Truvada

Emtricitabine and Tenofovir Disoproxil Fumarate is used in the treatment of HIV/AIDS. Its newest use is as a pre-exposure prophylaxis, commonly known as PrEP.

Benefits

Truvada is used as part of a regimen of antiretroviral medications to treat HIV-1 in adults. It combines two anti-HIV drugs, emtricitabine and tenofovir disoproxil fumarate, and must be taken with at least one other anti-HIV medication to prevent HIV from progressing to AIDS.

How to Use

Truvada is taken orally once a day, at the same time every day, with or without food. Patients with renal impairment should consult their healthcare provider for specific dosing instructions.

Possible Side Effects

Common side effects include:

• Rash
• Headache
• Nausea
• Vomiting
• Diarrhea

Rarer side effects documented include:

• Discoloration of palms and soles
• Abnormal triglyceride levels
• Abdominal pain
• Lactic acidosis
• Anorexia
• Hepatotoxicity
• Flatulence

Other adverse effects have been reported, so inform your doctor if you experience any health changes when beginning treatment.

Warnings and Precautions

Immune reconstitution syndrome may occur after starting Truvada. Patients, especially those with previous renal impairments, should be monitored for toxicity and to ensure the HIV viral load remains undetectable. Research on safety in patients with liver disorders is inconclusive. Some patients with hepatitis B have experienced exacerbation of symptoms after discontinuing Truvada. Notify your doctor of any sudden changes in body fat or bone structure.

Storage

Store Truvada at room temperature, away from excess heat and moisture. Keep it out of reach of children.

Additional Information

Truvada can heighten the risk of renal complications when taken with certain medications. Pregnant women should consult their healthcare provider, and breastfeeding is not recommended for mothers infected with HIV. In case of overdose, seek medical treatment immediately.