Try to remain upright for a short period after taking it. If you feel stomach upset, talk to your clinician or pharmacist about timing strategies consistent with the label.

Storage and Travel Basics

Store tablets in the original container with the lid closed. Keep them at room temperature away from excess moisture and direct light. Do not store in a bathroom. Keep out of reach of children and pets. Do not use tablets that are damaged or past the labeled expiration date.

When traveling, pack your medication in a carry-on with a copy of your prescription. Use a daily reminder or travel pill organizer if that suits your routine. Avoid mixing tablets from different bottles. If crossing borders, carry documentation to smooth screening. Check local regulations before travel to ensure uninterrupted use.

Benefits

This therapy supports periodontal treatment plans by reducing elevated enzymes that break down gum tissue. It helps your dental professional maintain improvements achieved with scaling and root planing. The oral tablet form offers consistent dosing without local procedures at every visit. It can be used alongside antimicrobial rinses or local therapies as directed.

Because the dose is subantimicrobial, it aims to minimize effects on normal flora when used as labeled. This makes the treatment a host-modulation option rather than a standard antibiotic course. Your dentist may monitor gum measurements and symptoms over time to assess benefit.

Side Effects and Safety

• Common: nausea, stomach upset, diarrhea, headache
• Possible: photosensitivity, mild skin rash, oral or vaginal candidiasis
• Less common: esophagitis or esophageal irritation, dizziness

Serious but rare risks include severe allergic reactions, intracranial hypertension, and Clostridioides difficile-associated diarrhea. Stop the medicine and seek care if you develop signs of hypersensitivity, persistent severe headache with vision changes, or significant, persistent diarrhea. Tetracyclines can affect developing teeth and bones; avoid use during pregnancy, in nursing without prescriber advice, or in children under 8.

Drug Interactions and Cautions

Tell your clinician and pharmacist about all medicines and supplements you take. Antacids, calcium, magnesium, iron, and bismuth can reduce absorption; separate these from your dose. Warfarin and related anticoagulants may require closer monitoring. Tetracyclines can reduce the effectiveness of some oral contraceptives; consider a backup method.

Avoid combining with isotretinoin or other systemic retinoids due to the risk of increased intracranial pressure. Barbiturates and some seizure medicines may lower tetracycline levels. Do not take simultaneously with penicillin-class antibiotics as they may antagonize each other. Alcohol use can complicate adherence and stomach tolerance; discuss your habits with your prescriber.

What to Expect Over Time

This medicine is intended for long-term adjunct use alongside professional dental care. Your dentist may evaluate gum pocket depth, bleeding on probing, and other measures at routine visits. Some people notice easier maintenance of gum health when they follow the schedule and oral hygiene plan recommended by their dental team.

Consistency matters. Keep regular dental appointments and brush and floss as directed. If you experience sensitivity to sunlight, adjust outdoor exposure and use protection. For broader reading on medication routines and symptom tracking, see our article Claritin Allergy Medicine.

Compare With Alternatives

Adjunct options for periodontal care include locally applied therapies such as doxycycline gels or minocycline microspheres placed by a dental professional. Antiseptic rinses like chlorhexidine may also be used as directed. Systemic host-modulation with low-dose doxycycline is one approach among several.

For broader oral care topics and maintenance tools, explore the Oral Health category and our condition overview for Periodontitis. For general dermatology care reading, you can also visit Metrogel For Rosacea for insights on using topical therapies, and Tadalafil Vs Sildenafil for a comparative guide in another category.

Pricing and Access

We aim to keep the Periostat 20 mg price transparent on the product page. You can also compare the Doxycycline hyclate 20 mg price if your prescriber allows generic substitution. Orders include US shipping from Canada so you can plan your refill cadence accordingly. For seasonal offers, see our site Promotions page.

Many patients pay out of pocket. We display clear pricing and support secure, encrypted checkout. If you need help reviewing options, contact our customer care team before placing your order.

Availability and Substitutions

Supply can vary. If brand stock is limited, your prescriber may consider a therapeutically equivalent generic. Ask about Periostat generic 20 mg when appropriate for your treatment plan. Your pharmacy team will follow your prescription and local substitution rules.

If an item is unavailable, your clinician might recommend a different periodontal adjunct or a local therapy. We continue to add oral health options; check the Oral Health section for updates.

Patient Suitability and Cost-Saving Tips

This treatment may suit adults with chronic periodontal disease who complete professional scaling and root planing and need adjunct support. It is not right for those with tetracycline allergy, children under 8, pregnancy, or some breastfeeding situations. People with significant liver disease or a history of severe esophagitis should discuss risks with a prescriber.

To manage expenses, consider multi-month fills if approved on your prescription. This can reduce per-fill fees and help you stay on schedule. If you track spending, compare the Periostat 20 mg cash price with the generic listing when available. Set refill reminders so you do not run short during a long course.

We carry treatments for many conditions. For example, see Pravastatin Sodium for cholesterol management and Zopiclone for short-term sleep support. Browse categories to find everything you need in one place.

Questions to Ask Your Clinician

• Role in my plan: how this adjunct supports scaling and root planing
• Expected duration: how long I should continue therapy
• Sun sensitivity: ways to reduce risk outdoors
• Interactions: how to separate doses from minerals and supplements
• Monitoring: what signs my dentist will track over time
• Alternatives: when local therapies or rinses might be better

Authoritative Sources

FDA DailyMed

Health Canada Drug Product Database

FDA Drugs

Ready to proceed? Order doxycycline 20 mg online with express, temperature-controlled handling when required. Ships from Canada to US. Prescription required; always follow your prescriber’s directions.

Disclaimer: This page provides general information and does not replace medical advice. Always check the official label and consult your healthcare professional.