Triumeq® (abacavir/dolutegravir/lamivudine) tablets for HIV-1 treatment

What Triumeq Is and How It Works

Triumeq® is a once-daily tablet that treats HIV-1 infection in adults and eligible adolescents. It contains abacavir 600 mg, dolutegravir 50 mg, and lamivudine 300 mg. If you are comparing triumeq cost without insurance, many people check Canadian pricing to plan their budget. The tablet can be taken with or without food and is a complete antiretroviral regimen.

Dolutegravir is an integrase strand transfer inhibitor. It blocks HIV from inserting its genetic material into human DNA. Abacavir and lamivudine are nucleoside reverse transcriptase inhibitors. They suppress viral replication by interrupting DNA chain growth. Together, these agents reduce viral load and support CD4 recovery when taken as prescribed.

YouDrugstore is a licensed Canadian pharmacy based in Manitoba that meets Canadian pharmacy standards. Prescriptions are reviewed by licensed pharmacists before dispensing, and our store carries both brand and generic medicines at Canadian prices with friendly customer-service chat during posted hours. We source through licensed, vetted international partner pharmacies to supply authentic brands at fair, accessible pricing and a broad selection.

Dosage and Usage

Follow your prescriber’s directions and the product label. General guidance:

• Take one Triumeq® tablet once daily.
• Swallow the tablet whole with water. Take with or without food.
• Do not take with other antiretroviral medicines unless directed.
• Antacids or supplements with aluminum, magnesium, calcium, iron, or zinc can reduce dolutegravir absorption. Take Triumeq® 2 hours before or 6 hours after these. If taken with a meal, iron or calcium may be taken at the same time.
• Avoid dofetilide. This combination is contraindicated.

Missed dose:

• If it is within 4–6 hours of the usual time, take the dose now.
• If it is close to the next dose, skip the missed dose and resume the schedule.
• Do not double the dose.

Storage and travel:

• Store at 15–30°C (59–86°F) in a dry place.
• Keep the tablets in the original bottle with the desiccant.
• Carry your medication in hand luggage when you travel.
• Use a daily reminder to support consistent dosing.

Benefits and Savings

Triumeq® simplifies treatment with one pill a day. Dolutegravir provides a high barrier to resistance. Many patients reach undetectable viral load with steady use as part of a full care plan. Tablets are small, and there is no food requirement, which supports daily adherence.

Buying through a Canadian pharmacy can reduce out-of-pocket costs. Typical savings are 60–80% compared with many US retail prices. People paying without insurance often compare our pricing to their local options. Some also review Triumeq cost with insurance to decide between a plan copay and a cash price.

Side Effects and Safety

Common side effects tend to be mild and may improve over time:

• Nausea, diarrhea
• Headache, tiredness
• Trouble sleeping or vivid dreams
• Dizziness

Serious effects are less common and need prompt medical attention:

• Abacavir hypersensitivity reaction. Symptoms can include fever, rash, fatigue, cough, shortness of breath, and gastrointestinal upset. Risk is high with HLA-B*5701. Genetic testing is recommended before starting. Never restart abacavir after a suspected reaction.
• Lactic acidosis and severe hepatomegaly with steatosis. Seek urgent care if deep or rapid breathing, persistent nausea, or stomach pain develops.
• Liver problems, including hepatitis flares after stopping in people co-infected with hepatitis B. Monitor liver function as advised.
• New or worsening depression or anxiety.
• Pancreatitis (rare), especially with lamivudine history.
• Allergic reactions, including swelling of face or throat.

Kidney-related notes: dolutegravir can raise serum creatinine by blocking tubular secretion without reducing true kidney filtration. This usually does not reflect kidney damage. Lamivudine requires dose adjustments in renal impairment; Triumeq® is not recommended if a lower lamivudine dose is needed due to reduced kidney function. Discuss kidney history and lab results with the care team.

Use caution with significant liver disease. Abacavir is not recommended in moderate to severe hepatic impairment. Report cardiovascular risk factors, as some studies have explored a possible abacavir association with myocardial infarction. Review all medicines, including metformin (exposure can increase with dolutegravir), anticonvulsants, rifampin, St. John’s wort, and polyvalent cations.

Onset Time

Viral load often declines within the first 2–4 weeks of treatment. Many patients reach undetectable levels within 8–24 weeks, depending on baseline viral load, adherence, and individual factors. CD4 counts usually rise over months. Keep regular lab monitoring as directed by the prescriber.

Compare With Alternatives

Odefsey® combines emtricitabine, rilpivirine, and tenofovir alafenamide. It is also one tablet daily, usually with a meal. It is not preferred if baseline viral load is high or CD4 is low. You can review current availability on Odefsey®.

Kaletra® (lopinavir/ritonavir) is an older protease inhibitor–based regimen used less often today due to gastrointestinal side effects and pill burden. See details on Kaletra® if a boosted PI is being considered for specific resistance patterns.

Apretude® is long-acting cabotegravir given by injection for HIV prevention (PrEP), not for treatment. It serves a different role but may interest partners or patients seeking prevention options. Learn more on Apretude® Injectable Suspension.

Triumeq PD is a pediatric dispersible formulation for eligible children. Doses are weight-based and differ from the adult tablet.

Combination Therapy

Triumeq® is a complete regimen and should not be combined with other antiretroviral agents unless a specialist directs a change. Clinicians may add medicines to prevent or treat opportunistic infections based on CD4 count and exposure risks. Space or adjust interacting drugs such as antacids, iron, or calcium as described in the dosing section.

Patient Suitability and Cost-Saving Tips

Triumeq® may suit adults and adolescents who need a once-daily, integrase-based regimen and have a negative HLA-B*5701 test. It is not recommended with dofetilide, in moderate to severe hepatic impairment, or when the lamivudine component requires renal dose adjustment. People with hepatitis B co-infection need careful monitoring if stopping or switching therapy.

Discuss pregnancy planning with the prescriber. Dolutegravir is widely used in pregnancy, including early pregnancy, based on expanding safety data. Breastfeeding guidance differs by region and viral suppression status. Follow your care team’s advice.

To manage costs, compare multi-month supplies, which can lower the per-month price. Our team can set simple reorder reminders to help you stay on schedule. For current promos and bulk options, see our Triumeq coupon page. Patients paying without insurance can often save more by choosing Canadian pharmacy pricing.

Explore condition guidance at Hiv and Hiv Infection for related products. For learning, see National Hiv Testing Day 2025 Get Tested Know Your Status and Drug Interactions The Top Interactions That Should Be On Your Radar. If you need details specific to HIV-1 staging, you can also review Hiv 1 Infection.

Authoritative Sources

For full prescribing details, review the manufacturer and regulatory documents:

• ViiV Healthcare Triumeq product information
• Health Canada Triumeq Drug Product Database entry
• FDA Prescribing Information for Triumeq

Order from YouDrugstore, a licensed Canadian pharmacy in Manitoba. Our pharmacists review each prescription, and our customer-service chat is available during posted office hours. Place your order online or by phone where available. We offer prompt, express, cold-chain shipping to the US.

This content is for general education. It does not replace professional medical advice. Always follow your prescriber’s instructions and the official product labeling.