Trulicity® Injection for Type 2 Diabetes

This prescription GLP-1 receptor agonist helps adults manage type 2 diabetes. It is a once-weekly subcutaneous injection used alongside diet and exercise. You can order with US shipping from Canada, and see options that fit your budget without insurance.

What Trulicity Is and How It Works

Trulicity® contains dulaglutide, a GLP-1 receptor agonist. It works by enhancing glucose-dependent insulin secretion, slowing gastric emptying, and reducing glucagon release. These actions help improve blood glucose control. The treatment is used with healthy eating and activity, and may be combined with other diabetes medicines when appropriate.

YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

This medicine is given once weekly, any time of day, with or without food. It is not insulin. It should not be used for type 1 diabetes or diabetic ketoacidosis.

Who It’s For

This therapy is indicated for adults with type 2 diabetes to improve glycemic control. It may also reduce the risk of major cardiovascular events in adults with type 2 diabetes and established cardiovascular disease, as described in the official label. It is not approved for weight loss.

Do not use if you or a family member has a history of medullary thyroid carcinoma, or if you have Multiple Endocrine Neoplasia syndrome type 2. People with a history of pancreatitis should discuss risks with a clinician. It is not recommended for children. Avoid if you have a known hypersensitivity to dulaglutide or any component of the product.

Dosage and Usage

Standard initiation is 0.75 mg under the skin once weekly. A prescriber may increase to 1.5 mg for additional control, and then to 3 mg or 4.5 mg if appropriate. Use the same day each week. If needed, you can change the weekly dose day, as long as there are at least three days (72 hours) between injections. Follow the Patient Information and Instructions for Use provided with your pen.

Inject into the abdomen, thigh, or upper arm. Rotate sites with each injection. Do not share pens. Do not inject into areas that are tender, bruised, scarred, or hardened. Do not mix with insulin or inject into the same site right after insulin. If you use insulin or a sulfonylurea, your clinician may advise closer monitoring to reduce hypoglycemia risk.

Strengths and Forms

Single-dose, prefilled pens are available in commonly used strengths. Your prescriber will select the strength that matches your treatment plan. Each pen contains a single weekly dose.

• Prefilled pen: 0.75 mg
• Prefilled pen: 1.5 mg
• Prefilled pen: 3 mg
• Prefilled pen: 4.5 mg

If you compare packs for budgeting, you may also review dulaglutide pen price in your market.

Missed Dose and Timing

If you miss a dose and there are at least three days until your next scheduled dose, take it as soon as possible. If fewer than three days remain, skip the missed dose and take the next one on the regular day. Do not take two doses within three days of each other. Try to use reminder tools so your weekly schedule stays consistent.

Storage and Travel Basics

Store pens in the refrigerator. Do not freeze. If a pen has been frozen, do not use it. Protect from light by keeping pens in the original carton until use. When needed, a pen can be kept at room temperature for a limited time as noted in the official labeling. Keep out of reach of children and pets.

For travel, pack pens in an insulated bag with a cool source if you will be away from a refrigerator for a long period. Do not place pens directly on ice. Carry your pen, supplies, and prescription label in your hand luggage. Allow the pen to reach room temperature before injection for a more comfortable dose. Dispose of used pens safely after each injection.

Pen Handling and Sharps Disposal

Read the Instructions for Use before your first injection. Wash your hands. Inspect the pen label and check the solution. Let the pen warm to room temperature. Choose and clean an injection site. Unlock and place the pen firmly against the skin. Press the button and hold in place until the window indicates completion, as described in the device guide.

After using the pen, place it in a puncture-resistant sharps container. Do not throw used pens in household trash or recycling. Follow local rules for sharps disposal or use a mail-back program if available.

Benefits

This GLP-1 therapy can lower A1C when used with diet and exercise. Once-weekly dosing may fit well if you prefer fewer injections. Many people notice that digestive side effects improve over time as the body adjusts. The medicine may help reduce the risk of major cardiovascular events in certain adults with type 2 diabetes and established cardiovascular disease, following the product label.

Side Effects and Safety

• Nausea or vomiting
• Diarrhea or abdominal pain
• Decreased appetite
• Indigestion or fatigue
• Injection site reactions

Serious but less common risks include pancreatitis, gallbladder problems, kidney issues, severe gastrointestinal reactions, and allergic reactions. There is a boxed warning about thyroid C-cell tumors. If you use insulin or a sulfonylurea, the combination can increase hypoglycemia risk; ask how to monitor for low blood sugar. Contact a clinician right away for severe or persistent abdominal pain, signs of an allergic reaction, or any symptom that worries you.

Drug Interactions and Cautions

Dulaglutide can slow gastric emptying, which may affect the absorption of certain oral medicines. Extra care may be needed for drugs with a narrow therapeutic index. Alcohol can increase the risk of hypoglycemia when used with insulin or sulfonylureas. Tell your prescriber about all medicines, vitamins, and herbal products you use. If you have severe gastrointestinal disease, talk with your clinician before starting this therapy.

What to Expect Over Time

Glycemic control typically improves with consistent weekly use together with diet and exercise. Digestive effects such as nausea are common at the start and often lessen with continued therapy. Taking time to eat smaller meals and staying hydrated may help. Budgeting for refills becomes easier once you know your dose and schedule, and you can plan around dulaglutide injection price if comparing options.

For broader context on lifestyle, see our article Weight Loss Guide. You can also browse Type 2 Diabetes to explore related therapies.

Compare With Alternatives

Some adults may consider another GLP-1 or an incretin-based option if their prescriber recommends a change. The dual GIP/GLP-1 option Mounjaro Kwikpen offers weekly dosing with a different mechanism. If tablets are preferred, Rybelsus provides oral semaglutide; daily administration and timing rules apply.

To compare broader weight management content, read Weight Loss Injections. For supplies and monitors, see Diabetes Care.

Pricing and Access

Our Canadian pharmacy lists current options and pack sizes so you can estimate your Trulicity price before checkout. If you are evaluating starter doses, some patients also compare dulaglutide 0.75 mg price when planning. You’ll see transparent Canadian pricing, and orders ship discreetly.

We provide secure checkout and US-based customer support for ordering questions. For cross-border convenience, your order Ships from Canada to US when eligible and approved.

Availability and Substitutions

Availability can vary by strength and pack size. If a strength is unavailable, your prescriber may suggest a suitable alternative or a short-term dose adjustment using labeled options. If you are comparing products, review dulaglutide price in context, knowing that this therapy is brand-only at this time. Prescription required and verified.

Patient Suitability and Cost-Saving Tips

You may be a candidate if you are an adult with type 2 diabetes and your clinician believes a GLP-1 is appropriate. You may not be a candidate if you have a history of MTC or MEN2, a serious hypersensitivity to dulaglutide, or if you are pregnant unless your prescriber advises it is appropriate. Tell your healthcare professional about kidney, liver, gallbladder, eye, or stomach problems.

To manage ongoing costs, consider multi-month refills if your prescriber approves. Setting reminders helps you stay on your weekly schedule and avoid rush orders. If you track your total budget, you can plan around insurance deductibles and self-pay options. You might also review seasonal promotions and compare pack sizes once you know your stable dose, so your expected Trulicity monthly cost aligns with your plan.

Questions to Ask Your Clinician

• Is a weekly GLP-1 the right choice for my A1C goals?
• Could current medicines raise my risk of low blood sugar?
• What side effects should I watch for during the first weeks?
• How should I time this injection with meals or other therapies?
• Can we review my Trulicity list price versus alternatives I may consider?

Authoritative Sources

Manufacturer Prescribing Information

FDA DailyMed

Health Canada DPD

Ready to proceed? You can buy Trulicity online from YouDrugstore with express, cold-chain shipping and US delivery from Canada when permitted. Always follow your prescription and the official label. This page is informational and not a substitute for professional medical advice.