Skyrizi® Pre-fill Cartridge w/ Injector for Crohn’s Disease and Ulcerative Colitis

This pre-filled cartridge with an on-body injector delivers a biologic for Crohn’s disease and ulcerative colitis. It helps maintain control after an IV induction phase. We provide US delivery from Canada and clear options for paying without insurance.

What Skyrizi Is and How It Works

Skyrizi® contains risankizumab, a selective inhibitor of the p19 subunit of interleukin‑23 (IL‑23). By targeting IL‑23, this treatment helps calm overactive immune pathways linked to intestinal inflammation. The on-body injector is designed to deliver a full maintenance dose subcutaneously at scheduled intervals determined by the approved label.

YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

This medicine is approved for adults with moderate to severe Crohn’s disease and ulcerative colitis. It is also authorized for plaque psoriasis and psoriatic arthritis, though different strengths and devices may be used for those conditions. Always follow the official label and your prescriber’s guidance.

Who It’s For

This therapy is intended for adults who have been diagnosed with moderate to severe Crohn’s disease or ulcerative colitis and are appropriate candidates for IL‑23 inhibition. It may be started after an IV induction phase and then continued as a maintenance plan using the cartridge and injector.

Patients with active, serious infections should not start until the infection is controlled. Screening for tuberculosis is recommended before initiation. Those with a history of hypersensitivity to risankizumab or any component should avoid this treatment. The class may also be used in plaque psoriasis and psoriatic arthritis; see related information in Plaque Psoriasis and Psoriatic Arthritis.

Dosage and Usage

After completing induction as directed on the label, maintenance dosing transitions to subcutaneous administration with the on-body injector. When indicated, the on-body device delivers a full maintenance amount at the scheduled interval. The exact schedule is determined by the approved indications and your prescriber.

If your plan includes the on-body device, it is generally applied to clean, intact skin on the abdomen away from the navel. Allow the carton to reach room temperature out of the refrigerator before use, as specified in the instructions for use. The Skyrizi on-body injector 360 mg cartridge phrase refers to the maintenance presentation used for Crohn’s disease and ulcerative colitis in many adults; follow the official dosing schedule on the product label.

Do not change your dose or timing without speaking to your healthcare professional. Refer to the instructions for use included in the package for step-by-step preparation, placement, and completion details.

Strengths and Forms

This product is supplied as a pre-filled cartridge used with an on-body injector. A commonly published maintenance presentation is 360 mg/2.4 mL for subcutaneous use following induction for Crohn’s disease or ulcerative colitis. Availability may vary by country and by manufacturer supply.

Other presentations exist for different indications, such as prefilled syringes or pens used for dermatologic conditions. Refer to the label for the appropriate device and strength for your condition.

Missed Dose and Timing

If a maintenance dose is missed, administer it as soon as remembered and then resume the regular schedule. If the next dose is already near, ask your prescriber or pharmacist which timing is best. Do not double the dose to make up for a missed administration. Keeping a reminder system can help maintain the planned interval.

Storage and Travel Basics

Store the carton in a refrigerator in the original packaging to protect from light. Do not freeze or shake. If traveling, keep the carton insulated and avoid temperature extremes. When ready to use, allow it to reach room temperature out of the refrigerator as directed in the instructions for use. Keep out of reach of children and pets.

When flying, carry it in a hand-luggage cooler with your prescription label and a travel letter if available. Security rules can vary, so arrive early and keep the carton and accessories together. Dispose of used components in a sharps container; do not place them in household trash.

Pen Handling and Sharps Disposal

Although this product uses an on-body injector rather than a traditional prefilled pen, many handling principles are similar:

• Check carton and device: verify the carton, cartridge, and injector are intact and within expiry.
• Skin prep: choose a flat area on the abdomen away from the navel; cleanse and dry.
• Attach and arm: load the cartridge into the injector as directed by the instructions for use.
• Apply and start: place the device on the skin, press to start, and wait until completion indicator confirms delivery.
• Removal: after completion, gently remove the device and check the site.
• Disposal: place the used injector and cartridge into an approved sharps container.

Never reuse devices or needles. If a device fails to start or stops early, follow the instructions for use and contact your prescriber or pharmacist for next steps.

Benefits

This treatment offers scheduled maintenance dosing after induction, which can simplify ongoing care. The on-body injector automates delivery, reducing the need for manual injection technique. For many adults, consistent maintenance can help reduce flares and support symptom control over time.

Side Effects and Safety

Common side effects can include:

• Upper respiratory infections
• Headache or fatigue
• Injection site reactions
• Fungal skin infections

Serious or rare risks may include hypersensitivity reactions, serious infections, and reactivation of tuberculosis. Report fever, persistent cough, shortness of breath, or signs of severe allergic reaction such as swelling or hives. People using insulin or sulfonylureas are not specifically affected by this class, but hypoglycemia risk should always be monitored for those medicines separately.

Live vaccines are generally avoided during treatment; discuss vaccination plans with your clinician before starting and during therapy.

Drug Interactions and Cautions

Risankizumab is an immunomodulator. Concomitant use with other biologics that impact the immune system is typically not recommended unless directed by a specialist. Avoid live vaccines during treatment. Before starting, inform your prescriber about current medicines, recent or chronic infections, and any prior tuberculosis screening results. Alcohol does not have a known direct interaction with this class, but overall liver health and comorbid conditions should be considered.

What to Expect Over Time

People often begin with an IV induction phase under clinical supervision. Maintenance doses with the injector follow a planned schedule. Responses vary; some may observe gradual symptom improvement and steadier periods between flares when doses are taken as scheduled. Using reminders, aligning doses with a calendar date, and keeping supplies organized can support adherence.

Compare With Alternatives

Other biologic options for similar conditions include ustekinumab and adalimumab. For example, Stelara Prefilled Syring targets IL‑12/23 and is used across multiple immune-mediated diseases. Humira targets TNF‑alpha and has broad indications in gastroenterology and rheumatology. Each therapy has distinct dosing, devices, and monitoring needs. Discuss options with your prescriber to choose the best fit for your clinical history.

Pricing and Access

We offer transparent Canadian pricing for the maintenance cartridge. Use the product page to compare options and see availability. You can order risankizumab cartridge online after your prescriber sends a valid script. Many patients look for the Skyrizi cartridge cost without insurance; self-pay amounts vary based on supply and dispensing. For coupon updates and seasonal offers, see our Promotions. Ships from Canada to US with clear tracking.

Availability and Substitutions

Supply can vary by strength and device. If an item is unavailable, a prescriber may recommend a comparable alternative in the same class or a different mechanism of action. Ask your clinician before substituting. For current maintenance presentations and timing, check the label and our product page. You can also look up the risankizumab on-body injector price to compare options across available devices. One micro cue for peace of mind: prescription required and verified.

Patient Suitability and Cost-Saving Tips

Suitable candidates are adults who have completed induction and are continuing maintenance with an IL‑23 inhibitor, have no active serious infection, and have been screened for TB. Those with prior severe hypersensitivity to any component should avoid this therapy.

Cost tips:

• Multi-month supply: discuss larger fills to reduce per-fill fees.
• Refill reminders: set calendar alerts to avoid gaps.
• Self-pay planning: check the Skyrizi cartridge cash price and ask your prescriber about timing visits to align with coverage or assistance windows.
• Canadian pricing: compare options and consider pay out of pocket vs. plan benefits.

For broader reading on treatment families, see Arthritis Drugs and community updates such as World Psoriasis Day. For related conditions in skin, browse our Dermatology category.

Questions to Ask Your Clinician

• Is an IL‑23 inhibitor appropriate for my disease history and goals?
• What induction plan and maintenance interval does the label recommend for me?
• How should I handle missed doses or device issues?
• Which vaccines should be updated before starting?
• What infection signs should lead me to contact the clinic?
• Can multi-month fills reduce overall costs for my situation?

Authoritative Sources

FDA Prescribing Information

Health Canada Drug Product Database

Manufacturer Site

Order from YouDrugstore with prompt, express, cold-chain shipping and US shipping from Canada. This content is educational and not a substitute for professional medical advice.