Risperdal Consta® Long-Acting Injection Kit for Maintenance Treatment

What Risperdal Consta® Is and How It Works

Risperdal Consta® is a long-acting injectable form of risperidone. It helps manage schizophrenia and maintain stability in bipolar I disorder. The kit contains risperidone microspheres and a diluent for intramuscular injection. Injections are given every two weeks by a healthcare professional. If you need Risperdal Consta Kit without insurance, you can still order it at Canadian pricing through our service.

YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba, and prescriptions are reviewed by licensed pharmacists before dispensing.

Risperidone is an atypical antipsychotic. It blocks dopamine D2 and serotonin 5-HT2A receptors. This balance helps reduce positive and negative symptoms. The microspheres release risperidone slowly over time. After the first injection, oral risperidone is usually continued for three weeks to maintain levels. Dose adjustments are individualized based on response and tolerability.

Common dosing strengths include 25 mg, 37.5 mg, and 50 mg every two weeks. Deltoid or gluteal muscles are suitable sites. Steady state is reached after several injections. The supplied kit supports proper reconstitution and delivery.

Dosage and Usage

• Initiation: Oral risperidone is typically used first to confirm tolerability.
• Transition to long-acting: Give the first injection while continuing oral risperidone for about three weeks.
• Maintenance: Injections are scheduled every two weeks at a dose set by the prescriber.
• Sites: Inject intramuscularly into the deltoid or gluteal muscle; rotate sites each time.
• Reconstitution: Use the provided diluent and vial adapter. Reconstitute only when ready to inject.
• Technique highlights: Create a uniform suspension by vigorous mixing. Inject at 90 degrees into muscle. Do not administer intravenously.
• After preparation: Use the suspension promptly. Do not store the reconstituted product.
• Missed dose: The next injection is usually given as soon as possible. Longer gaps may require oral coverage or re-initiation per prescriber guidance.

• Store the kit in a refrigerator at 2–8 °C (36–46 °F). Do not freeze.
• You may keep an unopened kit at room temperature (up to 25 °C/77 °F) for up to 7 days before use. Do not return it to the refrigerator after this period.
• Keep the kit in the original carton to protect from light.
• For travel, use an insulated container with cold packs. Avoid direct contact with ice and do not freeze.
• Do not reconstitute until the appointment. Keep out of reach of children.
• We ship with prompt, express, cold-chain shipping to protect temperature-sensitive medicines.

Benefits and Savings

Risperdal Consta® helps maintain steady symptom control with a twice-monthly schedule. It supports adherence by removing the need for daily pills. Many people notice fewer peaks and troughs compared to some oral regimens. The kit is designed to simplify preparation for the injecting clinician.

Ordering through our Canadian pharmacy can reduce the Risperdal Consta Kit cost. Typical savings are 60–80% compared to usual U.S. pricing. Multi-month supplies can lower the per-month price, and you can set gentle reorder reminders in your account. You can still save on Risperdal Consta Kit even without insurance.

We work with licensed, vetted international partner pharmacies to offer authentic brand medications, a wide selection, and competitive pricing.

For current offers, see our Risperdal Consta Kit coupon page.

Side Effects and Safety

• Injection site pain, redness, or swelling
• Drowsiness or fatigue
• Dizziness or lightheadedness
• Weight gain or increased appetite
• Extrapyramidal symptoms (tremor, rigidity, akathisia)
• Anxiety or restlessness
• Nausea, constipation, or dry mouth
• Increased prolactin (e.g., menstrual changes, breast symptoms)
• Headache or insomnia

Serious but less common risks include neuroleptic malignant syndrome, tardive dyskinesia, high blood sugar, seizures, leukopenia/neutropenia, orthostatic hypotension, and QT prolongation. Antipsychotics increase mortality in elderly patients with dementia-related psychosis; Risperdal Consta® is not approved for this use. Discuss stroke risk in older adults, allergy history, pregnancy or breastfeeding, and all medicines and supplements you take.

Onset Time

Oral risperidone is usually continued for about three weeks after the first injection. This covers the time before the depot fully releases medication. Some symptom improvements may appear within a few weeks, especially with oral overlap. Steady blood levels are reached after several injections, often around 6–8 weeks. Individual responses differ based on dose and clinical factors.

Compare With Alternatives

Invega Sustenna (paliperidone palmitate) is a monthly injection, with a two-dose initiation in week 1 and week 2. It offers a longer interval than a two-week schedule. Paliperidone is the active metabolite of risperidone, and some patients tolerate it differently.

Abilify Maintena (aripiprazole monohydrate) is a monthly option with partial dopamine agonist activity. It may have a different side-effect profile, with a lower risk of elevated prolactin but a risk of akathisia for some.

Haloperidol decanoate is a first-generation antipsychotic depot given monthly or every four weeks. It can control symptoms but has a higher risk of extrapyramidal effects for many people. Choice among long-acting injectables depends on prior response, tolerability, dosing interval preferences, and clinical history.

Combination Therapy

• With mood stabilizers: May be combined with lithium or valproate for bipolar I maintenance.
• With oral risperidone: Continued during initiation and sometimes after missed injections per clinical guidance.
• With anticholinergics: Agents like benztropine may be used short term for extrapyramidal symptoms.
• Drug interactions: Strong CYP2D6 inhibitors (e.g., fluoxetine, paroxetine) can increase exposure; enzyme inducers (e.g., carbamazepine) can reduce levels.
• Other CNS depressants: Additive sedation may occur with benzodiazepines or alcohol; caution is advised.
• Antihypertensives: Additive blood pressure lowering can happen; monitoring is recommended.

Patient Suitability and Cost-Saving Tips

Candidates often include adults with schizophrenia or bipolar I disorder who need consistent maintenance treatment and prefer a long-acting option. Prior tolerability to oral risperidone is commonly established before switching. People who benefit from supervised dosing or struggle with daily pills may prefer this schedule.

Those who may not be suitable include patients with known hypersensitivity to risperidone, a history of neuroleptic malignant syndrome, or uncontrolled seizures. Use caution in Parkinson’s disease, Lewy body dementia, significant orthostatic hypotension, or with a history of prolonged QT. The product is not approved for dementia-related psychosis. Renal or hepatic impairment may require lower doses.

Pregnancy and breastfeeding require a careful risk–benefit discussion with the prescriber. Elevated prolactin can impact fertility and bone health with long-term use. Report movement symptoms, severe sedation, or signs of high blood sugar promptly.

To manage the Risperdal Consta Kit price, consider ordering multiple months at once when appropriate. This can reduce the per-month cost and the number of shipments. You can enable reorder reminders in your account so you do not run out between clinic visits. Availability of a generic Risperdal Consta Kit varies by market; brand may be dispensed when a true generic is not available. If you are purchasing without insurance, many patients still see meaningful savings compared with typical U.S. prices.

Authoritative Sources

Janssen Risperdal Consta Full Prescribing Information (U.S.)

Janssen Canada Product Monograph: Risperdal Consta

FDA Label and Medication Guide Archive

Order Risperdal Consta® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This content is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment. Always speak with a qualified healthcare professional about your specific situation.