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Viokace® Tablets for Exocrine Pancreatic Insufficiency
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Viokace® is a prescription pancrelipase tablet for adults with exocrine pancreatic insufficiency caused by chronic pancreatitis or pancreatectomy. This page explains how it works, who it suits, and key safety details, with US shipping from Canada. It also outlines options that may lower the Viokace price without insurance.
What Viokace Is and How It Works
This medicine contains pancreatic enzymes from porcine sources. It provides lipase, protease, and amylase to help digest fats, proteins, and carbohydrates. The tablets are not enteric coated, so acid in the stomach can inactivate enzymes. For that reason, the product must be taken with a proton pump inhibitor under your prescriber’s direction.
YouDrugstore is a licensed Canadian pharmacy in Manitoba. Pharmacists review prescriptions before dispensing.
It acts locally in the gut. After you swallow a dose with food, enzymes mix with the meal to support nutrient absorption and reduce steatorrhea and bloating. Systemic absorption of enzymes is not expected.
For more on the condition, see our category page for Exocrine Pancreatic Insufficiency. You can also browse related medicines within Gastrointestinal.
Who It’s For
This treatment is indicated for adults with confirmed exocrine pancreatic insufficiency due to chronic pancreatitis or surgical removal of the pancreas. It is not indicated for cystic fibrosis, and it is not recommended for pediatric use. People with a known allergy to pork proteins or to any tablet component should avoid it. It should not be used during acute pancreatitis or during an acute flare.
Dosage and Usage
Therapy is individualized based on lipase units per kilogram of body weight and the fat content of meals. Typical dosing involves a portion with each meal and snack, adjusted by your prescriber to control symptoms while staying within established safety limits on total daily lipase units. A proton pump inhibitor is co-prescribed to protect enzymes from gastric acid.
General use tips:
- Take doses with meals and snacks as directed by your clinician.
- Swallow tablets whole with liquid; do not crush or chew.
- Space doses throughout the day with food intake.
- Keep a symptom and diet diary to guide titration with your prescriber.
Always follow the official label and your healthcare professional’s instructions for dose selection and adjustments.
Strengths and Forms
The product is supplied as uncoated oral tablets. Commonly published strengths include Viokace tablets 10440 units of lipase and another tablet providing 20,880 units of lipase, each with proportional amounts of protease and amylase. Availability may vary by lot and province.
Missed Dose and Timing
If you miss a dose with a meal, take it as soon as you remember while still eating. If the meal is over, skip the missed dose and resume with the next snack or meal. Do not double up doses. Enzymes should be taken with food to work effectively.
Storage and Travel Basics
Store tablets at room temperature in a dry place. Keep the bottle tightly closed and in the original container with the desiccant. Protect from moisture and humidity. Keep out of reach of children. For travel, pack your prescription label with the medicine in carry-on luggage, keep the container closed between uses, and avoid temperature extremes and damp environments such as bathrooms.
Benefits
With consistent use and appropriate dosing, this therapy can help reduce greasy stools, abdominal discomfort, and excess gas by improving digestion of fats and other macronutrients. Better digestion may support weight maintenance and reduce fat-soluble vitamin losses. Tablets allow precise unit-based titration with meals and snacks, guided by symptom control.
Side Effects and Safety
- Common: abdominal pain, bloating, gas, constipation, diarrhea, nausea, headache.
- Local irritation: mouth or perianal irritation if chewed or with leakage.
- Skin or respiratory reactions in patients sensitive to porcine proteins.
Serious but uncommon risks include fibrosing colonopathy with very high exposures, particularly in some populations, and increased uric acid in urine and blood. Stop the medicine and seek urgent care for signs of severe allergic reaction such as hives, swelling, or trouble breathing. Do not exceed the dose range advised by your prescriber or the product label.
Drug Interactions and Cautions
A proton pump inhibitor is typically co-prescribed to support efficacy because these tablets are not enteric coated. Clinically meaningful drug interactions are uncommon, but always share your full medication list, supplements, and conditions with your clinician. Use caution if you have gout, hyperuricemia, or a history of bowel narrowing. This product is porcine-derived; discuss dietary or religious concerns with your prescriber.
What to Expect Over Time
Symptoms of maldigestion may improve once dosing is aligned to meal size and fat content. Your prescriber may adjust units over time to balance symptom control and safety limits. Consistent dosing with every meal or snack, a simple food diary, and adherence to PPI therapy can improve day-to-day results. If symptoms persist despite appropriate use, contact your healthcare professional to review diet, timing, and dose.
Compare With Alternatives
Some patients use enteric-coated pancrelipase capsules such as Creon®, which are designed to resist stomach acid without a PPI. Others may use different capsule brands prescribed for EPI. Non-enteric tablets like this one require a PPI but can offer flexible unit-based titration. If your prescriber recommends capsules, our Gastrointestinal selection shows additional options. Many adults also ask if they should buy pancrelipase tablets; your clinician can advise the best format for your condition.
Pricing and Access
We make Viokace Canadian pricing visible before checkout so you can compare options. If you are researching the pancrelipase tablets price, review the product page for strength, quantity, and current availability, then upload your prescription for verification. Orders are filled by Canadian pharmacists and Ships from Canada to US for eligible addresses.
Looking for periodic offers? See our current Promotions. Any discounts vary by item and may change. Prescription required and verified.
Availability and Substitutions
If stock is limited, your prescriber may suggest an alternative pancrelipase product or adjust the strength to reach the target units. You can order Viokace online with a valid prescription, or ask your clinician if an enteric-coated capsule is appropriate for you.
Patient Suitability and Cost-Saving Tips
Good candidates are adults with confirmed EPI due to chronic pancreatitis or pancreatectomy who can take a PPI. Those with pork protein allergy, acute pancreatitis, or pediatric patients should not use this therapy. To manage the pancrelipase tablets cost, consider multi-month fills if appropriate, set refill reminders, and keep dose records to avoid wastage. When traveling, pack extra tablets in separate bags and carry your prescription to streamline security checks.
Questions to Ask Your Clinician
- Starting dose plan: how many lipase units per meal and snack?
- PPI choice: which proton pump inhibitor and timing with meals?
- Diet guidance: target fat intake and meal spacing with therapy?
- Titration rules: what symptoms suggest increasing or reducing units?
- Safety limits: maximum daily units and when to call the clinic?
- Monitoring: weight, stool quality, and vitamin levels to track?
Authoritative Sources
Health Canada Drug Product Database
For broader GI care topics, you can read about Dificid 200 Mg or explore pancreas-related awareness in Diabetes Month 2025. For swallowing disorders within GI care, see Jorveza. Hepatology therapies tied to digestive health include Baraclude.
Ready to proceed at YouDrugstore? Add your prescription and place your order for prompt US delivery from Canada, with temperature-controlled handling when required. Information here is educational and not a substitute for professional medical advice. Always follow your prescriber and the official label.
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Do I need a PPI with Viokace?
Yes. These tablets are not enteric coated, so gastric acid can inactivate enzymes. A proton pump inhibitor reduces stomach acid, helping lipase, protease, and amylase work in the intestine. Your clinician will choose the PPI and timing relative to meals. If you experience ongoing symptoms despite adherence, ask whether your PPI dose, timing, or enzyme units should be adjusted based on the label and your clinical response.
Can the tablets be split or crushed?
No. Swallow tablets whole with liquid. Crushing, chewing, or holding them in the mouth can cause irritation and reduce effectiveness. If swallowing is difficult, speak with your clinician about alternatives such as enteric-coated capsules. Do not mix tablets with food or hot liquids. Keep doses with meals and snacks as directed to support digestion and avoid mucosal irritation.
How are doses set for meals and snacks?
Doses are based on lipase units per kilogram and the fat content of meals and snacks. Your prescriber typically sets a starting range and adjusts to control symptoms while staying within label limits for total daily units. Keep a simple food and symptom log. Take a dose with each meal and snack as instructed. Do not change amounts without guidance from your healthcare professional and the official label.
What foods or vitamins affect pancrelipase use?
No specific foods inactivate enzymes once they reach the small intestine, but taking the medicine without food reduces benefit. Fat-soluble vitamins may be monitored in people with EPI. Alcohol can worsen pancreatitis; discuss its use with your clinician. Because the tablets need acid suppression, follow instructions for your proton pump inhibitor to support enzyme activity during meals.
Is it safe in pregnancy or while breastfeeding?
Human data are limited. Pancrelipase acts locally in the gut with minimal systemic absorption, but decisions in pregnancy and lactation should be individualized. Discuss risks, benefits, and alternatives with your prescriber. If therapy is continued, use the lowest effective units and monitor nutrition. Always follow the current prescribing information and your clinician’s advice for your specific situation.
What signs suggest my dose may be too high?
Warn your prescriber if you develop new or worsening abdominal pain, constipation, or changes suggesting bowel strictures. Excessive doses over time have been associated with fibrosing colonopathy in some patients. Also report symptoms of gout or unusual uric acid changes. Never exceed the maximum daily units on the label. Any severe or persistent symptoms should be evaluated promptly.
How does this compare with enteric-coated capsules?
Tablets require a proton pump inhibitor because they are not enteric coated, while capsules such as Creon are enteric coated to resist stomach acid. Some patients prefer capsule formats; others use tablets for flexible unit-based titration. Efficacy depends on correct units, meal timing, and adherence. Your prescriber can help choose the best formulation based on diagnosis, age, and tolerability.


