Xalatan® Ophthalmic Solution for Lowering Intraocular Pressure

What Xalatan® Is and How It Works

Xalatan Ophthalmic Solution (latanoprost 0.005%) is a prostaglandin analog used to reduce eye pressure in open-angle glaucoma and ocular hypertension. It increases the outflow of aqueous fluid through the uveoscleral pathway and is used once daily, typically in the evening. You can compare Xalatan price options, including Xalatan without insurance, when you shop at Canadian prices.

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Xalatan is supplied as a sterile eye-drop solution in a multi-dose bottle preserved with benzalkonium chloride. Most adults need one drop in the affected eye(s) once daily. Using it more than once daily may reduce the pressure-lowering effect.

Dosage and Usage

• Use one drop in the affected eye(s) once daily, preferably in the evening, as directed by your prescriber.
• Wash and dry your hands. Tilt your head back, gently pull down the lower eyelid, and instill a single drop into the pocket without touching the tip to the eye or skin.
• Close your eyes gently. Press the inner corner of the eye (near the nose) for 1 minute to reduce systemic absorption.
• If you use other eye medicines, space each product by at least 5 minutes. Use gels/ointments last.
• Remove soft contact lenses before dosing. Wait at least 15 minutes before reinserting lenses.
• If you miss a dose, skip it and use the next dose at the usual time. Do not double up.
• Do not use more than once daily. Extra doses can reduce effectiveness.
• Keep the cap tightly closed and avoid contaminating the dropper tip.

• Unopened bottles: store refrigerated at 2–8 °C (36–46 °F). Do not freeze. Protect from light.
• After first opening: you may store at room temperature up to 25 °C (77 °F) for up to 6 weeks, then discard any remaining solution.
• Travel: carry unopened bottles in an insulated pouch with cold packs. Keep opened bottles at room temperature and out of direct sun.
• Do not leave the medicine in a hot car. Avoid temperatures above 25 °C (77 °F) for opened bottles.
• When flying, keep the bottle in your carry-on. Keep the cap on to prevent leaks.

Benefits and Savings

Xalatan lowers intraocular pressure by improving fluid outflow and helps protect the optic nerve from pressure-related damage. Many people appreciate once-daily evening dosing and the steady 24‑hour pressure control. It is widely prescribed for open-angle glaucoma and ocular hypertension.

Ordering Xalatan ophthalmic solution online from YouDrugstore can offer 60–80% savings compared with typical US retail prices. These savings help if you pay the Xalatan cost without insurance or have a high deductible. Multi‑month supplies and bulk promotions may lower the per‑month cost.

See our promotions for any Xalatan coupon.

Side Effects and Safety

• Eye redness (conjunctival hyperemia)
• Transient burning, stinging, or irritation after instillation
• Itchy or dry eyes; foreign body sensation
• Eyelash growth and thickening
• Eyelid skin darkening
• Increased brown pigmentation of the iris over months (may be permanent)
• Blurred vision right after use
• Headache

Serious but less common risks include macular edema (risk is higher with aphakia or a torn posterior lens capsule), uveitis/iritis flares, herpetic keratitis reactivation, corneal edema, and bronchospasm in sensitive individuals. Seek urgent care for sudden vision changes, eye pain, or severe inflammation.

Onset Time

Pressure starts to decrease within 3–4 hours of the first dose, with peak effect around 8–12 hours. Maximum consistent pressure reduction develops over 3–5 weeks of nightly use. Your prescriber may confirm response with eye-pressure checks and adjust therapy based on your targets.

Compare With Alternatives

Generic latanoprost has the same active ingredient and once‑daily dosing. Many patients achieve comparable pressure reductions and choose it for a lower Xalatan ophthalmic solution price. See Latanoprost Ophthalmic Solution if you prefer the generic brand.

Alpha‑agonists such as Alphagan P® Ophthalmic Solution (brimonidine) are typically dosed two to three times daily and can be added when a prostaglandin alone is not enough.

Fixed combinations like latanoprost/timolol provide dual mechanisms in one bottle and simplify regimens. Your prescriber may also consider beta‑blockers, carbonic anhydrase inhibitors, or rho‑kinase inhibitors based on pressure goals and tolerability.

Combination Therapy

• Latanoprost plus timolol: often used when a single agent does not reach target IOP.
• Latanoprost plus brimonidine or a carbonic anhydrase inhibitor (dorzolamide or brinzolamide): adds further pressure reduction.
• Separate different eye drops by at least 5 minutes; use gels/ointments last.
• Use only one prostaglandin analog at a time. Do not exceed once‑daily dosing.

Patient Suitability and Cost-Saving Tips

Xalatan is used for adults with open‑angle glaucoma or ocular hypertension. It is not a treatment for acute angle‑closure. Caution is advised if you have a history of uveitis/iritis, macular edema, complicated cataract surgery, or herpetic keratitis. The preservative (benzalkonium chloride) may discolor soft lenses and can irritate dry or compromised eyes.

Discuss use during pregnancy or breastfeeding with your prescriber. Pediatric use is at a clinician’s discretion. If you notice iris color change, it may be permanent; eyelash changes are usually reversible after stopping.

Ways to save on the Xalatan cost include choosing the generic latanoprost, selecting a multi‑month supply, and watching for bulk purchase promotions. Reorder reminders can help you maintain therapy on schedule. These options can ease out‑of‑pocket costs if you need Xalatan without insurance.

Authoritative Sources

Pfizer: Xalatan (latanoprost) product information | Health Canada Drug Product Database: Xalatan/latanoprost listings and monographs

Order Xalatan® from YouDrugstore: add to cart, upload your prescription, and we ship with prompt, express, cold-chain handling.

This material is educational and does not replace professional medical advice. Always follow your prescriber’s directions and the product insert.