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Aldactazide® Tablets for Hypertension and Edema
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Spironolactone HCTZ is a prescription combination diuretic for blood pressure and fluid buildup. It joins spironolactone with hydrochlorothiazide in one tablet. You can access Canadian pharmacy value with US shipping from Canada, even if you are comparing options without insurance.
What Aldactazide® Is and How It Works
This medicine combines two well-known diuretics. Spironolactone helps block aldosterone, which reduces sodium and water retention while conserving potassium. Hydrochlorothiazide increases salt and water excretion in the kidneys. Together, the treatment helps lower blood pressure and lessen swelling from extra fluid.
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
Aldactazide tablets pair complementary actions. It may support blood pressure control and reduce edema from conditions like heart failure or liver disease. The combination can offset potassium loss from thiazides, though blood tests are still important.
Who It’s For
This therapy is used for adults with high blood pressure and for edema due to heart failure, cirrhosis, or certain kidney conditions. Spironolactone HCTZ tablets may be considered when a single diuretic is not enough or when potassium balance is a concern.
People with anuria, severe kidney impairment, Addison’s disease, or high potassium should avoid it. Those with sulfonamide allergies may react to hydrochlorothiazide. Discuss pregnancy, breastfeeding, and any endocrine conditions with your clinician before starting.
Dosage and Usage
The dosing schedule is set by your prescriber based on your condition and lab results. Many adults take it once daily, sometimes twice daily. Take tablets with food if stomach upset occurs. Follow the exact directions on your label and do not change your schedule without guidance.
Some patients start on Spironolactone Hydrochlorothiazide 25/25 mg and adjust only under medical supervision. Keep consistent timing each day. Avoid potassium supplements or salt substitutes unless your prescriber specifically approves them.
For general heart health strategies alongside medicines, see our Hypertension Tips.
Strengths and Forms
This treatment is available as oral tablets. Commonly published strengths include Spironolactone/Hydrochlorothiazide 25-25 mg and, in some markets, 50-50 mg. Packaging and makers can vary by country and supplier. The exact strength available may change based on supply.
Missed Dose and Timing
If you miss a dose, take it when you remember unless it is close to your next dose. If it is nearly time, skip the missed tablet and resume your regular schedule. Do not take two doses at once. Because this is a diuretic, many people prefer morning dosing to reduce nighttime urination; confirm your plan with your prescriber.
Storage and Travel Basics
Store tablets at room temperature away from moisture and light, and keep them in the original container with the label. Keep out of reach of children and pets. When traveling, pack your medicine in a carry-on, bring your prescription information, and use a simple pill organizer if helpful. A copy of your current prescription or a recent pharmacy receipt can smooth security checks.
Benefits
This combination provides two diuretic actions in one daily tablet. It can lessen fluid-related swelling and support blood pressure control. Using a single pill may simplify routines compared to taking separate products. In some people, the potassium-sparing component may reduce the need for additional supplements, though monitoring remains important.
Generic Aldactazide offers an established option when a prescriber recommends a combination diuretic. It can fit into broader cardiovascular plans that may also include diet, activity, and other prescribed therapies.
Explore related conditions and options in our Hypertension and Edema sections, or browse the wider Cardiovascular category.
Side Effects and Safety
- More frequent urination
- Dizziness or lightheadedness
- Headache
- Nausea or stomach cramps
- Breast tenderness or menstrual changes
- Rash or photosensitivity
Serious effects can include high potassium, low sodium, severe dehydration, kidney problems, or significant drops in blood pressure. Spironolactone may cause breast changes in some men. Call your healthcare professional right away if you notice muscle weakness, irregular heartbeat, severe vomiting, confusion, or decreased urine output. Report any severe skin reaction immediately.
Drug Interactions and Cautions
Tell your prescriber about all medicines and supplements you take. ACE inhibitors, ARBs, or other potassium-sparing agents can raise potassium when combined with this therapy. Potassium supplements and salt substitutes may also increase risk. NSAIDs may blunt diuretic effect and stress kidneys. Lithium levels can rise with diuretics and require careful monitoring. Alcohol can intensify dizziness or low blood pressure.
Review the full interaction list with a healthcare professional and consider our overview on interactions here: Top Interactions.
What to Expect Over Time
More frequent urination typically appears after dosing. Swelling may gradually improve with steady use. Blood pressure response can take time and usually requires consistent daily tablets plus lifestyle measures. Your prescriber may order periodic blood tests to check electrolytes and kidney function. Maintain routine follow-ups and share any symptoms you notice, especially dizziness, cramps, or weakness.
Some patients also use single-ingredient diuretics. To understand how this combination relates, see individual options like Hydrochlorothiazide and Spironolactone.
Compare With Alternatives
Doctors may consider other potassium-sparing combinations if this therapy is not suitable. Options can include Amilzide or Triazide, depending on your medical history and lab profile. Choice depends on individual factors and the treatment plan set by your prescriber.
Pricing and Access
You can review selection and place an order online. Many people compare Spironolactone HCTZ price with other diuretics to manage overall care budgets. Canadian sourcing with robust pharmacy checks supports value-conscious choices. We list current options and include packaging details when available.
Some patients also look at Spironolactone HCTZ cost alongside single-ingredient medicines to plan therapy. See seasonal offers on our Promotions page. We provide transparent listings with clear product details and US fulfilment. Ships from Canada to US for eligible orders.
Availability and Substitutions
Supply can vary. If a specific strength or brand is not available, your prescriber may recommend a comparable alternative. We will dispense the product specified on your valid prescription or a pharmacist-approved substitute when permitted by your prescriber and local regulations. Prescription required and verified.
Patient Suitability and Cost-Saving Tips
This treatment may suit adults who need a combination diuretic for blood pressure or edema and for whom potassium balance requires attention. It may not suit people with significant kidney impairment, high potassium, Addison’s disease, or sulfonamide allergies. Report all medicines, including over-the-counter agents and herbal supplements.
- Multi-month supply: Ask your prescriber about 60- or 90-day fills to reduce monthly copays and trips.
- Steady routine: Take at the same time each day; set a phone reminder.
- Lab checks: Keep scheduled blood tests for electrolytes and kidney function.
- Refill planning: Start your Spironolactone HCTZ refill online a few days before you run low.
Questions to Ask Your Clinician
- What goals are we targeting for blood pressure and swelling with this combination?
- How often should I check electrolytes and kidney function while on this medicine?
- Do I need to avoid potassium-rich foods or supplements with my current plan?
- Could a single-ingredient diuretic work as well for my situation?
- What signs suggest dehydration or high potassium that I should report quickly?
- Are there medicines I should limit, like NSAIDs, while taking this therapy?
Authoritative Sources
DailyMed: Spironolactone and Hydrochlorothiazide
Health Canada DPD: Spironolactone/Hydrochlorothiazide
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What conditions does this combination tablet treat?
This diuretic combination is used to help manage high blood pressure and to reduce swelling from excess fluid. Clinicians also use it for edema associated with heart failure, cirrhosis, or certain kidney disorders. By combining two mechanisms, it can support blood pressure goals and fluid control where a single agent is not enough. Your prescriber will decide if this therapy fits your plan based on medical history, lab results, and any other medicines you take.
How should I take the tablets during the day?
Most adults take the medication once daily, sometimes twice daily, exactly as prescribed. Many people prefer morning dosing to limit nighttime urination, but timing should follow the label your prescriber provides. Take with food if needed for stomach upset. Do not change your schedule without talking to a healthcare professional. If you miss a dose, take it when remembered unless it is close to the next one, and never double up.
What side effects should I watch for?
Common effects include more frequent urination, dizziness, headache, nausea, rash, and sensitivity to sunlight. Some people notice breast tenderness or menstrual changes. More serious issues can include high potassium, low sodium, dehydration, kidney problems, or significant drops in blood pressure. Seek urgent care for symptoms like muscle weakness, irregular heartbeat, confusion, severe vomiting, or very low urine output. Always report concerning symptoms to your prescriber promptly.
Can I take potassium supplements with this medicine?
Do not start potassium supplements or salt substitutes unless your prescriber advises it. One part of this combination conserves potassium, so extra intake can raise the risk of high potassium, which may be dangerous. Your clinician may check electrolytes regularly and adjust your broader plan. Also tell your prescriber about ACE inhibitors, ARBs, or other agents that can increase potassium levels.
Does it interact with other medications?
Yes, interactions can occur. ACE inhibitors, ARBs, and other potassium-sparing therapies may increase potassium. NSAIDs can reduce the diuretic effect and stress the kidneys. Lithium levels may rise when taken with diuretics. Alcohol can intensify dizziness or low blood pressure. Provide your full medication and supplement list to your clinician to help prevent problems and ensure the therapy is appropriate for you.
What is the difference between this combo and separate pills?
The combination places two diuretics in a single tablet, which can simplify routines and support potassium balance. Separate pills may offer more flexible dosing in certain cases, but they add complexity. Your prescriber considers blood pressure targets, swelling, kidney function, and laboratory values when choosing between a combination tablet and individual components. Convenience, tolerance, and monitoring needs also factor into the decision.
How should I store the tablets, especially when traveling?
Keep tablets at room temperature, protected from moisture and light, and stored in the original labeled container. When traveling, carry them in your hand luggage with a copy of your prescription or a recent pharmacy receipt. Use a small pill organizer if it helps your routine. Keep the medicine away from children and pets, and avoid storing it in bathrooms or hot cars where humidity and heat can build up.
