Velphoro® (sucroferric oxyhydroxide) chewable tablets for phosphate control

What Velphoro Is and How It Works

Velphoro® (sucroferric oxyhydroxide) is a phosphate binder for adults with chronic kidney disease on dialysis. It helps reduce high blood phosphate. You take it with meals as chewable tablets. Most people start with 500 mg per meal. Many shoppers compare velphoro 500 mg price when planning monthly treatment costs.

Velphoro® works in the gut. The iron-based compound binds dietary phosphate from food. The bound phosphate passes in the stool, so less is absorbed. It is not for patients with chronic kidney disease who are not on dialysis. Your prescriber will monitor phosphorus levels and adjust the dose.

YouDrugstore is a licensed Canadian pharmacy based in Manitoba. Orders are reviewed by licensed pharmacists before dispensing. You can order online and reach our customer-service chat during posted office hours.

We source from licensed, vetted partner pharmacies to offer authentic brands, a broad selection, and fair pricing across many therapies.

Dosage and Usage

Follow your prescriber’s instructions and the product insert. General guidance:

• Start with 500 mg three times daily with meals.
• Chew or crush tablets completely. Do not swallow whole.
• Titrate in weekly steps based on serum phosphorus.
• Typical daily dose is 1,500–3,000 mg. The studied maximum is 3,000 mg/day.
• Take with food to improve phosphate binding.
• If you miss a dose, skip it. Resume with the next meal. Do not double.

• Separate Velphoro® from medicines that can bind to iron if advised by your prescriber.
• Avoid taking levothyroxine with Velphoro®; discuss timing options.

• Store at room temperature (20–25°C). Short excursions 15–30°C are acceptable.
• Keep tablets dry and in the original container.
• When traveling, pack enough for the trip and a few extra days.
• Keep out of reach of children and pets.

Benefits and Savings

Velphoro® lowers phosphorus when used with meals and a renal diet. It offers a lower pill burden compared with some binders, since each 500 mg tablet has strong binding capacity. The iron compound has minimal systemic absorption. Many patients notice fewer tablets to take at mealtime.

Ordering through YouDrugstore is simple and secure. We offer Canadian pricing and prescriber review by our pharmacy team. Many US shoppers see 60–80% savings compared with typical US retail prices, which helps dialysis patients manage monthly costs.

Side Effects and Safety

Most side effects are gastrointestinal and often mild to moderate. Speak with your prescriber if symptoms persist or worsen.

• Very common: diarrhea, dark stools.
• Common: nausea, vomiting, stomach pain, discolored feces, constipation or loose stools, flatulence.
• Less common: changes in iron labs, tooth discoloration (can be removed by dental cleaning).
• Serious but rare: hypersensitivity reactions (rash, swelling, difficulty breathing). Seek urgent care for signs of allergy.

Drug interactions can occur with medicines that bind to polyvalent cations or that have narrow absorption windows. Levothyroxine should not be taken with Velphoro®. Your prescriber may separate dosing of certain antibiotics or other oral drugs. Bring a full medication list to each appointment.

Velphoro® is for adult patients on hemodialysis or peritoneal dialysis. It is not established for use in children. Tell your prescriber about iron overload disorders, GI motility problems, or recent GI surgery. Pregnant or breastfeeding patients should discuss risks and benefits.

Onset Time

Velphoro® starts binding phosphate with the first dose taken with food. Lab improvements often appear within 1 to 2 weeks. Reaching your target range may take several weeks. Your prescriber will check levels and adjust the dose during titration.

Compare With Alternatives

Several phosphate binders are available. Each has different features, pill burden, and lab effects.

Sevelamer (such as sevelamer carbonate) is a non-calcium, non-metal polymer binder. It does not add calcium, which can be helpful if you have hypercalcemia. Pill burden can be higher, and GI gas or bloating is common.

Calcium acetate is effective and often lower in cost. It can raise calcium levels, which may be a concern if your calcium runs high or when taking vitamin D analogs. Monitoring for hypercalcemia is needed.

Ferric citrate provides phosphate control and can increase iron stores. It may reduce the need for IV iron or ESAs for some patients, but it can raise ferritin and TSAT. Your care team will watch iron labs closely.

Velphoro® offers strong binding per tablet and minimal systemic iron absorption. Choice depends on phosphorus targets, calcium balance, iron parameters, tolerability, and pill burden. Your prescriber will select or combine therapies based on your goals and labs.

Combination Therapy

Some patients need more than one binder to reach targets. Your prescriber may pair Velphoro® with a non-calcium binder or adjust vitamin D, calcimimetic, and dialysis prescriptions together. Avoid calcium overload if taking calcium-based binders. Take binders with meals, and keep a consistent schedule. Regular lab checks guide dose changes.

Patient Suitability and Cost-Saving Tips

Velphoro® suits adults on dialysis who need phosphate control and prefer fewer tablets. It may help if calcium is high or if other binders caused intolerance. It is not for patients not on dialysis. Review your full medication list for possible timing adjustments.

You can lower monthly costs by choosing 2–3 month supplies when appropriate, which often reduces the per-month price. We can send gentle reorder reminders so you do not run out between dialysis sessions. For current promotions and bulk options, see our velphoro coupon page.

We keep pricing transparent at checkout. Many US customers compare Canadian and local pharmacy quotes to plan budgets. If you have questions about your order, our customer-service team can help during posted office hours, and our pharmacists can address medication questions related to your prescription.

Authoritative Sources

Review trusted information before starting any new medicine:

• Velphoro consumer site and product information
• Health Canada Drug Product Database entry
• FDA Prescribing Information for Velphoro

YouDrugstore offers Canadian brand medicines and generics at fair prices, with prescriptions reviewed by licensed pharmacists before dispensing. Order online or by phone, and we will ship with prompt, express, cold-chain shipping as required.

This page offers general information and is not medical advice. Always follow your prescriber’s directions and the product insert for dosing, interactions, and monitoring.