Tivicay

HIV, HIV Infection

$247.99 – $723.99

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We are committed to providing you with safe and affordable medication when you need it. In anticipation of the upcoming Canada Post strike, we have secured alternative shipping options to avoid delays.

We strive to keep costs as low as possible but please note that with the increased costs associated with alternatives available while Canada Post services are interrupted, additional fees may apply.

For orders with Canadian products that are less than $300, a $35 surcharge will be applied to your order. There are no additional fees for orders of $300 or more.

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Tivicay (dolutegravir) is an Integrase Strand Transfer Inhibitor (INSTI) used in the treatment of HIV infection. It is part of a combination regimen with other antiretrovirals for patients who are INSTI-naïve or have specific profiles of HIV resistance. Dolutegravir works by inhibiting the HIV replication enzyme integrase, disrupting the formation of infectious virions.

Benefits

Tivicay is effective in managing HIV infection as part of a combination therapy. It helps reduce the viral load in the body, improving immune function and reducing the risk of HIV-related complications.

How to Use

Tivicay is available in film-coated tablets and can be taken with or without food. It is always used in combination with other antiretroviral drugs. Dosage adjustments may be necessary when taken with certain medications. Patients with mild or moderate hepatic impairment can use Tivicay without dosage adjustment, but it is not recommended for those with severe hepatic impairment. Caution is advised for patients with severe renal impairment.

Possible Side Effects

Osteonecrosis
Hepatotoxicity
Viral resistance
Immune reactivation syndrome
Rash

For a comprehensive list of potential adverse effects, refer to the product monograph.

Warnings and Precautions

Serious rashes and organ dysfunction due to hypersensitivity reactions have been reported. Tivicay may increase the risk of depression and suicidal thoughts, particularly in patients with pre-existing psychiatric conditions. Patients with HIV should be screened for HBV and HCV co-infections, and appropriate treatment should be initiated.

Drug Interactions

Tivicay has numerous drug-drug and herbal interactions. Consult the product monograph for detailed information.

Pregnancy and Lactation

During pregnancy, highly active antiretroviral therapy should be used regardless of viral load and CD4 count. Tivicay is associated with neural tube defects if used in the first trimester. Consult current guidelines for treating pregnant women. The excretion of dolutegravir in breast milk is unknown, and breastfeeding is not recommended for HIV-positive women to prevent virus transmission.

Overdosage

In case of overdose, standard supportive care and monitoring should be provided. Dolutegravir is likely not dialyzable.

Express Shipping - from $25.00

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United States (all contiguous states**)
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Standard Shipping - $15.00

Shipping with this method takes 5-10 days

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Dry-Packed Products $15.00
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