Stribild® Tablets for HIV-1: Uses, Dosing, and Safety

What Stribild® Is and How It Works

Stribild is a once-daily complete antiretroviral regimen for HIV-1. It combines four medicines in one tablet: elvitegravir (an integrase inhibitor), cobicistat (a boosting agent), emtricitabine, and tenofovir disoproxil fumarate. The tablet is taken with food. Therapy aims to suppress the virus, increase CD4 counts, and prevent disease progression.

YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba; prescriptions are reviewed by licensed pharmacists before dispensing.

If you compare Stribild price options, Canadian pricing can lower out-of-pocket costs, even without insurance. You can buy Stribild online at YouDrugstore and place a secure US order. Sourcing follows strict standards: we also partner with licensed, vetted international pharmacies to supply authentic brand HIV medicines at fair prices and with a broad selection.

How it works: elvitegravir blocks viral DNA integration. Cobicistat raises elvitegravir levels by slowing its breakdown. Emtricitabine and tenofovir block reverse transcriptase, which the virus needs to copy itself. Used daily, Stribild lowers viral load and helps achieve and maintain an undetectable level when taken as prescribed.

Indication: treatment of HIV-1 infection as a complete regimen in adults and in adolescents meeting weight and age criteria per label. Do not use with other antiretrovirals.

Dosage and Usage

• Standard dose: one tablet by mouth once daily with food.
• Swallow whole. Do not crush, split, or chew.
• Do not coadminister with other HIV medicines. Stribild is a complete regimen.
• Missed dose: take as soon as remembered if not close to the next dose. Skip if it is almost time for the next. Do not double doses.
• Vomiting: if vomiting occurs soon after dosing, follow label or clinician guidance on whether to take another tablet.
• Antacids containing aluminum/magnesium: separate by several hours to limit absorption issues.
• Strong enzyme inducers (for example, rifampin or St. John’s wort) are contraindicated due to loss of effect.
• Renal function: initiation is not recommended below defined creatinine clearance thresholds in the label; monitor kidney function during therapy.

• Store at 20–25 °C (68–77 °F); excursions 15–30 °C (59–86 °F).
• Keep in the original bottle with the desiccant. Close tightly to protect from moisture.
• Keep away from heat and humidity. Do not store in a bathroom.
• For travel, use your carry-on. Keep the labeled container for security checks.
• Do not leave tablets in a hot car. Avoid long sun or heat exposure.
• Bring extra doses for delays. Set phone reminders for consistent timing.

Benefits and Savings

Stribild simplifies therapy by combining four agents in one pill taken daily with food. Many patients reach undetectable viral load within months when adhering to therapy. The fixed-dose coformulation supports adherence, which lowers the risk of resistance and improves long-term outcomes.

Ordering through YouDrugstore offers access to Canadian pricing. Typical savings are 60–80% versus common US pharmacy charges. This helps reduce Stribild cost for cash-paying customers and supports a clear Stribild price comparison against local options. You can place a Stribild online order and ship to your US address.

We show competitive Stribild cash price options and periodic Stribild deal opportunities. Multi-month supplies and bulk promotions may lower the per-month rate. Savings can be significant even without insurance.

To see current offers, visit our Stribild coupon page.

Side Effects and Safety

• Common effects: nausea, diarrhea, headache, fatigue, dizziness.
• Other reported: insomnia, abnormal dreams, rash, stomach pain, flatulence.
• Kidney-related effects can occur with tenofovir disoproxil fumarate; providers monitor lab values.
• Reductions in bone mineral density have been observed.
• Increases in serum creatinine may occur with cobicistat without true GFR change.
• Immune reconstitution syndrome may appear as the immune system recovers.

Serious risks include lactic acidosis and severe hepatomegaly with steatosis, renal impairment including Fanconi syndrome, and severe exacerbations of hepatitis B after stopping therapy in those coinfected. Not all drugs are compatible because cobicistat is a strong CYP3A inhibitor; serious interactions can occur with certain antiarrhythmics, sedatives, ergot derivatives, rifamycins, some statins, and anticonvulsants. Avoid St. John’s wort. Pregnancy can reduce elvitegravir/cobicistat exposure; alternatives may be preferred during pregnancy. Breastfeeding is not recommended for people with HIV.

Onset Time

Viral load typically begins to fall within the first few weeks. Many patients see a substantial decline by 2–4 weeks and continue toward suppression as dosing remains steady. Achieving an undetectable viral load often occurs within 8–24 weeks, depending on baseline viral load, adherence, and individual factors. CD4 count recovery usually progresses over months.

Compare With Alternatives

Genvoya® contains elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide (TAF) instead of tenofovir disoproxil fumarate. TAF tends to have a more favorable kidney and bone profile. Genvoya can be considered in patients who need that profile and has different renal initiation thresholds. Dosing remains one tablet daily with food.

Triumeq® combines dolutegravir, abacavir, and lamivudine. It is one tablet daily and does not require a booster. Abacavir requires HLA-B*5701 testing to reduce the risk of hypersensitivity. In hepatitis B coinfection, additional agents are needed to cover HBV. Choice among regimens considers resistance, comorbidities, and interactions.

Combination Therapy

• Stribild is a complete regimen; do not use with other antiretrovirals.
• Opportunistic infection treatments (for example, azoles or macrolides) may require interaction checks due to cobicistat.
• Statins: avoid simvastatin and lovastatin; consider alternatives at adjusted doses.
• Acid-reducing agents: separate polyvalent cation antacids; review H2 blocker and PPI use for potential effects on exposure.
• Anticonvulsants, rifamycins, and certain herbal products are contraindicated or not recommended.

Patient Suitability and Cost-Saving Tips

Stribild is intended for adults and eligible adolescents as a complete regimen. It is not advised to initiate below labeled renal function thresholds, and monitoring during therapy is important. Those with known osteoporosis risk or a history of kidney issues may need a different option. In pregnancy, alternative regimens are often preferred because elvitegravir/cobicistat exposure can decrease.

Medical history matters. Review current medicines, including over-the-counter and supplements, for interactions. Do not use Stribild with other HIV agents. People with chronic hepatitis B need careful management when starting or stopping tenofovir- and emtricitabine-containing regimens.

To manage budget needs, check current Stribild tablets for sale listings on our site and compare the Stribild best price on different pack sizes. Reorder reminders can help you avoid gaps. Multi-month fills may reduce the per-month Stribild cost. These options support those paying without insurance or using a cash purchase.

Authoritative Sources

Gilead Stribild Prescribing Information

Health Canada Drug Product Database: Stribild

FDA Label and Medication Guide for Stribild

Order Stribild® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This page is educational and does not replace advice from your healthcare professional. Always follow your prescriber’s instructions and the official patient information.