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Retevmo

Cancer

Please note: a valid prescription is required for all prescription medication.

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Price:

Price range: $5,148.99 through $10,276.99

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Retevmo is a targeted therapy used to treat cancers that have specific genetic alterations in the RET gene. It is approved for certain types of non-small cell lung cancer (NSCLC), thyroid cancer, and medullary thyroid cancer. By blocking abnormal RET signals, Retevmo helps slow or stop the growth of cancer cells.

Benefits

  • Specifically targets RET gene alterations found in some cancers.
  • Helps reduce tumor size and delay cancer progression.
  • Can be used in both adult and pediatric patients (12 years and older).
  • Oral treatment option that can be taken at home.
  • Often better tolerated than traditional chemotherapy.

Dosage

  • The typical adult dose is 120 mg or 160 mg twice daily, depending on body weight.
  • Doses are taken approximately 12 hours apart, with or without food.
  • Tablets should be swallowed whole — do not crush or chew.
  • Dose may be adjusted based on side effects or lab test results.

Warnings and Precautions

  • May affect liver function — regular liver tests are recommended.
  • Can prolong the QT interval, increasing the risk of heart rhythm problems.
  • Risk of high blood pressure — blood pressure should be monitored.
  • May cause bleeding or allergic reactions in rare cases.
  • Use with caution in patients with existing liver, kidney, or heart conditions.
  • Avoid during pregnancy and breastfeeding.

Usage Instructions

  • Take Retevmo twice daily, about 12 hours apart.
  • Can be taken with or without food, but always consistently.
  • Swallow tablets whole with a glass of water.
  • If a dose is missed and it’s less than 6 hours from the next dose, skip it. Do not take two doses at once.
  • Keep up with regular doctor appointments and blood tests to monitor response and side effects.

Storage Information

  • Store at room temperature (20°C to 25°C).
  • Keep the medication in its original container.
  • Protect from moisture and light.
  • Keep out of reach of children.

Common Side Effects

  • Mild to moderate effects: dry mouth, diarrhea, high blood pressure, constipation, swelling, fatigue, or rash.
  • Serious (seek medical attention): liver problems (such as yellowing of the skin or dark urine), bleeding, severe abdominal pain, chest pain, or signs of heart rhythm changes.

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