Please note: a valid prescription is required for all prescription medication.
Uses of Truqap (Capivasertib)
Truqap (Capivasertib) is a targeted cancer therapy medication developed by AstraZeneca. It’s primarily used in the treatment of certain types of advanced breast cancer.
Truqap (Capivasertib) is a protein kinase B (AKT) inhibitor, used to treat:
- HR-positive, HER2-negative advanced or metastatic breast cancer, especially in patients with tumors carrying specific PIK3CA, AKT1, or PTEN mutations.
- It’s typically used in combination with fulvestrant in adults who have previously received endocrine-based therapy.
It works by blocking the AKT signaling pathway, which plays a key role in the survival and growth of cancer cells.
Precautions and Warnings
Before using Truqap, consider the following:
Genetic Testing Required: The presence of PIK3CA, AKT1, or PTEN mutations must be confirmed before starting therapy.
Blood Sugar Monitoring: Capivasertib can cause hyperglycemia; patients with diabetes or pre-diabetes should be monitored closely.
Heart Monitoring: May prolong the QT interval, increasing the risk of heart rhythm problems. ECG monitoring may be needed.
Liver Function: Monitor liver enzymes periodically.
Fertility and Pregnancy:May harm an unborn baby. Avoid use during pregnancy. Effective contraception is required during treatment and for at least 1 week after the last dose.
Breastfeeding: Not recommended during treatment and for 1 week after the last dose.
Drug Interactions: Avoid strong CYP3A4 inhibitors/inducers (e.g., ketoconazole, rifampin) as they may alter capivasertib levels.
Dosage
- Standard Dose: 400 mg orally, twice daily for 4 days on and 3 days off in a 28-day cycle.
- Taken in combination with fulvestrant.
Side Effects
Common Side Effects:
- Diarrhea
- Nausea and vomiting
- Fatigue
- Rash
- Decreased appetite
- High blood sugar (hyperglycemia)
- Mouth sores
- Elevated liver enzymes
Serious Side Effects:
- Severe rash or allergic reactions
- QT prolongation (irregular heartbeat)
- Severe hyperglycemia or diabetic ketoacidosis
- Visual disturbances (rare)
- Infections due to immune suppression
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If you wish to order prescription medication from YouDrugstore, yes you do need a valid prescription issued by your local doctor. You do not need a prescription to order over-the-counter health products marked as non-prescription or over-the-counter on our website.
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For more information on how to order prescription medication from YouDrugstore, view our How To Order page.
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If you usually take a brand name pill and have instead ordered a generic drug, your pills may look different. Although they may look different, generic versions of a drug have the same active ingredients and work in exactly the same way as the brand-name medication. The appearance of medication or packaging may also differ from country to country, even though the strength is the same. For example, Celexa 20MG is usually a peach-colored pill, but in Canada it is white and slightly smaller, even though the same company manufactures both pills. Two different brands of generic medication may also look different because they are made by different manufacturers, although they are equivalent in every other way.
How does medication from Canada differ from medication in other regions of the world?
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