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Tolterodine LA for Overactive Bladder (Generic for Detrol LA®)
Price range: $77.99 through $184.99
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What Tolterodine LA Is and How It Works
Tolterodine LA is the extended-release form of tolterodine tartrate. It is used for adults with overactive bladder to reduce urinary frequency, urgency, and urge incontinence. The once-daily capsule releases medicine slowly over 24 hours to help control bladder muscle contractions throughout the day.
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Tolterodine blocks muscarinic receptors (mainly M2/M3) in the bladder. This action calms involuntary detrusor muscle spasms and increases bladder capacity. Typical strengths include tolterodine LA 4mg and 2mg. The long-acting design aims to provide steady symptom control while limiting peaks that can worsen dry mouth or constipation.
Common clinical goals include fewer bathroom trips, less nighttime waking, fewer urgency episodes, and fewer leaks. These align with standard Detrol LA uses. The medicine is prescription-only and not an over the counter option. It is often considered when behavioral measures alone are not enough.
Dosage and Usage
- Usual adult dose: 4 mg once daily. Some people start at 2 mg once daily, especially with liver impairment or interacting medicines.
- Swallow the capsule whole. Do not crush, split, or chew the long-acting beads.
- Take at the same time each day, with or without food.
- If you miss a dose, take it when remembered unless it is close to the next dose. Do not double up.
- Tell your prescriber about strong CYP3A4 inhibitors (for example, ketoconazole or clarithromycin). A 2 mg daily dose may be advised in those cases.
- Report troublesome dry mouth, constipation, or difficulty urinating to your prescriber. These may require dose changes.
- The tolterodine tartrate ER dosage is individualized. People with severe liver disease or urinary retention usually should not use it.
- Storage: keep capsules at 15–25 °C (59–77 °F) in a dry place, away from moisture and direct light.
- Short excursions up to 30 °C (86 °F) are generally acceptable. Avoid excessive heat or freezing.
- Store in the original, child-resistant container with the pharmacy label.
- For travel, pack in your carry-on with a copy of your prescription. Keep the labeled bottle to avoid delays.
- A travel pill case is fine, but keep the original container for security checks and identification.
- Do not store in a bathroom. Humidity can affect capsules.
Benefits and Savings
Tolterodine LA offers once-daily dosing in a long-acting capsule, which supports steady control of urgency and frequency. Many people find it easier to use than multiple daily doses. Extended-release tolterodine may cause less dry mouth than some older anticholinergics. The medicine has well-studied outcomes in overactive bladder.
Choosing the generic detrol la 4 mg can lower monthly spend compared with the brand. Many customers see 60–80 % savings versus typical U.S. prices, and multi-month supplies can reduce the per-month cost further. You can set reorder reminders so you do not run out.
We work with licensed, vetted international partner pharmacies to provide authentic brand medications, a wide selection, and competitive pricing.
For seasonal deals and updates, see our promotions; the tolterodine coupon may be listed when available.
Some shoppers compare detrol la price and detrol la cost between brand and generic. The detrol la generic (tolterodine LA) provides the same active ingredient and dose options, including detrol la 4mg and detrol la 2mg equivalents. Always follow your prescriber’s plan.
Side Effects and Safety
- Dry mouth
- Constipation
- Headache
- Dry eyes or blurred vision
- Dizziness or drowsiness
- Abdominal pain or indigestion
- Fatigue
- Urinary tract discomfort
Serious but less common risks include difficulty urinating or urinary retention, severe constipation, allergic reactions (rash, swelling, trouble breathing), confusion, and worsening narrow‑angle glaucoma. Use is generally avoided in urinary retention, gastric retention, or uncontrolled narrow‑angle glaucoma. Strong CYP3A4 inhibitors can raise levels; a lower dose may be preferred. In hepatic impairment, a lower dose (2 mg daily) or avoidance may be needed. The side effects of tolterodine 4mg are similar to other anticholinergics; using the lowest effective dose can reduce risk.
Onset Time
Some people notice fewer bathroom trips in 1–2 weeks. Urgency and leakage episodes often continue to improve through weeks 4–8 as steady-state exposure is maintained. Optimal benefit can take several weeks, especially when starting at 2 mg before moving to 4 mg as tolerated.
Track symptom patterns over time, such as daily voids and leaks, to gauge response. If changes plateau or side effects limit use, speak with your prescriber about alternatives or dose adjustments.
Compare With Alternatives
Tolterodine LA (detrol la generic) is bioequivalent to the brand. Those who prefer a non-extended option may consider Tolterodine immediate-release tablets, typically taken twice daily. Some find once-daily long-acting capsules easier to keep consistent.
Other antimuscarinic choices include Toviaz® (fesoterodine), which is also taken once daily and may help when tolterodine is not enough, and Vesicare® (solifenacin), another once-daily option. These medicines share similar side effects and precautions but differ in dosing ranges and individual responses.
Non-anticholinergic therapy includes mirabegron (a beta‑3 agonist), often used when anticholinergic effects are hard to tolerate. You can also read about OAB basics in What Is Overactive Bladder Signs Causes And Relief and consider broader options discussed in Effective Myrbetriq Alternatives Options For Bladder Health.
Combination Therapy
- Tolterodine LA with mirabegron for added control of urgency and frequency.
- Behavioral measures such as bladder training, pelvic floor exercises, and timed voiding.
- Fluid and caffeine moderation to reduce triggers.
- When combining agents, prescribers may use lower doses to limit dry mouth and constipation.
Patient Suitability and Cost-Saving Tips
Good candidates include adults with bothersome urgency, frequency, or urge incontinence due to overactive bladder. It is not for stress incontinence. Careful use is needed in older adults sensitive to anticholinergic effects, and in those with cognitive impairment, chronic constipation, or bladder outlet obstruction.
Tolterodine LA is usually avoided in urinary retention, gastric retention, and uncontrolled narrow-angle glaucoma. People with moderate liver impairment may need a 2 mg daily dose; severe liver disease may preclude use. Discuss pregnancy and breastfeeding with a clinician. The tolterodine tartrate cap 4mg ER should be swallowed whole to maintain release properties.
To save on treatment, choose generic when appropriate, compare detrol la price options, and consider a 2–3 month supply. Bulk promotions can lower the per‑month cost. Set a reorder reminder in your account so you receive your next refill on time. If you are comparing detrol la alternatives, review choices like Toviaz® or Vesicare® with your prescriber and weigh benefits against side effects.
For condition background and lifestyle ideas, visit our Overactive Bladder page or read Myrbetriq Side Effects You Should Know About to understand another class used for OAB.
Authoritative Sources
Pfizer Detrol LA Product Information
Health Canada Drug Product Database: Tolterodine
FDA Label: Detrol LA (tolterodine tartrate) Extended-Release Capsules
Order Tolterodine LA from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express shipping.
This content is educational and does not replace professional medical advice. Always speak with a qualified healthcare provider about diagnosis and treatment choices.
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What is Tolterodine LA and how does it work?
Tolterodine LA is an extended-release antimuscarinic used for overactive bladder. It relaxes bladder muscles by blocking M2/M3 receptors, which helps reduce urgency, frequency, and leaks. The long-acting capsule delivers medicine over 24 hours, so most people take a single daily dose at the same time each day.
What is the usual Detrol LA dosage in adults?
Most adults use 4 mg once daily; some start at 2 mg once daily. A 2 mg dose may be used with strong CYP3A4 inhibitors or in hepatic impairment. Swallow capsules whole. Your prescriber will tailor the tolterodine tartrate ER dosage based on response and tolerability.
How long does Tolterodine LA take to work?
Some improvement can appear within 1–2 weeks, with urgency and frequency often improving further by weeks 4–8. Response varies by person and dose. If benefit is limited or side effects are troublesome, your prescriber may consider dose changes or an alternative therapy.
What are common Detrol LA side effects?
Common effects include dry mouth, constipation, headache, dry eyes or blurred vision, dizziness, abdominal discomfort, and fatigue. Serious reactions can include urinary retention, severe constipation, allergic reactions, and worsening narrow-angle glaucoma. Seek urgent care for swelling, trouble breathing, or severe difficulty urinating.
Is Detrol LA over the counter?
No. Detrol LA and its generic, Tolterodine LA, require a valid prescription. Pharmacists must review prescriptions before dispensing. If you need help with renewals, contact your prescriber. Compare detrol la cost and options, and consider generic to reduce out-of-pocket expenses where appropriate.
What is the difference between Detrol LA 4 mg capsule and 2 mg?
Both capsules contain extended-release tolterodine tartrate. The 4 mg dose provides a higher daily exposure than 2 mg and may benefit persistent symptoms. The 2 mg dose is often chosen for sensitive patients, liver impairment, or with strong CYP3A4 inhibitors. Your prescriber decides the right strength.
How much does Tolterodine LA cost and can I save?
Tolterodine LA typically costs less than the brand, Detrol LA. Many customers save 60–80% compared with typical U.S. prices by ordering from Canada. Buying a multi‑month supply can lower the per‑month price. Tolterodine LA is the focused choice for value and once-daily convenience.