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Verzenio

Cancer

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Price range: $3,734.99 through $3,744.99

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Verzenio is an oral targeted therapy used to treat hormone receptor-positive (HR+), HER2-negative breast cancer. It works by inhibiting CDK4 and CDK6 — proteins that promote cancer cell growth — and is typically used in combination with hormonal therapy or as monotherapy in advanced or metastatic cases.

Benefits

  • Slows the progression of HR+/HER2− breast cancer by blocking key proteins involved in cell division.
  • Can be used with endocrine therapy (like fulvestrant or aromatase inhibitors) or alone.
  • Shown to improve progression-free survival in advanced or metastatic breast cancer.
  • Suitable for both men and women with advanced-stage disease.
  • Oral medication allows for convenient at-home treatment.

Dosage

  • The usual dose is 150 mg to 200 mg taken twice daily, depending on the treatment combination.
  • Doses may be adjusted based on side effects or lab results.
  • Should be taken at the same times every day, with or without food.
  • Tablets must be swallowed whole — do not crush or chew.

Warnings and Precautions

  • Can cause diarrhea, which may lead to dehydration — prompt treatment is important.
  • May lower white blood cell counts, increasing the risk of infection — blood tests are required.
  • Risk of blood clots and lung inflammation — report symptoms such as chest pain or shortness of breath.
  • Can affect liver function — liver tests should be done regularly.
  • Not recommended during pregnancy or breastfeeding.

Usage Instructions

  • Take exactly as prescribed by your doctor, twice a day.
  • Swallow each tablet whole with water.
  • If a dose is missed by more than 6 hours or vomiting occurs, skip that dose and take the next one at the usual time.
  • Do not take two doses at the same time.
  • Continue taking unless instructed to stop by your healthcare provider.

Storage Information

  • Store at room temperature (20°C to 25°C).
  • Keep in the original packaging, away from moisture and heat.
  • Do not remove tablets from the bottle until ready to use.
  • Keep out of reach of children and pets.

Common Side Effects

  • Mild to moderate effects: diarrhea, nausea, fatigue, abdominal pain, decreased appetite, hair thinning, and low white blood cell counts.
  • Serious (seek medical attention): signs of infection (fever, chills), blood clots (leg swelling, chest pain), liver issues (yellowing of skin or eyes), or difficulty breathing.

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