Uceris® Rectal Foam for Ulcerative Colitis

Uceris® Rectal Foam without insurance treats mild to moderate ulcerative proctitis and proctosigmoiditis. This topical steroid targets local inflammation in the rectum and sigmoid colon. Get US shipping from Canada through YouDrugstore for convenient access and verified quality.

What Uceris Is and How It Works

YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.

This medicine contains budesonide, a glucocorticoid designed for local effect in the distal colon. The foam spreads to coat inflamed mucosa, which can reduce bleeding, urgency, and rectal discomfort. Budesonide has high first-pass metabolism, so systemic exposure may be lower than with some oral steroids at labeled doses. The treatment works by decreasing inflammatory mediators and mucosal edema. For disease details and support topics, see our Ulcerative Colitis condition page.

Who It’s For

This therapy is indicated for adults with active, mild to moderate ulcerative proctitis or proctosigmoiditis. It may be appropriate when topical therapy is preferred or when symptoms remain localized to the rectum and sigmoid. Budesonide Rectal Foam is generally not a first choice for extensive colitis beyond the reach of rectal treatments. People with hypersensitivity to budesonide or any component should avoid it. Use caution with untreated infections, tuberculosis, or systemic fungal disease. Safety in pediatric patients is not established.

Some individuals using other rectal anti-inflammatory options, such as Salofalk Suppositories, may be switched if a prescriber determines a steroid is needed. Your clinician will decide based on symptom location and severity.

Dosage and Usage

Follow the official label and your prescriber’s instructions. A commonly used schedule for induction is one dose twice daily for two weeks, then once nightly for an additional four weeks. The canister must be shaken before use. Attach a new applicator, gently insert, and fully depress to deliver the dose. Remain in position briefly to help retention. If possible, apply after a bowel movement and at bedtime. Uceris Rectal Foam 2 mg is for rectal use only and not for oral administration.

Tips for proper use include checking expiry, priming if directed, and disposing of each single-use applicator after administration. If you are transitioning from oral steroids, your prescriber will guide any taper to reduce withdrawal risk. Do not exceed the prescribed frequency or duration.

Strengths and Forms

This product is supplied as a pressurized rectal foam delivering a metered dose of budesonide. The commonly referenced strength is Budesonide Rectal Foam 2 mg per actuation. Kits typically include canisters and multiple single-use applicators. Availability may vary by market and pack size.

Missed Dose and Timing

If you miss a dose, apply it when remembered unless it is close to the next scheduled time. Do not use extra foam to make up a missed dose. Many patients use bedtime dosing to aid retention. For twice-daily regimens, spaced morning and evening timing is often used. If frequent bowel movements interfere with retention, discuss strategies with your healthcare professional.

Storage and Travel Basics

Store the canister at room temperature as directed on the label. Keep away from heat sources and open flames, as the container is pressurized. Do not puncture or incinerate the canister, even when empty. Protect from excessive heat, do not freeze, and keep out of reach of children. Retain the original carton and instructions for reference.

For travel, pack the canister upright in a protective pouch. Carry-on storage is preferred to avoid extremes. Bring your prescription label for security checks. If you are flying, review airline rules for aerosol items. For digestive health topics, you can also read our brief guide on IBS Causes.

Benefits

This therapy delivers anti-inflammatory action directly to the affected mucosa. Local delivery may help manage rectal bleeding, urgency, and tenesmus. Foam can be easier to retain and may coat uneven surfaces better than some liquid enemas. Many patients appreciate once-daily maintenance during the latter part of induction, as directed by labeling. The class is widely used in distal ulcerative colitis when topical steroids are appropriate.

Side Effects and Safety

• Rectal burning or discomfort
• Abdominal pain or cramping
• Nausea or gas
• Headache
• Constipation or diarrhea
• Rectal irritation or pruritus

Systemic corticosteroid effects can occur, especially with prolonged use or interacting drugs. Serious risks may include hypercorticism, adrenal suppression, increased infection risk, mood changes, and vision problems such as glaucoma or cataracts. Hypersensitivity reactions are rare but possible. Tell a healthcare professional if you experience severe abdominal pain, persistent bleeding, signs of infection, or vision changes. Those using insulin or sulfonylureas should monitor for changes in glucose control.

Drug Interactions and Cautions

Strong CYP3A4 inhibitors can raise budesonide exposure. Examples include ketoconazole, clarithromycin, ritonavir, and itraconazole. Grapefruit and grapefruit juice may also increase levels. Live vaccines should be avoided during significant immunosuppression. Use caution with other steroids, including systemic agents like Prednisone. Patients with moderate to severe hepatic impairment may have higher systemic exposure and require careful monitoring.

If switching from systemic corticosteroids, withdrawal symptoms may occur if tapered too quickly. Report fatigue, joint pain, or mood changes to your prescriber. For related topical steroid options, see Entocort® Enema within our Gastrointestinal category.

What to Expect Over Time

Symptoms may ease as inflammation settles with consistent use. The clinical goal is induction of remission in localized ulcerative colitis affecting the rectum and sigmoid. Your prescriber will assess progress and decide whether to continue, adjust, or transition your regimen. Keep using the foam as directed, even if you feel better, unless your clinician advises otherwise. If symptoms persist or spread, a different treatment strategy may be considered.

Compare With Alternatives

For distal disease, non-steroidal 5-ASA options like Mesalamine enemas or suppositories can be used for induction and maintenance, depending on the case. Systemic therapies such as Xeljanz® XR are approved for moderate to severe ulcerative colitis in adults who need advanced therapy. Some patients may use hydrocortisone foam or liquid enemas as another topical steroid choice. Decisions depend on disease extent, prior response, tolerance, and clinician guidance. For those comparing brands and generics, ask your prescriber whether Generic budesonide rectal foam is suitable.

Pricing and Access

Canadian pharmacy options can make treatment more affordable for many patients. If you want to review the Uceris Rectal Foam price, check our product page for current pricing and supply details. Orders include US delivery from Canada for eligible prescriptions. To look for seasonal offers, visit our Promotions page. Savings depend on your plan and prescriber directions, and checkout is encrypted to protect your information.

Availability and Substitutions

Stock and pack sizes can vary. If this item is unavailable, your prescriber may recommend an alternative topical steroid or a 5-ASA product. Options may include budesonide enemas, hydrocortisone foam, or mesalamine formulations. Your care team will determine the best substitute based on your current symptoms and treatment history. We also carry related items like Pentasa Enema when appropriate.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults with localized active disease who can use rectal treatments. It may not be appropriate for people with severe infections, certain eye conditions without monitoring, or known hypersensitivity to budesonide. Ask about multi-month fills if stable on therapy to reduce repeat fees. Set refill reminders in your account so you do not run out during travel or work. Consider coordinating other GI prescriptions in the same order to minimize separate delivery charges.

Questions to Ask Your Clinician

• Where is my inflammation located, and is foam appropriate
• How long should I use this course before reassessment
• What signs suggest I should contact the clinic promptly
• Could non-steroidal options work for maintenance
• Do my medicines raise budesonide levels via CYP3A4
• How should I taper if I use oral steroids now
• What eye monitoring is recommended with steroid therapy
• Are vaccines safe during this treatment period

Authoritative Sources

FDA DailyMed

Manufacturer: Salix Pharmaceuticals

Health Canada Drug Product Database

Ready when your prescription is? Order from YouDrugstore with US shipping from Canada and prompt, express, temperature-controlled handling when required. This information is not a substitute for professional medical advice; always follow your prescriber’s instructions and the official label.