Stelara® (ustekinumab) Prefilled Syringe for Psoriasis, PsA, Crohn’s, and UC

What Stelara® Is and How It Works

Stelara® (ustekinumab) is a biologic medicine for immune-mediated diseases. It helps manage moderate to severe plaque psoriasis, active psoriatic arthritis, moderate to severe Crohn’s disease, and moderate to severe ulcerative colitis. This listing is for the prefilled syringe given by subcutaneous injection. The usual dosing is one injection at week 0 and week 4, then every 12 weeks for skin and joint disease. In inflammatory bowel disease, dosing follows an IV induction, then 90 mg under the skin every 8 weeks. If you are comparing options, you may also be checking the Stelara Prefilled Syring price or how to order Stelara Prefilled Syring online. Many people also ask about Stelara Prefilled Syring without insurance.

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Dosage and Usage

Follow your prescriber’s exact directions. Doses depend on your condition and weight. The prefilled syringe is for subcutaneous use only. A healthcare professional may train you to inject at home.

• Plaque psoriasis and psoriatic arthritis: Inject at week 0 and week 4, then every 12 weeks. Adults 45 mg or 90 mg based on weight and response.
• Crohn’s disease and ulcerative colitis: Start with a single weight-based IV infusion. Then inject 90 mg under the skin at week 8 after the infusion, and every 8 weeks ongoing.
• Injection sites: Thigh, abdomen, or outer upper arm if someone else administers. Rotate sites. Do not inject into tender, bruised, thickened, or scarred skin.
• Before use: Keep in the carton. Let the syringe warm to room temperature for about 30 minutes. Do not heat, do not shake.
• Missed dose: Take it as soon as you remember unless it is near the next dose. If it is close, skip the missed dose. Resume your regular schedule. Ask your prescriber for advice if you miss more than one dose.

• Storage: Refrigerate at 2–8°C (36–46°F). Do not freeze. Protect from light in the original carton. If needed, you may keep a syringe at room temperature (up to 30°C / 86°F) for up to 30 days. Do not return it to the fridge. Discard if not used within that period.
• Travel: Keep in insulated packaging with cool packs. Do not place directly on ice. Carry on the plane, not in checked baggage. Keep the original label and a copy of your prescription.
• Disposal: Use a sharps container for used syringes and needles. Follow local rules for disposal.

Do not use the syringe if it is frozen, shaken, cracked, or discolored. The liquid should be clear to slightly opalescent and colorless to light yellow with a few fine particles possible.

Benefits and Savings

Stelara® targets interleukin-12 and interleukin-23. This reduces inflammation that drives psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. Many people see durable control with infrequent maintenance dosing. For skin disease, dosing every 12 weeks can lower the treatment burden. For bowel disease, every-8-week injections support long-term remission plans.

You can often save 60–80% versus typical US prices by ordering through YouDrugstore. We ship to the US, and our team supports simple reorders. If you pay out of pocket or need Stelara Prefilled Syring without insurance, our multi-month options and bulk promotions can reduce the per-month cost.

Side Effects and Safety

All medicines can cause side effects. Most are mild, but serious events can occur. Review risks with your prescriber before starting.

• Common: headache, nasal congestion or sore throat, upper respiratory infection, tiredness, dizziness, redness or pain at the injection site, diarrhea, stomach pain, nausea, sinusitis, joint pain, itching.
• Less common: tooth infections, flu, abdominal pain, vomiting, vaginal yeast infection, back pain.
• Serious: severe infections (including tuberculosis), cancer, allergic reactions (including anaphylaxis), posterior reversible encephalopathy syndrome (PRES) with sudden headache, confusion, seizures, or vision changes, reactivation of latent infections.

Screen for tuberculosis before treatment. Tell your healthcare professional if you have chronic or recurrent infections, or a history of cancer. Avoid live vaccines during treatment. Infants exposed in utero to biologics may need adjusted vaccine timing; discuss this with the pediatrician.

Stop the drug and seek urgent care for signs of severe infection, allergic reaction, or neurologic symptoms suggestive of PRES. Report persistent injection-site reactions or new skin lesions.

Onset Time

Response timing varies by condition. In plaque psoriasis, some people see improvement within 2 weeks, with clearer skin often by 12 weeks. In psoriatic arthritis, joint symptoms may ease over 4–12 weeks. In Crohn’s disease and ulcerative colitis, many respond within 3–6 weeks after the IV induction, with further gains by 8–16 weeks of maintenance.

Compare With Alternatives

Several biologics treat these conditions. TNF inhibitors are long-standing options. For example, Humira® treats psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis with every-other-week or weekly injections. Ustekinumab offers a different target and less frequent maintenance dosing for some indications.

Interleukin inhibitors also include Skyrizi® Pre Fill Cartridge W Injector for psoriasis and psoriatic arthritis, with different dosing schedules, and Rymti® Pre Filled Injection (etanercept biosimilar) for psoriasis and psoriatic arthritis.

Your prescriber will weigh diagnosis, severity, comorbidities, infection risk, dosing frequency, and prior response when comparing options.

Combination Therapy

Stelara® may be used alone or with other treatments, depending on the condition. In psoriatic arthritis, it can be used with methotrexate. In psoriasis, topical therapies or phototherapy may be added during flares. In inflammatory bowel disease, it may be used with aminosalicylates, steroids for short courses, or immunomodulators when appropriate. Your care team will tailor therapy to your goals and risk profile.

Patient Suitability and Cost-Saving Tips

Tell your prescriber about current infections, TB history, cancer history, vaccination status, and all medicines you take. Share if you are pregnant, planning pregnancy, or breastfeeding. Discuss your goals for skin, joint, or bowel control, and your comfort with injections and monitoring.

Cost matters. Compare the Stelara Prefilled Syring cash price and your Stelara Prefilled Syring out of pocket options. YouDrugstore offers multi-month supplies where appropriate. Buying more than one month can lower the per-month cost. We also send friendly reorder reminders so you can stay on track.

For current deals and bulk options, see our promotions page; if you search for a Stelara Prefilled Syring coupon, you will find active offers there.

If you are researching condition details, our category pages for Crohns Disease and Plaque Psoriasis can help you learn more. You can also read our articles Psoriasis Action Month 2025 Advocating For Support And Solutions and The Abdomen Part Iii The Right Lower Quadrant for general educational context.

If you need Stelara Prefilled Syring without insurance, compare total costs across doses and consider planned refills. Ask your provider if a longer interval, once you are stable, fits your plan. Never change your schedule without medical guidance.

Authoritative Sources

Review official documents to understand full risks and directions. See the manufacturer’s Prescribing Information and Medication Guide (Janssen), Health Canada’s Drug Product Database Entry for Ustekinumab, and the FDA’s Stelara Ustekinumab Label.

YouDrugstore helps you access Canadian pharmacy pricing with careful pharmacist review. Order with confidence and receive prompt, express, cold-chain shipping to the US.

This content does not replace medical advice. Always follow your prescriber’s directions and the package insert approved for your region.