Salofalk® Rectal Suspension for Ulcerative Colitis Relief

What Salofalk® Is and How It Works

Salofalk® Suspension is a rectal mesalamine (5-aminosalicylic acid) enema used to treat mild to moderate distal ulcerative colitis, including proctitis and proctosigmoiditis. Each Salofalk rectal suspension 4g 60ml bottle delivers anti-inflammatory action directly to the inflamed rectum and sigmoid colon. Many people buy Salofalk Suspension online to access Canadian pricing and dependable supply. You can also request the Salofalk Suspension price for cash orders or Salofalk Suspension without insurance.

Mesalamine works topically in the colon lining. It reduces local inflammatory mediators and helps calm symptoms like urgency, bleeding, and cramps. Rectal delivery limits systemic exposure and targets the area where flares occur. Dosing is typically once nightly during active disease, then less often for maintenance, as directed by a prescriber.

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Dosage and Usage

• Typical induction: one 4 g/60 mL enema at bedtime daily for 3 to 6 weeks, or as prescribed.
• Maintenance may involve less frequent dosing (for example, every 2 to 3 days) per prescriber guidance.
• Warm the unit to room temperature if cool. Shake the bottle well for at least 30 seconds to ensure a uniform suspension.
• Remove the cap. If needed, lubricate the applicator tip with a small amount of water-based lubricant.
• Lie on the left side with the left leg straight and right knee bent. Gently insert the applicator tip into the rectum.
• Squeeze the bottle steadily until it is empty. Withdraw while still compressing the bottle to prevent backflow.
• Remain lying on the left side for 30 minutes, then retain the enema as long as possible, ideally overnight.
• Each bottle delivers a single dose. Discard after use.
• Missed dose: use when remembered the same night. If the next dose is due soon, skip the missed dose and resume the regular schedule. Do not double.

• Storage: store at 15–25 °C (59–77 °F). Do not freeze. Protect from light and keep in the carton until use.
• Keep bottles upright and cap closed until administration.
• Travel: pack upright in a protective pouch. Avoid heat over 30 °C (86 °F) and keep away from freezing.
• Do not use if the suspension has separated into clumps or the bottle is damaged.
• Keep out of reach of children and pets.

Benefits and Savings

Rectal mesalamine delivers medicine where it is needed most. Many patients experience reduced rectal bleeding and urgency within the first one to two weeks. Nightly dosing simplifies routines during a flare, and once symptoms stabilize, dosing may scale down for maintenance under medical supervision. Evidence supports the efficacy of Salofalk Suspension in distal disease and proctosigmoiditis, including improved mucosal healing rates compared with no topical therapy.

Ordering from Canada often lowers the Salofalk Suspension cost. Savings of 60–80% versus typical US prices are common, especially for ongoing therapy. This can help when budgeting for Salofalk Suspension without insurance or when tracking out-of-pocket expenses. Per-month costs may drop further with multi-month supplies or bulk promotions.

Salofalk Suspension coupon availability may vary; check promotions periodically for current deals.

Side Effects and Safety

• Common: abdominal cramping, rectal discomfort, gas, nausea, headache.
• Rectal symptoms: fullness, mild urgency, or minor leakage shortly after dosing.
• Skin: mild rash or itching.
• General: fatigue or dizziness in some users.

Serious but uncommon reactions can include mesalamine intolerance (worsening cramps, bloody diarrhea, fever), pancreatitis, liver enzyme elevations, interstitial nephritis, blood count changes, myocarditis or pericarditis, and severe allergic reactions. Patients with salicylate allergy, significant kidney or liver disease, or a history of mesalamine intolerance should discuss risks with a clinician. Periodic kidney function monitoring is often recommended during mesalamine therapy.

Onset Time

Symptom relief often begins within 3 to 7 days of nightly use. Bleeding and urgency may continue to improve over 2 to 4 weeks as the dose is maintained. Endoscopic healing in proctitis or proctosigmoiditis may take several weeks. After induction, some patients transition to maintenance dosing to help sustain remission and reduce relapse frequency.

Compare With Alternatives

For disease limited to the rectum, a suppository can be convenient. Salofalk® Suppositories deliver mesalamine directly to the rectal mucosa, which may suit very distal disease with minimal sigmoid involvement. For broader coverage of the rectum and sigmoid colon, a suspension enema often provides greater reach.

Another mesalamine enema option is Pentasa® Enema. Formulation differences and bottle design can affect handling preferences, while the active ingredient is the same class. Prescribers may select either based on tolerance, cost, and availability.

Oral mesalamine tablets can help when inflammation extends beyond the reach of rectal therapy. Many clinicians combine oral and rectal mesalamine for enhanced efficacy during active flares, then tailor maintenance to disease extent and patient preference.

Combination Therapy

• Oral mesalamine plus rectal mesalamine during induction for left-sided disease.
• Rectal mesalamine with a short course of rectal corticosteroids if symptoms persist.
• Adjunct to systemic therapies (biologics or immunomodulators) in recurrent distal flares.
• Dose adjustments and tapering are individualized to balance control and tolerability.

Patient Suitability and Cost-Saving Tips

Salofalk Suspension is used for adults with mild to moderate distal ulcerative colitis. It is not designed for Crohn’s disease or extensive colitis that requires systemic therapy alone. People with severe renal or hepatic impairment, salicylate hypersensitivity, or prior mesalamine-induced intolerance may not be good candidates. Pregnant or breastfeeding patients should review risks and benefits with their healthcare professional.

Cost planning matters for long-term care. The Salofalk Suspension cost varies by supply size and market conditions. You can order Salofalk Suspension and track spending month to month, with optional reminders to reorder before your supply runs low. Multi-month purchases can reduce the per-month cost, and periodic bulk promotions may add further savings. These strategies can help when paying the Salofalk Suspension cash price.

Ordering is simple. Add the product to your cart, upload a valid prescription, and select delivery options. You receive prompt, express, cold-chain shipping with careful packaging. Customer-service chat is available during posted hours for order support.

Authoritative Sources

Dr. Falk Pharma Salofalk information (mesalamine)

Health Canada Drug Product Database: mesalamine rectal products

FDA prescribing information for mesalamine rectal suspension (class reference)

Order Salofalk® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This material is educational and does not replace advice from your healthcare professional. Always follow the guidance of your prescriber and the product insert.