Xenical® (orlistat) Capsules for Weight Management

What Xenical Is and How It Works

Xenical® contains orlistat, a lipase inhibitor used for chronic weight management with a reduced-calorie diet. People often search to buy orlistat for its local action in the gut. It blocks gastrointestinal lipases, so about 25% to 30% of dietary fat is not absorbed. The unabsorbed fat exits in the stool. Xenical® is the 120 mg prescription strength taken with meals that contain fat.

YouDrugstore is a licensed Canadian pharmacy based in Manitoba, and Canadian pharmacists review each prescription before dispensing. We ship brand and generic medicines at Canadian prices, and we also carry OTC products. We work with licensed, vetted international partner pharmacies to offer authentic brands, wide selection, and affordable pricing.

Dosage and Usage

Use Xenical® as part of a reduced-calorie diet with balanced fat intake. Medical providers usually recommend diet and activity changes before and during therapy.

• Standard dose: 120 mg capsule with each main meal that contains fat, up to three times daily.
• Timing: Take during the meal or within 1 hour after finishing.
• Skip the dose if the meal is skipped or has no fat.
• Vitamin gap: Take a daily multivitamin at bedtime, or at least 2 hours after the last dose, to replace vitamins A, D, E, and K.
• No up-titration is needed. Keep fat intake moderate to reduce GI side effects.
• Missed dose: If more than 1 hour has passed since the meal, skip and resume at the next meal. Do not double up.

Storage and travel:

• Store at 15–25°C (59–77°F) in a dry place, away from moisture and heat.
• Keep capsules in the original, tightly closed container.
• For travel, keep in carry-on baggage and bring the prescription label.
• Do not freeze. Keep out of reach of children and pets.

Benefits and Savings

Xenical® supports gradual weight loss when used with diet and physical activity. Many patients see greater loss than with lifestyle changes alone. Clinical studies show more people achieve 5% to 10% weight reduction at one year versus diet alone. Weight maintenance and lower rates of regain are also observed with continued use.

Orlistat acts locally with minimal systemic absorption. It is an oral capsule, which some prefer over injections. It may improve cardiometabolic markers such as LDL cholesterol and blood pressure. For those comparing orlistat 120 mg price in USA markets, Canadian pharmacy pricing can be lower.

Ordering from YouDrugstore can mean 60% to 80% savings compared to typical US prices. We also offer friendly customer-service chat during posted hours for ordering support. Reorder reminders are available, and multi-month supplies can reduce your per-month cost.

Side Effects and Safety

Gastrointestinal effects are the most common and tend to occur early. They are usually mild to moderate and improve with a lower-fat diet.

• Common: oily or fatty stools, gas with discharge, fecal urgency, increased bowel movements, abdominal pain, nausea.
• Vitamin effects: reduced absorption of vitamins A, D, E, and K; take a daily multivitamin at a separate time.
• Less common but serious: severe liver injury (rare), oxalate nephropathy or kidney stones, cholelithiasis, pancreatitis, rectal bleeding, allergic reactions.
• Drug interactions: cyclosporine (separate and monitor levels), warfarin (monitor INR due to vitamin K changes), levothyroxine (separate by at least 4 hours and monitor TSH), anticonvulsants (watch for seizure control changes), amiodarone (reduced levels reported).
• Do not use: pregnancy, chronic malabsorption syndrome, cholestasis. Not recommended during breastfeeding.

Limit dietary fat to reduce GI effects. Seek medical care if severe abdominal pain, signs of liver problems, or persistent bleeding occur.

Onset Time

Changes in bowel habits can begin after the first dose with a fatty meal. Weight changes often start within the first 2 to 4 weeks when combined with calorie restriction. Most loss occurs over 3 to 6 months, and continued use helps maintain results when paired with ongoing diet and activity.

Compare With Alternatives

GLP-1 therapies offer greater average weight loss but differ in route, cost, and side effects. Wegovy® (semaglutide 2.4 mg) is a weekly injection approved for obesity with strong efficacy but requires injections and can cause nausea. Ozempic® (semaglutide) is indicated for type 2 diabetes, with notable weight loss; some providers use it off-label for weight control. Oral semaglutide, Rybelsus®, treats type 2 diabetes and also reduces weight, but it is not specifically approved for obesity.

Compared with Xenical®, GLP-1 agents often lead to more weight loss, but they have systemic effects and can be costly. Orlistat is oral, non-systemic, and may suit those avoiding needles or with specific tolerability needs.

Another option is over-the-counter Alli® (orlistat 60 mg) in some markets. It delivers half the prescription strength and has similar GI effects. Prescription Xenical® may provide greater efficacy at 120 mg when clinically appropriate.

Combination Therapy

Orlistat is intended to complement a reduced-calorie diet and increased physical activity. Behavioral support, nutrition counseling, and regular follow-up help maintain results. Vitamin supplementation is standard to replace fat-soluble vitamins. Combining with other weight-loss drugs is not routine and should be supervised by a healthcare provider due to interaction and safety considerations.

Patient Suitability and Cost-Saving Tips

Orlistat may be considered for adults with obesity, or for those overweight with weight-related risk factors, when diet and activity alone have not achieved sufficient results. It is not suitable in pregnancy, with cholestasis, or with chronic malabsorption syndromes. Review current medicines and supplements to assess interaction risks.

To lower costs, consider multi-month supplies when appropriate, which can reduce per-month pricing. Set reorder reminders so therapy is not interrupted. For current offers and bulk options, see our orlistat coupon page.

Explore condition guides like Obesity and Weight Loss to learn more about long-term management. If you are comparing treatment classes, our articles Mounjaro Vs Zepbound Which One Works Best For You and Best Weight Loss Injections Top Options To Consider offer practical insights on GLP-1 and other injection options.

Authoritative Sources

Review the FDA Medication Guide for orlistat on the FDA Orlistat Label (Medication Guide), and confirm Canadian approval details through the Health Canada Drug Product Database (Xenical).

YouDrugstore makes ordering simple and discreet. Our team supports you from checkout to delivery, and pharmacists can address medication questions. We offer prompt, express, cold-chain shipping to the US where required.

This material is general information. It does not replace medical advice, diagnosis, or treatment. Always speak with a qualified healthcare professional about your health, medicines, and dosing. Prescription products ship only after the pharmacy reviews and verifies a valid prescription.