Qulipta® (atogepant) Tablets for Preventive Migraine Treatment

What Qulipta® Is and How It Works

Qulipta (atogepant) is an oral calcitonin gene-related peptide (CGRP) receptor antagonist. It is taken once daily to help prevent migraine in adults. It blocks CGRP receptor activity that drives migraine pathways. This reduces the frequency of monthly migraine days over time. Common strengths include 10 mg, 30 mg, and 60 mg tablets.

YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba, and prescriptions are reviewed by licensed pharmacists before dispensing. Our pharmacy serves US patients at Canadian prices.

We source through licensed, vetted international partner pharmacies to supply authentic brand medicines, a broad selection, and affordable pricing.

Qulipta 60 mg is often used for chronic migraine prevention. For episodic migraine, approved options include 10 mg, 30 mg, or 60 mg once daily. This page explains qulipta uses, qulipta dosage details, and how qulipta 60mg tablets fit into long-term care.

Dosage and Usage

• Episodic migraine prevention: 10 mg, 30 mg, or 60 mg taken once daily.
• Chronic migraine prevention: 60 mg taken once daily.
• Can be taken with or without food. Swallow tablets whole.
• Best time to take Qulipta: choose a consistent time each day. Morning or evening is acceptable.
• Missed dose: take when remembered. If the next dose is due soon, skip the missed dose. Do not double doses.
• Drug interactions: strong CYP3A4 inhibitors or OATP inhibitors may require 10 mg once daily. Strong or moderate CYP3A4 inducers may require 30 mg or 60 mg once daily.
• Renal impairment: for severe renal impairment or end-stage renal disease, use 10 mg once daily for episodic migraine; avoid use for chronic migraine.
• Hepatic impairment: avoid in severe hepatic impairment; no adjustment is generally needed in mild to moderate impairment.
• Other guidance: see qulipta prescribing information for complete interaction tables and adjustments.

• Storage: store at 20–25 °C (68–77 °F) in the original container. Protect from moisture and light.
• Keep tablets in a dry place. Do not store in a bathroom.
• Keep out of reach of children and pets.
• Travel: pack your tablets in carry-on luggage. Keep the label visible for TSA. Bring enough tablets for the full trip, plus extra.
• Do not leave medicine in a hot car. Use a small pill organizer if needed, and keep the original label in your bag.
• If flying across time zones, adjust to the new local time and take once daily.

Benefits and Savings

Qulipta reduces the number of monthly migraine days in many adults. It is taken as a small tablet and needs no injections, refrigeration, or device training. Flexible dosing allows 10 mg, 30 mg, or 60 mg once daily, tailored to preventive needs. Many patients notice fewer headaches within the first month, with gains building by week 12.

Cost matters for long-term preventive therapy. At YouDrugstore, the qulipta price reflects Canadian pharmacy pricing. Many US patients see 60–80% savings compared with typical US prices. Check qulipta cost by strength, including qulipta 60 mg cost and qulipta 30 mg options. Multi-month supplies can lower per-month costs, and bulk promotions may apply to some sizes.

For extra value, see current qulipta coupon offers on our Promotions page.

Simple reorders help keep therapy consistent. You can set a reminder in your account so you never run short. Prompt, express shipping serves all US states where permitted.

Side Effects and Safety

• Constipation
• Nausea or upset stomach
• Fatigue or tiredness (qulipta fatigue)
• Decreased appetite
• Weight loss (usually small)
• Indigestion or abdominal discomfort
• Dizziness
• Abnormal liver tests (generally infrequent)

Serious effects are uncommon but can include severe constipation, allergic reactions (rash, swelling, difficulty breathing), and significant liver issues. Avoid use in severe hepatic impairment. Dose changes may be needed with certain interacting medicines. Discuss pregnancy, plans to conceive, or breastfeeding with a clinician. Avoid driving or hazardous tasks if drowsy. For a full list of side effects of qulipta, review the official materials below.

Onset Time

Qulipta begins working quickly for many adults. Some notice fewer migraine days within the first week. Results typically build over 4 weeks. Maximum benefit is often seen by 8–12 weeks as the dose is maintained and adherence stays consistent. Continue daily dosing to sustain prevention. Discuss any persistent side effects or lack of efficacy with a healthcare professional.

Compare With Alternatives

Topiramate is a long-standing oral preventive option. It can help reduce monthly migraine days but may cause paresthesias, cognitive effects, or weight loss in some patients. See Topiramate for details on strengths and pricing. Qulipta offers a targeted CGRP mechanism without injections, which some adults prefer.

Acute gepants treat attacks when they occur. Ubrelvy® (ubrogepant) is taken at the onset of a migraine and is not a preventive. Many patients on Qulipta still keep an acute medicine on hand.

Triptans (such as sumatriptan) and nonsteroidal anti-inflammatory drugs remain common acute options. Injectable CGRP monoclonal antibodies (erenumab, galcanezumab, fremanezumab) are preventive alternatives given monthly or quarterly. Choice depends on response, side effects, comorbidities, and convenience.

Combination Therapy

• Qulipta for prevention plus a triptan or NSAID for acute migraine attacks.
• Qulipta plus a gepant for acute use (for example, ubrogepant) may be used when advised by a clinician.
• Qulipta with onabotulinumtoxinA (Botox) is considered in chronic migraine for some adults.
• Avoid duplicate CGRP preventives unless a clinician directs otherwise.
• Review all medicines for CYP3A4 or OATP interactions before starting or changing doses.

Patient Suitability and Cost-Saving Tips

Qulipta is intended for adults who need preventive migraine treatment. It can suit those who have not tolerated, or not responded to, other preventives. It may be considered when a non-injectable option is preferred.

It may not be appropriate in severe hepatic impairment or in severe renal impairment for chronic migraine dosing. Caution is needed in those with a history of severe constipation. Discuss use in pregnancy or while breastfeeding. Review all drugs and supplements for interactions.

There is no qulipta generic currently available. If cost of qulipta is a concern, consider a 90-day supply to reduce the monthly price. Watch for site promotions that lower qulipta cost. You can turn on reorder reminders in your account so you refill on time. If side effects limit use, ask about dose adjustments such as 10 mg or 30 mg options.

Authoritative Sources

US Prescribing Information (AbbVie)

FDA Label and Medication Guide

Qulipta Consumer Site

Order Qulipta® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express shipping.

This information is educational and does not replace advice from your healthcare professional. Always follow your prescriber’s directions and the product labeling.