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Velphoro® Chewable Tablets for Hyperphosphatemia
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Velphoro is a prescription phosphate binder for adults on dialysis. It helps control high blood phosphorus when taken with meals. You can access Sucroferric oxyhydroxide 500 mg without insurance with US delivery from Canada.
What Velphoro Is and How It Works
Velphoro® contains sucroferric oxyhydroxide, an iron-based compound that binds dietary phosphate in the gut. The resulting complexes are not absorbed and are eliminated in the stool. This lowers the amount of phosphorus available to enter the bloodstream. YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
This medicine is chewable and should be taken with meals so it can bind phosphate where it is present. It is minimally absorbed systemically. Dark stools may occur due to the iron content. You can learn more about the condition under our Hyperphosphatemia category.
Who It’s For
This treatment is indicated to control serum phosphorus in adults with chronic kidney disease on dialysis. It may be used as part of a broader renal diet and care plan. People with a known hypersensitivity to sucroferric oxyhydroxide or its components should not use it.
Use caution if you have iron overload disorders. Although systemic absorption is low, discuss your iron parameters with your prescriber. Safety has not been established in children. If you are pregnant, planning to become pregnant, or breastfeeding, ask a healthcare professional about potential risks and benefits.
Dosage and Usage
Sucroferric oxyhydroxide 500 mg chewable tablets are usually taken with each meal. The typical starting schedule in adults on dialysis begins with one tablet per meal and is adjusted by your prescriber based on serum phosphorus results. Chew tablets thoroughly; do not swallow whole. If needed, you may crush and mix with a small amount of soft food.
Consistency matters. Take this medicine with breakfast, lunch, and dinner to match phosphate intake. Do not change your dose without guidance. If you use other oral medicines, ask your clinician about spacing to reduce binding interactions. When uncertain, follow the official product label.
Strengths and Forms
The product is supplied as flavored, brown, chewable tablets. The commonly used presentation is Velphoro 500 mg tablets. Availability may vary by market and stock. The exact packaging and tablet appearance can differ by manufacturer lot.
Missed Dose and Timing
If you miss a dose at mealtime, take it with your next meal. Do not double the next dose. This treatment works at the time of eating, so timing with food is important. Keeping a simple meal-and-dose routine can help you stay on track.
Storage and Travel Basics
Store the tablets at room temperature and keep the bottle tightly closed to protect from moisture. Keep out of reach of children and pets. Do not use tablets that are chipped beyond normal handling or show unusual discoloration.
When traveling, carry your prescription-labeled bottle in your hand luggage. Bring enough tablets for the full trip and a few extra days in case plans change. A copy of your prescription can help with security checks. For privacy and safety, avoid repackaging into unlabeled containers.
Benefits
As a phosphate binder taken with meals, this therapy helps reduce dietary phosphate absorption. By lowering serum phosphorus, it supports your dialysis care plan and aligns with renal diet goals. The chewable form can be convenient for people who prefer not to swallow large tablets.
Side Effects and Safety
- Diarrhea
- Discolored or dark stools
- Nausea or vomiting
- Abdominal discomfort
- Tooth or tongue discoloration
Most effects are gastrointestinal and often relate to the iron content or meal timing. Serious reactions are uncommon but can include hypersensitivity. Tell a healthcare professional if you notice persistent diarrhea, severe abdominal pain, signs of allergy, or changes in iron studies that concern you. If you have diabetes or other chronic conditions, discuss how this therapy fits with your overall plan. See our overview of renal topics in Kidney And Bladder Problems.
Drug Interactions and Cautions
Because it binds in the gut, this medicine can reduce absorption of certain oral drugs. Sensitive products such as levothyroxine and some antibiotics may need to be separated from your binder. Always review your full medication list with a clinician.
When appropriate, space other oral medicines to reduce binding. The need for spacing depends on the specific drug. If you are unsure, your prescriber can advise based on the official label. Some dialysis regimens use anticoagulants; if applicable, continue to follow your clinic’s instructions. For reference items, see Heparin Vial. If your care team recommends this binder, confirm any changes before starting a new schedule. The labeling for a Velphoro 500 mg chewable tablet includes cautions about potential interactions and timing with other oral drugs.
What to Expect Over Time
With regular use at meals and ongoing dialysis, your serum phosphorus may trend toward your target range as defined by your prescriber. Lab monitoring guides dose adjustments. Eating within your renal diet and keeping consistent dosing helps your care team gauge response.
Over time, the dose may be titrated to maintain control as your diet and dialysis plan evolve. This medicine supports your broader regimen; other therapies for kidney health may also be considered by your clinician. For example, some patients with CKD may be prescribed an SGLT2 inhibitor when appropriate; see Dapagliflozin for general reference.
Compare With Alternatives
Phosphate binders differ by active ingredient and formulation. Sevelamer carbonate is a non-absorbed, polymer-based option; see Renvela for a sevelamer product we carry. Another class includes lanthanum carbonate, which is also a chewable option in some markets. Calcium-based binders are additional choices but may increase calcium load. Your prescriber can help select a binder that fits your labs, dietary pattern, and tolerance.
Pricing and Access
Canadian pharmacy sourcing can help you compare the Velphoro 500 mg price with local quotes. You can also review the Sucroferric oxyhydroxide 500 mg price to understand options discussed with your prescriber. Products are supplied at Canadian rates and Ships from Canada to US.
To see current pricing, add the item to your cart and proceed to checkout to view options. If you look for coupons, check our Promotions page for periodic offers. For broader browsing, explore the Other category.
Availability and Substitutions
Supply can vary. If this product is unavailable, a prescriber may recommend a suitable alternative binder to maintain phosphorus control. Do not switch therapies without professional guidance. We cannot provide restock dates, but our team updates availability as stock changes.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults on dialysis who need phosphate control and prefer a chewable option. It may not be appropriate if you have a known allergy to ingredients or specific dietary limitations that conflict with the excipients. Review your full medical history with a healthcare professional.
For potential savings, consider multi-month refills if your prescription allows. This can reduce per-order fees and helps you avoid gaps. Set calendar reminders to request refills a bit before you run low. If your clinician adjusts your dialysis plan, revisit your binder schedule and reorder timing to match your updated regimen. A brief note on checkout: our site uses encrypted checkout to protect your information.
Questions to Ask Your Clinician
- Starting dose plan: How should I begin, and how will we adjust?
- Meal timing: What meals should I pair with each dose?
- Other medicines: Which drugs must I separate from my binder?
- Lab monitoring: How often will we check serum phosphorus and iron studies?
- Dental care: Any tips to minimize tooth discoloration from chewables?
- Diet support: What phosphate-restricted diet guidance should I follow?
Authoritative Sources
Velphoro Official SiteDailyMed: VelphoroHealth Canada Drug Product Database
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How do I take Velphoro with meals?
Take this binder with each main meal, as directed by your prescriber. Chew the tablets thoroughly, since they’re designed to work in the gut by binding phosphate from food. If preferred, you may crush and mix with a small amount of soft food. Do not swallow whole. If you miss a meal-time dose, skip it and resume with your next meal rather than doubling the amount. Always follow the official label for detailed directions.
Can Velphoro affect my other medications?
Yes, as a phosphate binder it can reduce absorption of some oral medicines by binding them in the intestine. Sensitive medicines such as levothyroxine and certain antibiotics may need spacing from the binder. Share a complete medication list with your healthcare professional. They can advise if a separation window is necessary for any drug you take and confirm specifics based on the product label.
What side effects are most common?
The most frequently reported effects are gastrointestinal: diarrhea, discolored stools, nausea, and abdominal discomfort. These often relate to the medicine’s iron content and meal timing. Tooth or tongue discoloration can occur with chewable use. Serious effects are rare, but allergic reactions are possible. Notify a clinician if symptoms persist, worsen, or you experience signs of hypersensitivity.
Who should not use this binder?
Do not use if you have a known allergy to sucroferric oxyhydroxide or other ingredients in the product. People with iron overload disorders should use caution and review iron studies with their prescriber. Safety has not been established in children. If you are pregnant, planning pregnancy, or breastfeeding, ask a healthcare professional to discuss potential risks and benefits.
Is this medicine absorbed into the bloodstream?
Systemic absorption is minimal. The product works locally in the gastrointestinal tract by binding dietary phosphate. The resulting complexes are not absorbed and are excreted in the stool. Because absorption is low, effects on systemic iron are usually limited, though your care team may still monitor labs as part of dialysis care. Follow your prescriber’s guidance and the official label.
How is this different from sevelamer binders?
Sevelamer products are polymer-based binders, while sucroferric oxyhydroxide is iron-based. Both reduce phosphate absorption when taken with meals, but they differ in composition, tablet form, and potential tolerability. Your prescriber will consider your labs, diet, and preferences. Some people prefer chewables. Others do well with tablets or powders. Ask which option best fits your care plan.
Can I travel with my phosphate binder?
Yes. Keep tablets in their original, labeled container and store at room temperature. Pack enough for the entire trip and a few extra days. Carry a copy of your prescription in case you are asked to verify it. Take doses with meals as usual. If your meal schedule shifts due to flights or time zones, resume your typical routine as soon as practical and check in with your healthcare professional if unsure.
