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Tolterodine (Generic for Detrol®/Detrol LA®) for Overactive Bladder
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What Tolterodine Is and How It Works
Tolterodine is an antimuscarinic medicine used to treat overactive bladder. It helps reduce urinary frequency, urgency, and urge incontinence. The drug blocks muscarinic receptors in the bladder detrusor muscle. This lowers involuntary contractions and increases bladder capacity. Extended-release capsules are often available as tolterodine 4 mg, and immediate-release tablets are usually 1 mg or 2 mg. People may refer to tolterodine tartrate 4mg when describing the extended-release option. You may also see brand references such as Detrol® or Detrol LA®.
Youdrugstore is a licensed Canadian pharmacy in Manitoba that follows Canadian pharmacy standards. Our pharmacists review each prescription before dispensing. We offer brand and generic options at Canadian prices, and also carry OTC health products. Ordering is easy online, and customer-service chat is available during posted office hours.
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Dosage and Usage
Follow your prescriber’s directions on formulation and strength. Tolterodine comes as immediate-release tablets and extended-release capsules.
- Starting doses: Immediate-release tablets are often 2 mg twice daily. Extended-release capsules are often 4 mg once daily.
- Adjustments: If not tolerated, clinicians may adjust to 1 mg twice daily or 2 mg once daily, depending on the formulation and response.
- How to take: Swallow extended-release capsules whole. Do not crush or chew. Tablets and capsules can be taken with or without food at the same times each day.
- Missed dose: Take it when remembered unless it is near the next dose. Skip the missed dose if close to the next scheduled time. Do not double doses.
- Special populations: Dose adjustments may be needed in hepatic or renal impairment, or when taking strong CYP3A4 inhibitors.
- Storage: Store at room temperature, 15–30°C (59–86°F), in a dry place away from light.
- Travel: Keep medicine in original labeled packaging. Carry it in your hand luggage when flying. Bring extra in case of travel delays.
Benefits and Savings
Tolterodine reduces urinary urgency and frequency and helps cut urge incontinence episodes. Many patients see fewer bathroom trips and less leakage. Extended-release dosing offers once-daily convenience. Generic tolterodine provides the same active ingredient as Detrol®/Detrol LA® at a lower cost.
Ordering from Youdrugstore can lower overall tolterodine price compared with typical US pharmacy costs. Savings of 60–80% are common versus US retail pricing. This applies to common strengths such as tolterodine 4 mg and tolterodine 2 mg. Multi-month supplies can further reduce the per-month cost.
Side Effects and Safety
Tolterodine has known anticholinergic effects. Many are mild and dose-related. Serious effects are less common but need prompt care.
- Common: dry mouth, constipation, headache, dizziness, dry eyes, blurred vision, abdominal discomfort.
- Less common: fatigue, indigestion, urinary tract infection, cough.
- Serious: difficulty urinating or urinary retention, severe abdominal pain, rapid or irregular heartbeat, signs of allergic reaction (hives, swelling, trouble breathing).
- Warnings: Not suitable for uncontrolled narrow-angle glaucoma, urinary retention, or gastric retention. Use caution with hepatic or renal impairment. Interactions can occur with strong CYP3A4 inhibitors (for example, ketoconazole or clarithromycin) and with other anticholinergic drugs.
Always follow the guidance of your prescriber and pharmacist and read the patient leaflet that comes with your medication.
Onset Time
Some symptom relief can begin within the first one to two weeks. Bladder stability and reduced urgency often continue to improve over several weeks. Full benefits may take eight weeks for certain patients. Keep taking tolterodine as prescribed unless your prescriber advises a change.
Compare With Alternatives
Tolterodine is one of several options for overactive bladder. Other antimuscarinics include solifenacin and fesoterodine. Beta-3 agonists, such as mirabegron, work differently and may be used when antimuscarinics are not suitable or as add-on therapy.
Solifenacin is a once-daily antimuscarinic that may be easier to tolerate for some people. You can review pricing and supply options for Vesicare® if your prescriber recommends solifenacin. Fesoterodine is closely related to tolterodine and is typically dosed once daily. See Toviaz® to compare strengths and costs.
Oxybutynin is another antimuscarinic, available as tablets, ER tablets, and patches. Choice depends on side-effect profile, daily routine, comorbidities, and insurance coverage. Your clinician will help select the best agent and dose.
Combination Therapy
Clinicians sometimes combine an antimuscarinic with a beta-3 agonist when single-agent therapy does not meet goals. Combination therapy can improve efficacy with careful monitoring for blood pressure changes and anticholinergic burden. Pelvic floor training and bladder training can also support symptom control alongside medication.
Patient Suitability and Cost-Saving Tips
Tolterodine is used for what many describe as classic overactive bladder symptoms: urgency, frequency, and urge incontinence. It is intended for adults and may be considered after lifestyle measures. People with urinary retention, gastric retention, or uncontrolled narrow-angle glaucoma should not use it. Those with liver or kidney impairment may require lower doses. Discuss your full medication list to avoid interactions.
Use generic tolterodine to reduce costs compared with branded Detrol LA uses. Ask about multi-month supplies and bulk promotions to lower the monthly price further. You can set gentle reorder reminders so you do not run out. For current offers, see our tolterodine coupon page, which also covers bulk options when available.
Learn more about the condition in our Overactive Bladder and Urinary Incontinence condition pages. For comparisons and therapy tips, read Effective Myrbetriq Alternatives Options For Bladder Health and What Is Overactive Bladder Signs Causes And Relief.
People often compare tolterodine cost across pharmacies and coupons, including tolterodine goodrx listings. Canadian pharmacy pricing offers value on tolterodine tartrate 4 mg cost and tolterodine tartrate 2mg price. You can review tolterodine tablets and extended-release options with our team if you have product questions.
Authoritative Sources
Review the Pfizer product page for Detrol LA for brand background and labeling. See the FDA Prescribing Information for Tolterodine Tartrate for dosing and safety details. You can also search the Health Canada Drug Product Database for Canadian listings.
Youdrugstore is ready to help with questions about strengths, quantities, and refills. Our pharmacists review prescriptions for safety and accuracy, and our support team can guide your order. We offer prompt, express, cold-chain shipping to the United States when required by the product.
This information is not a substitute for medical advice. Always speak with your healthcare provider about diagnosis, treatment choices, and any side effects you experience.
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What is tolterodine used for?
Tolterodine treats overactive bladder symptoms, including urinary urgency, frequency, and urge incontinence. It blocks muscarinic receptors in the bladder to reduce involuntary contractions. The medicine is available as immediate-release tablets and extended-release capsules. It is commonly chosen when lifestyle measures and bladder training have not provided enough relief.
What is the usual tolterodine dose?
Many patients start on 2 mg twice daily for tablets or 4 mg once daily for extended-release capsules. Some need lower doses due to side effects or other conditions. Do not change your dose without guidance. Ask your prescriber if tolterodine 4 mg is suitable for your formulation and treatment plan.
How long does tolterodine take to work?
Some people notice fewer urgency episodes within one to two weeks. Benefits can build over several weeks, with fuller effect by about eight weeks. Continue taking tolterodine as directed unless your prescriber advises a change. Reach out to your clinician if symptoms persist or worsen over time.
What are common tolterodine side effects?
Common effects include dry mouth, constipation, blurred vision, dizziness, and dry eyes. Many effects are mild and improve with time or dose changes. Seek urgent care for trouble urinating, severe abdominal pain, fast heartbeat, rash, swelling, or breathing problems. Review your medication list for interactions with your prescriber or pharmacist.
Can tolterodine be taken with other bladder medicines?
Clinicians sometimes combine an antimuscarinic with a beta-3 agonist when single therapy is not enough. Your prescriber will consider blood pressure, anticholinergic burden, and other conditions. Never start or stop medicines on your own. Share all prescriptions, OTC products, and supplements with your healthcare team to check for interactions.
How should I store and travel with tolterodine?
Store at room temperature, 59–86°F (15–30°C), in a dry place away from sunlight. Keep it in the original labeled container. When flying, pack it in carry-on luggage and bring extra for delays. Do not crush or chew extended-release capsules. Follow your prescriber’s instructions on timing each day.
How can I save on tolterodine cost?
Choose generic tolterodine rather than brand Detrol LA when possible. Compare quantities for better per-month pricing, and consider multi-month supplies. Ask about current promotions and bulk offers. Many customers see 60–80% savings versus typical US prices, including for tolterodine 4 mg strength.