How does this medicine work on the immune system?

Ustekinumab targets two signaling proteins called interleukins 12 and 23. These cytokines influence immune cells involved in inflammation. By binding to them, the treatment reduces activation of pathways that promote plaque formation in psoriasis, joint inflammation in psoriatic arthritis, and intestinal inflammation in IBD. The result can be steadier control over symptoms for some patients. Your response depends on your condition and overall health. Your prescriber will monitor safety and effectiveness over time.

Can I use the prefilled syringe at home?

Yes, many people self-inject at home once a healthcare professional provides training. A clinician should demonstrate the steps first. Use clean hands, rotate sites, and avoid areas that are tender, bruised, or affected by active plaques. Follow the official Instructions for Use included with your medicine. If you prefer, a caregiver can be trained to inject. Contact your prescriber if you are unsure whether home administration is appropriate for you.

What should I do before each injection?

Check the carton and the syringe expiration date. Inspect the solution; do not use it if it looks discolored, cloudy, or contains large particles. Let the syringe reach room temperature as directed by the label before injecting. Choose a new injection site and clean the skin with an alcohol swab. Gather supplies, including your sharps container. If anything seems unusual, call your pharmacist or prescriber for guidance before proceeding.

Are vaccines allowed while on therapy?

Avoid live vaccines during treatment, as they may increase infection risk when combined with immunosuppressive therapy. Inactivated vaccines are generally considered, but your clinician will advise based on your medical history. If possible, update needed immunizations before starting therapy. Always inform your healthcare team about upcoming vaccinations so they can plan timing around your treatment schedule.

How is this different from intravenous induction?

Some conditions start with an intravenous infusion under clinical supervision. After that, many patients transition to subcutaneous maintenance using the prefilled syringe. The IV induction delivers a weight-based dose quickly, while the syringe enables ongoing doses at set intervals. Your prescriber decides the approach, timing, and dose based on your diagnosis and prior response. Always follow the plan in your prescription and the approved label.

What if I miss a scheduled injection?

Take the missed dose as soon as you remember unless it is almost time for your next dose. If the next injection is near, skip the missed dose and continue with the regular schedule. Do not take two doses at once. If you are unsure what to do, contact your prescriber or pharmacist. Keeping a calendar or reminder on your phone can reduce the chance of missed doses.

How should I dispose of used syringes?

Place used syringes immediately into an FDA-cleared sharps container. If one is not available, use a heavy-duty household container with a tight, puncture-resistant lid until you can access proper disposal. Do not discard loose needles in household trash or recycling. When the container is nearly full, follow local or state rules for disposal or sharps mail-back services. Your pharmacist can help locate community resources.

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Stelara Prefilled Syring

Stelara® Prefilled Syringe for Adults

Crohn's Disease, Psoriasis, Psoriatic Arthritis, Ulcerative Colitis

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Stelara is a prescription biologic supplied in a ready-to-use prefilled syringe. It helps manage certain immune-driven conditions in adults. You can access US delivery from Canada, which may reduce out-of-pocket strain. Many people compare options by searching for Stelara Prefilled Syringe without insurance to understand their choices.

What Stelara Is and How It Works

Stelara® contains ustekinumab, a monoclonal antibody. It targets interleukins 12 and 23, proteins that drive inflammatory pathways. By lowering these signals, the treatment can calm overactive immune responses seen in plaque psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

This medicine is given as a subcutaneous injection. Your prescriber determines the schedule based on your condition and prior therapy. For skin conditions, dosing often includes an initial period followed by maintenance at longer intervals. For inflammatory bowel disease, an initial intravenous dose is usually followed by ongoing subcutaneous injections. Always follow your healthcare professional’s directions and the official label.

To learn more about the conditions it treats, see our guides on Psoriasis and Crohns Disease. These resources explain symptoms, goals, and how biologic therapy fits into care plans.

Who It’s For

The Ustekinumab prefilled syringe is indicated for adults with moderate to severe plaque psoriasis and active psoriatic arthritis. It is also used for adults with moderate to severe Crohn’s disease and ulcerative colitis, as outlined in the product’s official labeling. People with active, serious infections should not start therapy until infections are controlled.

Tell your prescriber if you have a history of chronic or recurrent infections, tuberculosis exposure, or if you are scheduled for live vaccines. Share all current medicines and conditions, including pregnancy or plans to breastfeed. Safety and suitability depend on your medical history and clinical evaluation.

Dosage and Usage

The Stelara Prefilled Syringe is used subcutaneously in the thigh, abdomen, or upper arm. Your prescriber will determine a starting schedule and maintenance interval appropriate for your diagnosis. For skin conditions, there is typically an initial dose and a second dose weeks later, then regular maintenance injections. For inflammatory bowel disease, subcutaneous dosing usually follows an initial intravenous infusion.

Have a clinician or trained person show you how to inject. Wash and dry your hands. Choose an injection site and rotate locations to reduce skin irritation. Do not inject into areas that are tender, bruised, thickened, or affected by active psoriasis plaques. Remove the cap only when you are ready to inject, and do not recap after use. If you are new to self-injection, this step-by-step overview may help: How To Inject Mounjaro. Refer to your medication’s Instructions for Use for the exact steps.

Strengths and Forms

The prefilled syringe is typically available in two strengths: 45 mg/0.5 mL and 90 mg/mL. Availability may vary by supply, jurisdiction, and your prescription. Your prescriber chooses the appropriate presentation and quantity based on your condition and dosing schedule.

Missed Dose and Timing

If you miss a dose, take it as soon as you remember unless it is close to your next scheduled injection. If the next dose is near, skip the missed dose and continue with your regular schedule. Do not double up doses. If you are uncertain what to do, contact your prescriber or pharmacist for guidance aligned with the official label.

Storage and Travel Basics

Keep the syringes in the original carton to protect from light. Store refrigerated according to the product label and do not freeze. Do not shake the syringe. If your label allows room-temperature storage for a limited time, note the time window and do not return it to the refrigerator once kept at room temperature. Keep out of reach of children and pets.

When traveling, pack the carton in an insulated bag with cool packs to maintain temperature within the recommended range. Do not place syringes directly against ice. Carry your prescription and a copy of the Instructions for Use. Allow extra time for security screening and keep the medicine with you, not in checked baggage. This medicine may require temperature-controlled handling when required.

For related conditions and care, explore Ulcerative Colitis and Psoriatic Arthritis. These pages discuss disease management and supportive therapies.

Pen Handling and Sharps Disposal

This product is a prefilled syringe, not a pen, but the steps for safe handling are similar. Inspect the solution before use. Do not use if it looks discolored, cloudy, or contains large particles. Use each syringe only once. After injecting, place the used syringe immediately into an FDA-cleared sharps container. If you do not have one, use a heavy-duty household container with a tight-fitting, puncture-resistant lid until you can obtain a proper sharps container.

Do not throw loose needles or syringes into household trash or recycling. Follow local or state guidance for disposal. Your pharmacist can advise on community programs or mail-back services.

Benefits

This treatment can help reduce inflammatory activity associated with plaque psoriasis, psoriatic arthritis, and inflammatory bowel disease. It may lower the frequency of flares and improve skin or joint symptoms. Compared with some therapies, the maintenance interval is relatively infrequent, which many people find convenient. Subcutaneous administration at home may reduce in-clinic visits once you are trained and stable on therapy.

Side Effects and Safety

Common effects may include upper respiratory tract infections, headache, tiredness, redness or discomfort at the injection site, and nausea. These are often mild to moderate. Allergic reactions can occur. Seek medical help if you develop hives, trouble breathing, or swelling of the face, lips, or throat.

Common: injection site redness, headache, fatigue, mild cough
Gastrointestinal: stomach discomfort, nausea
Infections: cold-like symptoms, sinusitis

Serious risks include severe infections, tuberculosis reactivation, and rare neurological reactions. Your clinician may screen for latent TB before starting therapy. Report signs of infection such as fever, persistent cough, or weight loss. Avoid live vaccines during treatment. If you are on insulin or sulfonylureas for diabetes, discuss hypoglycemia risk related to illness or reduced intake with your prescriber.

Drug Interactions and Cautions

Avoid live vaccines while receiving therapy. Tell your healthcare professional about all prescription and over-the-counter medicines, vitamins, and herbal supplements. Other immunosuppressants may increase infection risk when used together. If you receive phototherapy or other biologics, your clinician will assess whether combination use is appropriate.

Before starting, inform your prescriber about infections, cancer history, or any planned surgery. If you become pregnant or plan to breastfeed, discuss the benefits and potential risks so your care team can tailor the plan.

What to Expect Over Time

Responses vary. Some people notice gradual improvement in skin, joint, or bowel symptoms over time. Steady adherence to the prescribed schedule is important for consistent control. Keep a simple log of injection dates, sites, and how you feel. Share this log during appointments to help your clinician evaluate progress. Do not change your schedule without guidance; refer to the official label and your prescriber’s instructions.

Compare With Alternatives

Other biologic therapies are available for similar conditions. Options include IL-23 and IL-17 inhibitors. Your prescriber may consider agents such as Skyrizi Pre Fill Cartridge or Cosentyx based on your diagnosis, prior response, and safety considerations. Each option has distinct dosing intervals and monitoring needs. Discuss benefits, risks, and administration preferences with your clinician to find a good fit.

Pricing and Access

We offer Canadian pharmacy access for brand-name biologics. Review the Stelara Prefilled Syringe price on our product page to see current options. You can also compare Ustekinumab injection price to understand potential savings. We provide clear information for cash-pay buyers and those working with insurance reimbursement on their own.

For many people, Canadian pricing paired with US shipping from Canada can be helpful. Final amounts depend on your prescribed strength, quantity, and any dispensing fees. Prescription required and verified. To view availability and request a quote, check the product page and contact our pharmacy team if you need assistance.

Availability and Substitutions

Supply can vary due to manufacturer production and demand. If an item is temporarily unavailable, your prescriber may recommend an alternative that suits your condition and treatment goals. We can coordinate with your healthcare professional to support a safe switch if directed.

Some patients request Stelara Prefilled Syringe from Canada to align with their prescriber’s plan and budget. If your clinician approves a substitution, our team can help confirm Canadian brand sourcing and ensure the proper presentation.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults with moderate to severe plaque psoriasis, active psoriatic arthritis, or inflammatory bowel disease who need systemic treatment. It may not be right for people with certain active infections or those who require live vaccines. Work with your clinician to review your medical history and decide on the right approach.

Plan refills: set reminders a week before your next dose
Bundle fills: ask about multi-month quantities when appropriate
Coordinate travel: ship early to maintain your schedule
Track response: use a symptom and injection log
Check coverage: submit receipts if your plan allows out-of-network claims

For broader therapy context, see our Immunology category. You may also find these articles helpful: Enbrel Injection Uses and Arthritis Drugs.

Questions to Ask Your Clinician

Is this therapy appropriate for my condition and history?
What maintenance interval do you recommend for me?
How should I handle vaccinations while on treatment?
What signs of infection should I report right away?
Can I store a dose at room temperature before injecting?
How should I time refills to avoid gaps in therapy?

Authoritative Sources

For full prescribing information and Instructions for Use, consult official resources:

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View All FAQs

How does this medicine work on the immune system?
Ustekinumab targets two signaling proteins called interleukins 12 and 23. These cytokines influence immune cells involved in inflammation. By binding to them, the treatment reduces activation of pathways that promote plaque formation in psoriasis, joint inflammation in psoriatic arthritis, and intestinal inflammation in IBD. The result can be steadier control over symptoms for some patients. Your response depends on your condition and overall health. Your prescriber will monitor safety and effectiveness over time.
Can I use the prefilled syringe at home?
Yes, many people self-inject at home once a healthcare professional provides training. A clinician should demonstrate the steps first. Use clean hands, rotate sites, and avoid areas that are tender, bruised, or affected by active plaques. Follow the official Instructions for Use included with your medicine. If you prefer, a caregiver can be trained to inject. Contact your prescriber if you are unsure whether home administration is appropriate for you.
What should I do before each injection?
Check the carton and the syringe expiration date. Inspect the solution; do not use it if it looks discolored, cloudy, or contains large particles. Let the syringe reach room temperature as directed by the label before injecting. Choose a new injection site and clean the skin with an alcohol swab. Gather supplies, including your sharps container. If anything seems unusual, call your pharmacist or prescriber for guidance before proceeding.
Are vaccines allowed while on therapy?
Avoid live vaccines during treatment, as they may increase infection risk when combined with immunosuppressive therapy. Inactivated vaccines are generally considered, but your clinician will advise based on your medical history. If possible, update needed immunizations before starting therapy. Always inform your healthcare team about upcoming vaccinations so they can plan timing around your treatment schedule.
How is this different from intravenous induction?
Some conditions start with an intravenous infusion under clinical supervision. After that, many patients transition to subcutaneous maintenance using the prefilled syringe. The IV induction delivers a weight-based dose quickly, while the syringe enables ongoing doses at set intervals. Your prescriber decides the approach, timing, and dose based on your diagnosis and prior response. Always follow the plan in your prescription and the approved label.
What if I miss a scheduled injection?
Take the missed dose as soon as you remember unless it is almost time for your next dose. If the next injection is near, skip the missed dose and continue with the regular schedule. Do not take two doses at once. If you are unsure what to do, contact your prescriber or pharmacist. Keeping a calendar or reminder on your phone can reduce the chance of missed doses.
How should I dispose of used syringes?
Place used syringes immediately into an FDA-cleared sharps container. If one is not available, use a heavy-duty household container with a tight, puncture-resistant lid until you can access proper disposal. Do not discard loose needles in household trash or recycling. When the container is nearly full, follow local or state rules for disposal or sharps mail-back services. Your pharmacist can help locate community resources.