Triazide® Tablets for Hypertension and Edema Management

What Triazide® Is and How It Works

Triazide is a prescription combination of triamterene and hydrochlorothiazide used to treat high blood pressure and fluid retention (edema). It comes as oral tablets, often in strengths such as 50/25 mg. Many people also search for triazide without insurance to manage costs while staying on therapy. YouDrugstore is a licensed Canadian pharmacy headquartered in Manitoba; pharmacists review prescriptions before dispensing, and we offer brand and generic medicines at Canadian prices with online or phone ordering, OTC options, and customer-service chat during posted hours.

This medicine pairs two diuretics. Hydrochlorothiazide increases sodium and water excretion in the distal tubule. Triamterene blocks epithelial sodium channels and helps conserve potassium. Together they reduce excess fluid and lower blood pressure while limiting potassium loss.

Dosing is typically once daily in the morning. Some patients may need a higher strength or a split dose based on response and lab results. This product is used for essential hypertension, edema in heart failure, cirrhosis, certain kidney conditions, or medication-related fluid retention, as directed by a prescriber.

Dosage and Usage

• Usual adult start: one tablet once daily in the morning; strength and frequency are individualized.
• Titration: dose may be adjusted after clinical and lab review to reach blood pressure or edema goals.
• Administration: take at the same time each day; taking with food can reduce stomach upset.
• Hydration: maintain normal fluid intake unless told otherwise by a clinician.
• Lab monitoring: periodic potassium, sodium, and kidney function checks are standard.
• Missed dose: take when remembered the same day unless close to the next dose; never double.
• Bedtime dosing is generally avoided to limit nighttime urination.
• Photosensitivity may occur; consider sun protection.
• Switching from separate components may require dose recalculation by the prescriber.
• Common marketed strengths include 37.5/25 mg, 50/25 mg, and 75/50 mg equivalents depending on region and brand.

• Store tablets at 15–25 °C (59–77 °F) in a dry place, away from moisture.
• Keep in the original, tightly closed bottle; do not store in a bathroom.
• Protect from excessive heat and direct sunlight.
• If a desiccant is present, leave it in the bottle and do not ingest.
• For travel, pack enough doses plus extras in your carry-on with a copy of the prescription.
• Use a pill organizer only if humidity is controlled; otherwise keep in the original bottle.
• Do not freeze or refrigerate.

Benefits and Savings

Triazide helps reduce blood pressure and controls swelling from excess fluid. The potassium-sparing component may reduce the need for separate potassium supplements. Once-daily dosing supports adherence. Generic options are widely used and can lower the triazide cost compared with legacy brands.

Ordering from Canada can offer meaningful savings. Many customers save 60–80% versus typical US prices, especially on multi-month supplies. Bulk options can decrease the per-month triazide price, and reorder reminders help maintain continuity. If paying cash, the triazide cash price at checkout is transparent, which can help those buying triazide without insurance.

We work with licensed, vetted international partner pharmacies to source authentic brand medicines and quality generics, offering a broad selection at affordable pricing.

For current deals, see our triazide coupon page for promotions that may apply to your order.

Side Effects and Safety

• Increased urination, especially soon after dosing
• Dizziness or lightheadedness
• Headache
• Nausea or stomach upset
• Dry mouth or thirst
• Muscle cramps or weakness
• Rash or photosensitivity
• Mild changes in lab electrolytes

Serious effects are less common and require prompt medical attention. These include high potassium (weakness, slow or irregular heartbeat), low sodium (confusion, seizures), severe dehydration, kidney problems, kidney stones, pancreatitis, jaundice, severe rash, or significant drops in blood pressure. Risk of high potassium increases with ACE inhibitors, ARBs, potassium supplements, salt substitutes, or other potassium-sparing diuretics. People with sulfonamide allergy may react to hydrochlorothiazide. Triazide can affect blood sugar control; when combined with insulin or sulfonylureas, glucose may drop more than expected, so monitoring is important.

Onset Time

Diuretic effects can start within hours of a dose. Blood pressure improvements are often seen within 1–2 weeks, with full effect by 4 weeks as the dose and labs stabilize. Edema usually eases over several days, and may continue to improve over 1–2 weeks. Electrolytes can shift within the first week, so early lab checks are common after changes.

Compare With Alternatives

Hydrochlorothiazide alone is a long-standing first-line diuretic for hypertension. It can be effective but may lower potassium, which some patients do not tolerate. Triazide combines a thiazide with a potassium-sparing agent to help balance electrolytes.

Chlorthalidone is a thiazide-like diuretic with a longer half-life. It may reduce blood pressure more strongly in some patients but can also increase the chance of low potassium and low sodium. Clinicians may supplement potassium if needed.

Other potassium-sparing combinations, such as amiloride with hydrochlorothiazide or spironolactone-based regimens, are options when potassium conservation is a priority. Choice depends on kidney function, electrolyte history, drug interactions, and blood pressure or edema goals.

Combination Therapy

• ACE inhibitor or ARB plus Triazide for hypertension; monitor potassium and kidney function.
• Beta-blocker or calcium channel blocker added for multi-drug blood pressure control.
• Loop diuretic short term for refractory edema; watch for dehydration and electrolyte shifts.
• Diabetes medicines may need adjustment to reduce hypoglycemia risk as fluid status changes.
• Avoid duplicate potassium-sparing diuretics unless specifically directed by a specialist.

Patient Suitability and Cost-Saving Tips

Good candidates include adults with hypertension or edema who benefit from a diuretic and who have stable kidney function and electrolyte levels. This medicine may be considered after previous thiazide therapy when potassium loss was an issue. Generic triamterene/hydrochlorothiazide is widely available and is often chosen for cost and convenience.

Those who should not use it include people with high potassium, anuria, significant kidney impairment, or those taking other potassium-sparing diuretics or potassium supplements. Caution is needed with ACE inhibitors, ARBs, NSAIDs, lithium, and in liver disease. Discuss pregnancy and breastfeeding considerations with a clinician.

To lower the triazide cost, consider a 90‑day supply if appropriate, since multi-month fills can reduce per-month pricing. Bulk promotions can help when available. Reorder reminders keep therapy on track. If searching for triazide near me, online ordering can save time and provide clear pricing. For those with triazide no insurance situations, paying by cash at checkout is straightforward.

Authoritative Sources

FDA prescribing information: Triamterene and Hydrochlorothiazide

Health Canada Drug Product Database: Triamterene/Hydrochlorothiazide

Order Triazide® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This content is educational and does not replace advice from your healthcare professional.